Advertisement

The Role of the Pathologist in the Clinical Management of Malignant Liver Tumors

  • P. P. Anthony
Conference paper
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 100)

Abstract

A multiplicity of different tumours can arise in the liver, each with its own distinctive pathology but many of these are rarities and useful information about them is scant. In tropical Africa and Southeast Asia, liver cell (hepatocellular) carcinoma is one of the commonest of all malignancies but this tumour is rare in Western countries and is seldom amenable to surgery. Bile duct carcinoma (cholangiocarcinoma) is next in importance. It occurs more or less equally throughout the world except in Southeast Asia, where a high incidence is seen in those infested with liver flukes. All other primary tumours are rare though some, like liver cell adenoma, hemangiosarcoma and tumours occurring in children, are of considerable interest. In Western countries, secondary tumours, particularly those from primary carcinomas of the gastrointestinal tract, breast and lung, are by far the commonest and their presence is no longer regarded as hopeless for the patient.

Keywords

Bile Duct Primary Biliary Cirrhosis Granular Cell Tumour Bile Duct Carcinoma Malignant Liver Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Aisner SC, Khaneja S, Ramirez 0 (1982) Multiple granular cell tumours of the gallbladder and biliary tree. Arch Pathol Lab Med 106: 470–471Google Scholar
  2. 2.
    Anthony PP (1981) The pathology of primary cancer of the liver. In: Friedman M, Ogawa M, Kisner D (eds) Diagnosis and treatment of upper gastrointestinal tumours. Excerpta Medica, Amsterdam, p 79Google Scholar
  3. 3.
    Anthony PP (1985) Tumours and tumour-like lesions of the liver and biliary tract. In: MacSween RNM, Anthony PP, Scheuer PJ (eds) Pathology of the liver, 2nd edn. Churchill Livingstone, Edinburgh (in press)Google Scholar
  4. 4.
    Berman MM, Libbey NP, Foster JH (1980) Hepatocellular carcinoma polygonal cell type with fibrous stroma–an atypical variant with a favourable prognosis. Cancer 46: 1448–1455PubMedCrossRefGoogle Scholar
  5. 5.
    Cameron HM, Linsell DA, Warwick GP (eds) (1976) Liver cell cancer. Elsevier, AmsterdamGoogle Scholar
  6. 6.
    Collier NA, Weinbren K, Bloom SR, Lee YC, Hodgson HJF, Blumgart LH (1984) Neurotensin secretion by fibrolamellar carcinoma of the liver. Lancet 1: 538–540PubMedCrossRefGoogle Scholar
  7. 7.
    Craig JR, Peters RL, Edmondson HA, Omata M (1980) Fibrolamellar carcinoma of the liver: a tumour of adolescents and young adults with distinctive clinico-pathologic features. Cancer 46: 372–379PubMedCrossRefGoogle Scholar
  8. 8.
    Gibson JB, Sobin LH (1978) Histological typing of tumours of the liver, biliary tract and pancreas. International histological classification of tumours No. 20. World Health Organisation, GenevaGoogle Scholar
  9. 9.
    Horie Y, Katoh S, Yoshida H, Imaska T, Suou T, Hirayama C (1983) Pedunculated hepatocellular carcinoma. A report of three cases and review of literature. Cancer 51: 746–751Google Scholar
  10. 10.
    Ishak KG (1976) Mesenchymal tumours of the liver. In: Okuda K, Peters RL (eds) Hepatocellular carcinoma. Wiley, New York, p 247Google Scholar
  11. 11.
    Ishak KG, Glunz PR (1967) Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases. Cancer 20: 396–422PubMedCrossRefGoogle Scholar
  12. 12.
    Ishak KG, Rabin L (1975) Benign tumours of the liver. Med Clin North Am 59: 995–1013PubMedGoogle Scholar
  13. 13.
    Ishak KG, Willis GW, Cummins SD, Bullock AA (1977) Biliary cystadenoma and cystadenocarcinoma. Report of 14 cases and review of the literature. Cancer 38: 322–338CrossRefGoogle Scholar
  14. 14.
    Lai CL, Wu PC, Lam KC, Todd D (1979) Histologic prognostic indicators in hepatocellular carcinoma. Cancer 44: 1677–1683PubMedCrossRefGoogle Scholar
  15. 15.
    Mercadier M, Bodard M, Fingerhut A, Chigot JP (1984) Papillomatosis of the intrahepatic bile ducts. World J Surg 8: 30–35PubMedCrossRefGoogle Scholar
  16. 16.
    Munoz N, Linsell A (1982) Epidemiology of primary liver cancer. In: Correa P, Haenszel W (eds) Epidemiology of cancer of the digestive tract. Nijhoff, The Hague, p 161CrossRefGoogle Scholar
  17. 17.
    Nakashima T, Okuda K, Kojiro M, Jimi A, Yamaguchi R, Sakamoto K, Ikavi T (1983) Pathology of hepatocellular carcinoma in Japan; 232 consecutive cases autopsied in ten years. Cancer 51: 863–877PubMedCrossRefGoogle Scholar
  18. 18.
    Nime F, Pickren JW, Vana J, Aronoff BL, Baker HW, Murphy GP (1979) The histology of liver tumours in oral contraceptive users observed during a national survey by the American College of Surgeons Commission on Cancer. Cancer 44: 1481–1489PubMedCrossRefGoogle Scholar
  19. 19.
    Okuda K, Peters RL (eds) (1976) Hepatocellular carcinoma. Wiley, New YorkGoogle Scholar
  20. 20.
    Remmer H, Bolt HM, Bannasch P, Popper H (eds) (1978) Primary liver tumours. Falk Symposium 25. MTP Press, LancasterGoogle Scholar
  21. 21.
    Tao LC, Ho CS, McLoughlin MJ, Evans WK, Donat EE (1984) Cytologic diagnosis of hepatocellular carcinoma by fine needle aspiration biopsy. Cancer 53: 547–552PubMedCrossRefGoogle Scholar
  22. 22.
    Weiss SW, Enzinger FM (1982) Epithelioid haemangioendothelioma. A vascular tumour often mistaken for a carcinoma. Cancer 50: 970–981Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1986

Authors and Affiliations

  • P. P. Anthony
    • 1
  1. 1.Postgraduate Medical SchoolUniversity of ExeterDevonGreat Britain

Personalised recommendations