Antenatal Glucocorticoid Therapy: Hormone Concentrations

  • Philip L. Ballard
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 28)


The use of prenatal glucocorticoid therapy for prevention of RDS has provided opportunities to study serum concentrations of administered hormones in both mother and fetus. Data are available from women treated in the third trimester with betamethasone, dexamethasone, and hydrocortisone. The amount of transplacental passage of these corticosteroids and the kinetics of their appearance and disappearance in the fetal circulation are discussed. In addition, I review the effect of glucocorticoid treatment on various endogenous hormones in both mother and fetus.


Premature Infant Obstet Gynecol Cortisol Concentration Fetal Circulation Maternal Circulation 
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Copyright information

© Springer-Verlag Berlin, Heidelberg 1986

Authors and Affiliations

  • Philip L. Ballard
    • 1
  1. 1.Department of Pediatrics and Cardiovascular Research InstituteUniversity of California Medical CenterSan FranciscoUSA

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