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Leukemia pp 269-289 | Cite as

Allogeneic Bone Marrow Transplantation in Leukemia

  • H.-J. Kolb
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 93)

Abstract

Over the past 20–30 years there has been considerable progress in the treatment of acute leukemia. In the majority of children with acute lymphoblastic leukemia (ALL) a cure is a possibility with intensive combination chemotherapy and prophylactic treatment of sanctuary sites [64, 90, 103] such as the central nervous system. The prognosis for patients with acute nonlymphocytic leukemia (ANL) is less favorable. However, complete remissions can be achieved in a majority and long-term survival in a minority of patients with severely myelotoxic treatment regimens [45, 138, 143]. In contrast to acute leukemia, the prognosis of chronic myeloid leukemia [CML] has changed little with modern chemotherapy [105].

Keywords

Bone Marrow Transplantation Marrow Transplantation Chronic GVHD Allogeneic Bone Marrow Transplantation Interstitial Pneumonitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1984

Authors and Affiliations

  • H.-J. Kolb
    • 1
  1. 1.Institut für Hämatologie, Abteilung ImmunologieGesellschaft für Strahlen- und Umweltforschung mbHNeuherberg/OberschleissheimGermany

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