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Regulation of Hormone Production in Small Cell Carcinoma of the Lung

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Book cover Peptide Hormones in Lung Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 99))

Abstract

Patients with pulmonary carcinoma frequently have elevated levels of one or more circulating tumor-produced hormones. This is particularly characteristic of small cell carcinoma of the lung (SCCL), where an increased frequency of hormone production is seen more commonly than in other types of lung cancer. The most frequently elevated hormones in such patients are calcitonin (CT), ACTH and neurophysins (Sorenson et al. 1984a). In addition to the noteworthy frequency of hormone production by tumors in these patients, there is also a wide variety of hormones produced by individual SCCL tumors. The reasons for the common occurrence and the great variety of hormones produced by SCCL are unknown, as are the molecular mechanisms involved.

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Authors and Affiliations

  1. Department of Pathology, Dartmouth Medical School, Hanover, NH, 03756, USA

    G. D. Sorenson, C. C. Cate & O. S. Pettengill

Authors
  1. G. D. Sorenson
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  2. C. C. Cate
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  3. O. S. Pettengill
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Editors and Affiliations

  1. Zentrum für Innere Medizin Medizinische Klinik und Poliklinik Schwerpunkt Hämatologie, Onkologie, Immunologie, Klinikum der Philipps-Universität Marburg, Baldingerstrasse, 3550, Marburg, Deutschland

    Klaus Havemann

  2. Department of Pathology, Dartmouth Medical School, Hanover, NH, 03756, USA

    George Sorenson MD

  3. Klinik Bergisch-Land, Im Saalscheid 5, 5600, Wuppertal-Ronsdorf 21, Deutschland

    Claus Gropp

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© 1985 Springer-Verlag Berlin Heidelberg

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Sorenson, G.D., Cate, C.C., Pettengill, O.S. (1985). Regulation of Hormone Production in Small Cell Carcinoma of the Lung. In: Havemann, K., Sorenson, G., Gropp, C. (eds) Peptide Hormones in Lung Cancer. Recent Results in Cancer Research, vol 99. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82533-0_15

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  • DOI: https://doi.org/10.1007/978-3-642-82533-0_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15504-1

  • Online ISBN: 978-3-642-82533-0

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