Preliminary Results of a Randomized Study of Intrahepatic Infusion Versus Systemic Infusion of 5-Fluoro-2′ -deoxyuridine for Metastatic Colorectal Carcinoma
Development of a totally implantable infusion pump produced a renewed interest in hepatic infusional therapy. An initial study employing this pump by Ensminger and associates and the continuous hepatic infusion of 5-fluoro-2′-deoxyuridine (FUdR) observed an 83% response rate . However, further work with this method brought the mean response rate down to 59% (Table 1) , which, however, is still higher than the mean response rate obtained with systemic chemotherapy.
KeywordsToxicity Catheter Hydration Albumin Oncol
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