Surgical Intervention and Metastasis

  • R. Keller
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 98)


It is now appreciated that the tumor-host relationship is intimate and complex, and that the outcome of tumor disease depends on many variables pertaining to both host and tumor. This implies that each tumor-host relationship has individual features; accordingly, there are few valid general conclusions to be drawn from the immense effort focused on this problem. Despite these reservations it is possible to identify certain major issues that are applicable in a variety of clinical and experimental situations. As some of these issues may well be relevant to the establishment of more appropriate therapeutic regimens they are briefly outlined here. The experimental examples were derived from the D-12 rat fibrosarcoma, a model studied extensively in this laboratory (Keller 1980, 1981, to be published).


Primary Tumor Disseminate Tumor Cell Viable Tumor Cell Spontaneous Metastasis Metastatic Tumor Growth 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • R. Keller
    • 1
  1. 1.Institut für Immunologie und VirologieUniversität Zürich, Arbeitsgruppe für ImmunbiologieZürichSwitzerland

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