Evaluation of Schedule Dependency of Anticancer Drugs in the Human Tumor Clonogenic Assay
The cytotoxicity of anticancer drugs may depend on the schedule of administration as well as on the dose used. There are limited data concerning the evaluation of drug schedules using human tumor models. The purpose of our study was to evaluate schedule dependency of anticancer drugs by comparing 1-h to continuous drug exposures in the human tumor clonogenic assay (HTCA) (Salmon et al. 1978).
KeywordsDoxorubicin Myeloma Etoposide Bleomycin Vinblastine
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