Zusammenfassung
In dieser Arbeit wird der Versuch unternommen, das räumliche Wachstum und die Behandlung von Tumoren zu modellieren und im Computerexperiment zu simulieren. Als ausgewähltes Beispiel wird der Tumorangiogenesis-Effekt behandelt. Durch den vorgestellten Ansatz zeichnet sich die Möglichkeit ab, künftig vor einer klinischen Behandlung die optimale Methode und den günstigsten Behandlungszeitaugenblick im Simulationsexperiment zu ermitteln.
Summary
In this paper the attempt is made to simulate spatial tumor growth and treatment. Special interest is given to the modelling of the tumor-angiogenesis effect. In the future it seems possible to predict the optimal method and time of cancer treatment by simulation prior to clinical therapy.
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Schrifttum
Rittgen, W.: Controlled branching processes and their application to normal and malignant haematopoiesis. Bulletin of Mathematical Biology, Vol. 45, No. 4, 617–626 (1983).
Piantadosi, St., Hazelrig, J.B., Turner, M.E.: A model of tumor growth based on cell cycle kinetics. Mathematical Bioscience, 66, 283–306 (1983).
Düchting, W.: Krebs, ein instabiler Regelkreis–Versuch einer Systemanalyse. Kybernetik, Band 5, Heft 2, 70–77 (1968).
Düchting, W.: Computer simulation of abnormal erythropoiesis–an example of cell renewal regulating systems. Biomedizinische Technik, Bd. 21, Heft 2, 34–43 (1976).
Düchting, W., Dehl, G.: Spatial structure of tumor growth: A simulation study. IEEE Transactions on Systems, Man and Cybernetics, SMC-10, No. 6, 292–296 (1980).
Düchting, W., Vogelsaenger, Th.: Three-dimensional pattern generation applied to spheroidal tumor growth in a nutrient medium, Int. J. Bio-Medical Computing, 12, 377–392 (1981).
Lloyd, D., Poole, R.K., Edwards, St. W.: The cell division cycle. Academic Press, London 1982.
Düchting, W., Vogelsaenger, Th.: Aspects of modelling and simulating tumor growth and treatment, Journal of Cancer Research and Clinical Oncology, No. 105, 1–12 (1983).
Folkman, J., Haudenschild, Ch.: Angiogenesis in vitro. nature, Vol. 288, 551–556 (1980).
Folkman, J., Langer, R., Linhardt, R.J., Haudenschild, Ch., Taylor., St.: Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone. Science, Vol. 221, No. 4612, 719–725 (1983).
Düchting, W., Vogelsaenger, Th.: Three-dimensional simulation of tumor growth. Simulation, Vol. 40, No. 5, 163–169 (1983).
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© 1984 Springer-Verlag Berlin Heidelberg
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Düchting, W., Vogelsaenger, T. (1984). Systemanalyse des Dreidimensionalen Tumorwachstums Sowie Verschiedener Behandlungsstrategien. In: Möller, D.P.F. (eds) Erwin-Riesch Arbeitstagung Systemanalyse biologischer Prozesse. Medizinische Informatik und Statistik, vol 52. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82266-7_12
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DOI: https://doi.org/10.1007/978-3-642-82266-7_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-13371-1
Online ISBN: 978-3-642-82266-7
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