Skip to main content
SpringerLink
Log in

Neurotensin in Human Small Cell Lung Carcinoma

  • Conference paper
Book cover Peptide Hormones in Lung Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 99))

Abstract

A question of fundamental importance in the biology of human lung cancer is whether the hormones produced by lung tumours exert a positive influence on the growth of the tumour through an autocrine function or whether hormone production simply reflects a derepression of genetic material consequent to dedifferentiation. The former possibility would require the presence of hormone receptors on tumour cell membranes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Emson PC, Goedert M, Horsfield P, Rioux F, St Pierre S (1982) The regional distribution and Chromatographic characterization of neurotensin-like immunoreactivity in the rat central nervous system. J Neurochem 38: 992–999.

    Article  PubMed  CAS  Google Scholar 

  • Goedert M, Sturmey N, Williams BJ, Emson PC (1984) The comparative distribution of xenopsin-and neurotensin-like immunoreactivity in Xenopus laevis and rat tissues. Brain Res 308: 273–280.

    Article  PubMed  CAS  Google Scholar 

  • Greco FA, Oldham RK (1979) Small cell lung cancer. N Engl J Med 301: 355–358.

    Article  PubMed  CAS  Google Scholar 

  • Moody TW, Pert CB, Gazdar RF, Carney DN, Minna JD (1981) High levels of intracellular bombesin characterize human small cell lung carcinoma. Science 214: 1246–1248.

    Article  PubMed  CAS  Google Scholar 

  • Sorenson GD, Bloom SR, Ghatei MA, Del Prete SA, Cate CC, Pettingill OS (1982) Bombesin production by human small cell carcinoma of the lung. Regul Pept 4: 59–66.

    Article  PubMed  CAS  Google Scholar 

  • Yamaguchi K, Abe K, Kameya T, Adachi I, Taguchi S, Otsubo K, Yanaihara N (1983) Production and molecular size heterogeneity of immunoreactive gastrin releasing peptide in fetal and adult lungs and primary lung tumours. Cancer Res 43: 3932–3939.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinical Oncology and Radiotherapeutics Unit and Neurochemical Pharmacology Unit, MRC Centre, Hills Road, Cambridge, CB2 2QH, Great Britain

    J. G. Reeve, M. Goedert, P. C. Emson & N. M. Bleehen

Authors
  1. J. G. Reeve
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Goedert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. C. Emson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. M. Bleehen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Zentrum für Innere Medizin Medizinische Klinik und Poliklinik Schwerpunkt Hämatologie, Onkologie, Immunologie, Klinikum der Philipps-Universität Marburg, Baldingerstrasse, 3550, Marburg, Deutschland

    Klaus Havemann

  2. Department of Pathology, Dartmouth Medical School, Hanover, NH, 03756, USA

    George Sorenson MD

  3. Klinik Bergisch-Land, Im Saalscheid 5, 5600, Wuppertal-Ronsdorf 21, Deutschland

    Claus Gropp

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Reeve, J.G., Goedert, M., Emson, P.C., Bleehen, N.M. (1985). Neurotensin in Human Small Cell Lung Carcinoma. In: Havemann, K., Sorenson, G., Gropp, C. (eds) Peptide Hormones in Lung Cancer. Recent Results in Cancer Research, vol 99. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82533-0_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-82533-0_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15504-1

  • Online ISBN: 978-3-642-82533-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation