Abstract
It is well established that the most common nonendocrine tumor associated with peptide hormone production is lung carcinoma. Many peptide hormones have been reported to be produced by lung tumors, and their biochemical and immunological characteristics have been described (Odell 1981; Orth 1981; Abe et al. 1984a). Recent progress in peptide hormone research has revealed that many previously unknown peptides are present in vivo, and one of these newly discovered peptides, GRP, has been shown to be an important product of primary lung tumors (Moody et al. 1981; Wood et al. 1981; Erisman et al. 1982; Sorenson et al. 1983; Yamaguchi et al. 1983a). We also found that small cell lung carcinoma can produce GRF (Yamaguchi et al. 1983b). In the present study, a large number of primary lung tumors were examined for production of 18 peptides, including classic and new peptides.
This investigation was supported in part by a Grant-in-Aid from the Ministry of Health and Welfare for Comprehensive 10-year strategy for Cancer Control, by Grants-in-Aid for Cancer Research (57–8, 57 S, 58–12, 59–1, 59 S-1, 60 S) and a Research Grant for Intractable Diseases from the Ministry of Health and Welfare, by Grants-in-Aid for Cancer Research from the Ministry of Education, Science and Culture, and by the Special Coordination Fund from the Science and Technology Agency, Japan
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© 1985 Springer-Verlag Berlin Heidelberg
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Yamaguchi, K. et al. (1985). Peptide Hormone Production in Primary Lung Tumors. In: Havemann, K., Sorenson, G., Gropp, C. (eds) Peptide Hormones in Lung Cancer. Recent Results in Cancer Research, vol 99. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82533-0_12
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DOI: https://doi.org/10.1007/978-3-642-82533-0_12
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