Perioperative and Conventionally Timed Chemotherapy in Operable Breast Cancer

  • A. Goldhirsch
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 98)

Abstract

Adjuvant chemotherapy with CMF in pathological stage II breast cancer has been shown by the Milan Group to produce a disease-free survival and overall survival advantage at 6 years in premenopausal patients (Bonadonna et al. 1978). The value of adjuvant chemotherapy in postmenopausal patients is less well established, although it seems likely to be real. It has been suggested that treatment success may well be dose related in all patients (Bonadonna and Valagussa 1981) and toxicity related (Carpenter et al. 1982). The role of adjuvant chemotherapy in node-negative patients has still to be confirmed (Senn et al. 1981).

Keywords

Toxicity Oncol Bacillus Methotrexate Folate 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • A. Goldhirsch
    • 1
  1. 1.Ludwig Institut für Krebsforschung, InselspitalBernSwitzerland

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