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Chemotherapeutic Results in Small Cell Lung Cancer

  • Chapter
Book cover Small Cell Lung Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 97))

Abstract

Small cell lung cancer (SCLC) is a distinct and well-reproducible histopathological entity (Hirsch et al. 1982). Besides morphological criteria, SCLC is distinguished from other cell types by ultrastructural, endocrine, cytogenetic, cell-kinetic, and clinical findings (Gropp et al. 1980; Hattori et al. 1972; Whang-Peng et al. 1982). The high labeling index (Muggia et al. 1974; Pettengill et al. 1980) and short doubling time (Straus 1974; Weiss et al. 1970) are manifested clinically by fast growth, rapid onset of signs and symptoms, and a tendency toward early and widespread dissemination (Hansen et al. 1978; Muggia and Chevru 1974). Accordingly, the median survival time from diagnosis without treatment is 2.8 months, with only 4.2% of patients still alive at 1 year (Hyde et al. 1965; Zelen 1973).

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  1. Innere Universitätsklinik und Poliklinik (Tumorforschung), Westdeutsches Tumorzentrum, Hufelandstrasse 55, 4300, Essen, Federal Republic of Germany

    N. Niederle & J. Schütte

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  1. Innere Klinik und Poliklinik (Tumorforschung) Westdeutsches Tumorzentrum, Universitätsklinikum Essen, Hufelandstrasse 55, 4300, Essen, Federal Republic of Germany

    Siegfried Seeber

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Niederle, N., Schütte, J. (1985). Chemotherapeutic Results in Small Cell Lung Cancer. In: Seeber, S. (eds) Small Cell Lung Cancer. Recent Results in Cancer Research, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82372-5_12

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  • DOI: https://doi.org/10.1007/978-3-642-82372-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82374-9

  • Online ISBN: 978-3-642-82372-5

  • eBook Packages: Springer Book Archive

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