Evaluation of Acute Lung Injury
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 1)
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In order to fulfill its primary function as a gas exchanger the lung has a very large contact surface between air and blood. While this is an advantage for gas exchange it also provides a very large target for numerous mediators of lung injury. The barrier set up between air and blood is made up of alveolar epithelium and capillary endothelium which enclose the connective tissue fibres of the interstitial space. Although this barrier is freely permeable to water there is an important mechanism which prevents exudation of liquid into the alveolar space. This is based on two factors
a low permeability of the barrier to hydrophilic solutes and
active transport of solute, including albumin, across the barrier into the blood.
KeywordsLung Injury Acute Lung Injury Adult Respiratory Distress Syndrome Alveolar Oedema Connective Tissue Fibre
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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