Abstract
The initial impetus for the establishment of the first Coronary Care Units in 1962 in Kansas City, Toronto and Philadelphia came about from the recognition that many patients with acute myocardial infarction died suddenly. It was therefore hoped that resuscitative efforts could reverse this remarkable mortality trend. The complementary goal was to provide immediate therapy for cardiac arrhythmias assumed to be the cause of sudden death in these patients [8]. Later the concept of treating the so-called “warning arrhythmias” — which means ventricular dysrhythmias leading to ventricular fibrillation — received considerable support, although the significance and treatment of these ectopic beats remain an important and controversial issue [10]. However as long as we believe in the significance of the so-called warning arrhythmias (e.g. ventricular premature beats ≥ Lown III) [11] during the first phase of acute myocardial infarction we should recognize them properly and treat them by the correct antiarrhythmic drug in the correct dosage.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Chernow B (ed) (1983) The Pharmacologic Approach to the Critically Ill Patient. Williams and Wilkins, Baltimore
Dalen JE, Goldberg RJ et al (1984) Therapeutic Interventions in Acute Myocardial Infarction. Chest 8ó: 257–262
De Silva RA, Lown B et al (1981) Lignocaine Prophylaxis in Acute Myocardial Infarction: An Evaluation of Randomised Trials. Lancet 2: 855–858
Follath F, Ritz R et al (1981) Verbesserte Lidocaindosierung durch Serumkonzentrationsbestimmungen bei Patienten mit Myokardinfarkt. Verh Dtsch Ges Inn Med 87: 427–429
Follath F, Ritz R et al (1982) Verlangsamte Lidocain-Elimination and Dosisanpassung bei Patienten mit Herzinsuffizienz. Schweiz Med Wschr 112: 789–791
Gianelly R, Groeben JO et al (1967) Effect of lignocaine on ventricular arrhythmias in patients with coronary heart disease. N Engl J Med 277: 1215–1219
Harrison DC (1978) Should Lidocaine be Administered Routinely to Patients after Acute Myocardial Infarction? Circulation 58: 581–584
Karliner JS, Gregoratos G (1981) Coronary Care. Churchill Livingstone New York
Lie KI, Wellens HJ et al (1974) Lidocaine in the prevention of Primary Ventricular Fibrillation. N Engl J Med 291: 1324–1326
Lie KI, Wellens HJ et al (1975) Observations on Patients with Primary Ventricular Fibrillation Complicating Acute Myocardial Infarction. Circulation 52: 755–759
Lown B, Klein MD et al (1969) Coronary and Precoronary Care. Am J Med 46: 705–708
Noneman JW, Rogers JF (1978) Lidocaine Prophylaxis in Acute Myocardial Infarction. Medicine 57: 501–515
Ritz R (1981) Qualitätskontrolle einer rechnergestützten Arrhythmie-Ueberwachung. Schweiz Med Wschr 111: 997–1000
Ritz R, Bernet F et al (1982) Wirksamkeit der antiarrhytmischen Therapie mit Lidocain beim akuten Myokardinfarkt. Schweiz Med Wschr 112: 1638 (abstract)
Ritz R (19847 Clinical Experience with Computerized ICU-monitoring. Resuscitation 11:249–253
Romhildt D W, Bloomfield S S, Chou T, Fowler N O (1973) Unreability of Conventional Electrocardiographic Monitoring for Arrhythmia Detection in Coronary Care Units. Amer J Cardiol 31: 457–461
Shah P M, Arnold J M et al (1977) Automatic Real Time Arrhythmia Monitoring in the Intensive Coronary Care Unit. Amer J Cardiol 39: 701–708
Sheiner L B, Rosenberg B et al (1972) Modelling of individual pharmacokinetics for computer aided drug dosage. Computer Biomedical Research 5: 441–459
Sheiner L B, Rosenberg B et al (1977) Estimation of population characteristics of pharmacokinetics parameters from routine clinical data. J Pharmacokin Biopharm 5: 445–479
Vaughan-Williams E M (1975) Classification of antidysrhytmic drugs. J Pharmacol Ther 1: 115–138
Vetter N J, Julian D G (1975) Comparison of Arrhythmia Computer and Conventional Monitoring in Coronary Care Unit. Lancet 1: 1151–1154
Vozeh S, Muir K T et al (1981) Predicting individual phenytoin dosage. J Pharmacokinetics and Biopharmaceutics 9: 131
Vozeh S, Berger M, Wenk M, Ritz R, Follath F (1984) Rapid Prediction of Individual Dosage Requirements for Lignocaine. Clin Pharmacokinetics 9: 354–363
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Ritz, R., Follath, F. (1986). Antiarrhythmic Therapy in Acute Myocardial Infarction: Individualised Treatment with Lidocaine. In: Vincent, J.L. (eds) 6th International Symposium on Intensive Care and Emergency Medicine. Update in Intensive Care and Emergency Medicine, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82801-0_28
Download citation
DOI: https://doi.org/10.1007/978-3-642-82801-0_28
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16508-8
Online ISBN: 978-3-642-82801-0
eBook Packages: Springer Book Archive