Abstract
In January 1974, the Medical Breast Service at M.D. Anderson Hospital began investigation of a combination of fluorouracil, doxorubicin (adriamycin), and cyclophosphamide (FAC) as adjuvant therapy for stage II and III breast cancer. Earlier results of these studies have been published [1–3]. Here the results of the initial study are presented, with the median follow-up of FAC-treated patients being 85 months. As this is the first adjuvant program utilizing FAC with such long-term follow-up, it seemed important to review the results of stage II and III patients so treated.
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References
Buzdar AU, Gutterman JU, Blumenschein GR et al. (1978) Intensive postoperative chemoimmunotherapy for patients with stage II and stage III breast cancer. Cancer 41: 1064–1075
Buzdar AU, Blumenschein GR, Gutterman JU et al. (1979) Postoperative adjuvant chemotherapy with fluorouracil, doxorubicin, cyclophosphamide, and BCG vaccine: A follow-up report. JAMA 242: 1509–1513
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Buzdar AU, Blumenschein GR, Smith T et al. (1984) Adjuvant chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide, with or without Bacillus Calmette-Guerin and with or without irradiation in operable breast cancer. Cancer 53: 384–389
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© 1984 Springer-Verlag Berlin · Heidelberg
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Blumenschein, G.R., Buzdar, A.U., Hortobagyi, G.N. (1984). FAC + BCG as Adjuvant Therapy in Breast Cancer: An 8-Year Update. In: Senn, HJ. (eds) Adjuvant Chemotherapy of Breast Cancer. Recent Results in Cancer Research, vol 96. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82357-2_15
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DOI: https://doi.org/10.1007/978-3-642-82357-2_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-82359-6
Online ISBN: 978-3-642-82357-2
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