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Preliminary Results of a Randomized Study of Intrahepatic Infusion Versus Systemic Infusion of 5-Fluoro-2′ -deoxyuridine for Metastatic Colorectal Carcinoma

  • N. Kemeny
  • J. Daly
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 100)

Abstract

Development of a totally implantable infusion pump produced a renewed interest in hepatic infusional therapy. An initial study employing this pump by Ensminger and associates and the continuous hepatic infusion of 5-fluoro-2′-deoxyuridine (FUdR) observed an 83% response rate [1]. However, further work with this method brought the mean response rate down to 59% (Table 1) [2], which, however, is still higher than the mean response rate obtained with systemic chemotherapy.

Keywords

Hepatic Artery Systemic Group Extrahepatic Disease Liver Involvement Metastatic Colorectal Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1986

Authors and Affiliations

  • N. Kemeny
    • 1
  • J. Daly
    • 1
  1. 1.Solid Tumor Service, Department of MedicineMemorial Sloan-Kettering Cancer CenterUSA

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