Skip to main content

Part of the book series: Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology ((HDBRADIOL,volume 20))

  • 49 Accesses

Zusammenfassung

Die Haut ist das bei der Strahlentherapie bösartiger Tumoren am häufigsten mitbestrahlte normale Gewebe. Zudem sind seine Reaktionen offenkundig. In früheren Zeiten haben diese häufig die an tiefgelegenen Tumoren erreichbaren Strahlendosen und damit die Therapieergebnisse begrenzt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Arcangeli G, Friedman M, Paoluzi R (1974) A quantitative study of late radiation effect on normal skin and subcutaneous tissue in human beings. Br J Radiol 47: 44–50

    PubMed  CAS  Google Scholar 

  • Aristizabal SA, Miller RC, Schlichtemeier AL, Jones SE, Boone ML (1977) Adriamycin-irradiation cutaneous complications. Int J Radiat Oncol Biol Phys 2: 325–31

    PubMed  CAS  Google Scholar 

  • Bates TD, Peters LJ (1975) Dangers of the clinical use of the NSD formula for small fraction numbers. Br J Radiol 48: 773

    PubMed  CAS  Google Scholar 

  • Berry RJ, Wiernik G, Patterson TJS (1974) Skin tolerance to fractionated x-irradiation in the pig — how good a predictor is the NSD formula? Br J Radio! 47: 185–190

    CAS  Google Scholar 

  • Bewley DK, Fowler J, Morgan RL, Silvester JL, Turner BA (1963) Experiments on the skin of pigs with fast neutrons and 8 MeV x-rays, including some effects of dose fractionation. Br J Radiol 36: 107–115

    Google Scholar 

  • Bewley DK, Field SB, Morgan RL, Page BC, Parnell CJ (1967) The response of pig skin to fractionated treatments with fast neutrons and x-rays. Br J Radiol 40: 745–770

    Google Scholar 

  • Birkner R, Hoffmann B (1961) Unterhautindurationen nach Telekobalttherapie. Strahlentherapie 116: 463–477

    PubMed  CAS  Google Scholar 

  • Borak J (1936) The radiation biology of the cutaneous glands. Radiology 27: 651–655

    CAS  Google Scholar 

  • Brenk HAS van den (972) Macro-colony assay for measurements of reparative angiogenesis after x-irradiation. Int J Radiat Biol 21:607–611

    Google Scholar 

  • Brennan D, Young CMA, Hopewell JW, Wiernik G (1976) The effects of varied numbers of dose fractions on the tolerance of normal human skin. Clin Radio! 27: 27–32

    CAS  Google Scholar 

  • Brown JM, Probert JC (1973) Long-term recovery of connective tissue after irradiation. Radiology 108: 205–207

    PubMed  CAS  Google Scholar 

  • Brown JM, Probert JC (1975) Early and late radiation changes following a second course of irradiation. Radiology 115: 711–716

    PubMed  CAS  Google Scholar 

  • Brown JM, Goffinet DR, Cleaver JE, Kallman RF (1971) Preferential radiosensitization of mouse sarcoma relative to normal skin by chronic intraarterial infusion of halogenated pyrimidine analogs. J Natl Cancer Inst 47: 75–89

    PubMed  CAS  Google Scholar 

  • Chu FCH, Conrad JT, Glicksman AS, Nickson JJ (1960) Quantitative and qualitative evaluation of skin erythema. I. Technic of measurement and description of the reaction. Radiology 75: 406–415

    PubMed  CAS  Google Scholar 

  • Cohen L (1966) Radiation response and recovery: radiobiological principles and their relation to clinical practice. In: Schwartz EE, Regato JA del (eds) The biological basis of radiation therapy. Pitman, London

    Google Scholar 

  • Cohen L, Ubaldi SE (1977) Dose-time relationships for postirradiation cutaneous telangiectasia. Int J Radiat Oncol Biol Phys 2: 421–426

    PubMed  CAS  Google Scholar 

  • Cottier H (1966) Histopathologie der Wirkung ionisierender Strahlen auf höhere Organismen (Tier und Mensch). In: Zuppinger A (Hrsg) Strahlenbiologie 2. Handbuch der Medizinischen Radiologie, Bd II/2. Springer, Berlin Heidelberg New York, S 35–272

    Google Scholar 

  • Cram RW, Weder CH, Watson TA (1958) Tolerance of skin grafts to radiation; study of postmastectomy irradiated grafts. Ann Surg 149: 65–67

    Google Scholar 

  • Cronkite EP, Fliedner TM (1972) The radiation syndromes. In: Hug O, Zuppinger A (Hrsg) Strahlenbiologie 3. Handbuch der Medizinischen Radiologie, Bd II/3. Springer, Berlin Heidelberg New York, S 299–340

    Google Scholar 

  • D’Angio GJ, Farber S, Maddock CL (1959) Potentiation of x-ray effects by actinomycin D. Radiology 73: 175–177

    PubMed  Google Scholar 

  • Denekamp J (1973) Changes in the rate of repopulation during multifraction irradiation of mouse skin. Br J Radiol 46: 381–387

    PubMed  CAS  Google Scholar 

  • Denekamp J (1975) Residual radiation damage in mouse skin 5–8 months after irradiation. Radiology 115: 191–195

    PubMed  CAS  Google Scholar 

  • Denekamp J (1977) Early and late radiation reactions in mouse feet. Br J Cancer 36: 322–329

    PubMed  CAS  Google Scholar 

  • Denekamp J, Harris SR (1975) The response of mouse skin to multiple small doses of radiation. In: Alper T (ed) Cell survival after low doses of radiation. Wiley, London

    Google Scholar 

  • Denekamp J, Stewart FA (1979) Evidence for repair capacity in mouse tumours relative to skin. Int J Radiat Oncol Biol Phys 5: 2003–2010

    PubMed  CAS  Google Scholar 

  • Denekamp J, Stewart FA, Douglas BG (1976) Changes in the proliferation rate of mouse epidermis after irradiation: continuous labelling studies. Cell Tissue Kinet 9: 19–29

    PubMed  CAS  Google Scholar 

  • Devik F (1951) Histological and cytological changes produced by oc-particles in the skin of mice. Acta Radiol 35: 149

    Google Scholar 

  • Douglas BG, Fowler JF (1976) The effect of multiple small doses of x-rays on skin reactions in the mouse and a basic interpretation. Radiat Res 66: 401–426

    PubMed  CAS  Google Scholar 

  • Dubrayski N, Hunter N, Withers HR (1976) The effect of precooling on the radiation sensitivity of the proliferating hair follicle. Radiat Res 65: 481–489

    Google Scholar 

  • Durrant KR, Young CMA, Hopewell JW (1977) Effects of variation of overall treatment time on the radiation response of normal human skin. In: Radiobiological research and radiotherapy, vol 1. IAEA, Vienna, pp 21–28

    Google Scholar 

  • Dutreix J, Wambersie A, Bounik C (1973) Cellular recovery in human skin reactions: application to dose, fraction number, overall time relationship in radiotherapy. Eur J Cancer 9: 159–167

    PubMed  CAS  Google Scholar 

  • Ehring F, Honda M (1967) Das Basalzellkarzinom auf röntgenbelasteter Haut. Strahlentherapie 133: 198–207

    PubMed  CAS  Google Scholar 

  • Ellinger F (1957) Medical radiation biology. Thomas, Springfield

    Google Scholar 

  • Ellis F (1969) Dose, time and fractionation: a clinical hypothesis. Clin Radiol 20: 1–7

    PubMed  CAS  Google Scholar 

  • Ellis F, Sorenson A, Lescrenier C (1974) Radiation therapy schedules for opposing parallel fields and their biological effects. Radiology 111: 701–707

    PubMed  CAS  Google Scholar 

  • Essen CF von (1963) A spatial model of time-dosearea relationship in radiation therapy. Radiology 81: 881–883

    Google Scholar 

  • Essen CF von (1972) Clinical radiation tolerance of the skin and upper aerodigestiv tract. Front Radiat Ther Oncol 6: 148–159

    Google Scholar 

  • Fajardo LF, Berthrong M (1981) Radiation injury in surgical pathology. III Salivary glands, pancreas and skin. Am J Surg Pathol 5: 279–296

    PubMed  CAS  Google Scholar 

  • Fertil B, Malaise EP (1981) Inherent cellular radio-sensitivity as a basic concept for human tumor radiotherapy. Int J Radiat Oncol Biol Phys 7: 621–629

    PubMed  CAS  Google Scholar 

  • Field SB (1969) Early and late reactions in skin of rats following irradiation with X-rays or fast neutrons. Radiology 92: 381–384

    PubMed  CAS  Google Scholar 

  • Field SB (1972) The Ellis formula for x-rays and fast neutrons. Br J Radiol 45: 315–317

    PubMed  CAS  Google Scholar 

  • Field SB (1976) An historical survey of radiobiology and radiotherapy with fast neutrons. Curr Top Radiat Res 11: 1–86

    CAS  Google Scholar 

  • Field SB, Law MP (1976) The relationship between early and late radiation damage in rodent skin. Int J Radiat Biol 30: 557–564

    CAS  Google Scholar 

  • Field SB, Michalowski A (1979) Endpoints for damage to normal tissues. Int J Radiat Oncol Biol Phys 5: 1185–1196

    PubMed  CAS  Google Scholar 

  • Field SB, Morgan RL, Morrison R (1976) The response of human skin to irradiation with x-rays or fast neutrons. Int J Radiat Oncol Biol Phys 1: 481–486

    PubMed  CAS  Google Scholar 

  • Fowler JF, Morgan RL, Silvester JA, Bewley DK, Turner BA (1963) Experiments with fractionated X-ray treatment of the skin of pigs. I-Fractionation up to 28 days. Br J Radiol 36: 188–196

    PubMed  CAS  Google Scholar 

  • Fowler JF, Bewley DK, Morgan RL (1965a) Experiments with fractionated x-irradiation of the skin of pigs. II. Fractionation up to five days. Br J Radiol 38: 278–284

    CAS  Google Scholar 

  • Fowler JF, Kragt K, Ellis RE, Lindop PJ, Berry RJ (1965b) The effect of divided doses of 15 MeV electrons on the skin response of mice. Int J Radiat Biol 9: 241–252

    Google Scholar 

  • Frommhold W, Bublitz G (1967) Untersuchungen über Unterhautfibrosen nach Telkobalttherapie und ihre Behandlungsmöglichkeiten mit DMSO. Strahlentherapie 133: 529–538

    PubMed  CAS  Google Scholar 

  • Gassmann A (1899) Zur Histologie der Röntgenulcera. Fortschr Roentgenstr 2: 199–207

    Google Scholar 

  • Gauwerky F, Langheim F (1978) Der Zeitfaktor bei der strahleninduzierten subkutanen Fibrose. Strahlentherapie 154: 608–616

    PubMed  CAS  Google Scholar 

  • Glasser O (1925) Erythemdosen in Röntgeneinheiten. Strahlentherapie 20: 141–144

    Google Scholar 

  • Glicksman AS, Chu FCH, Bane HN, Nickson JJ (1960) Quantitative and qualitative evaluation of skin erythema. II. Clinical study in patients on a standardised irradiation schedule. Radiology 75: 411–415

    PubMed  CAS  Google Scholar 

  • Greco FA, Brereton HD, Kent H, Zimbler H, Merrill J, Johnson RE (1976) Adriamycin and enhanced radiation reaction in normal esophagus and skin. Ann Intern Med 85: 294–298

    PubMed  CAS  Google Scholar 

  • Gremmel H, Kellerer AM, Wendhausen H (1979) Ergänzungen zu den Grundlagen und Anwendungen der Ellis-Formel. Strahlenbiologie 155: 328–331

    CAS  Google Scholar 

  • Griem ML, Malkinson FD (1967) Some studies on the effects of radiation and radiation modifiers on growing hair. Radiat Res 30: 431–443

    PubMed  CAS  Google Scholar 

  • Griem ML, Dimitrievich GS, Lee RM (1979) The effects of X-irradiation and adriamycin on proliferating and non-proliferating hair coat of the mouse. Int J Radiat Oncol 5: 1261–1264

    CAS  Google Scholar 

  • Grise JW, Rubin P, Ryplansky A, Cramer L (1960) Factors influencing response and recovery of grafted skin to ionizing irradiation; experimental observations. Am J Roentgenol 83: 1087–1096

    CAS  Google Scholar 

  • Guigon M, Frindel E, Tubiana M (1978) Effects of the association of chemotherapy and radiotherapy on normal mouse skin. Int J Radiat Oncol Biol Phys 4: 233–238

    PubMed  CAS  Google Scholar 

  • Hayashi S, Suit HD (1972) Effect of fractionation radiation dose on skin contraction and skin reaction of Swiss mice. Radiology 103: 431–437

    PubMed  CAS  Google Scholar 

  • Heidenhain L (1926) Das Problem der Röntgendosis. Strahlentherapie 21: 96–109

    Google Scholar 

  • Heineke H, Perthes G (1925) Die biologische Wirkung der Röntgen-und Radiumstrahlen. In: Meyer H (Hrsg) Lehrbuch der Strahlentherapie, Bd 1. Urban & Schwarzenberg, Berlin Wien, S 725–882

    Google Scholar 

  • Hendry JH, Rosenberg I, Greene D (1977) Re-irradiation of rat tails to necrosis at six months after treatment with a „tolerance“ dose of x-rays or neutrons. Br J Radiol 50: 567–572

    PubMed  CAS  Google Scholar 

  • Herrmann T, Voigtmann L (1979) Zur klinischen Anwendbarkeit des NSD-Konzeptes.–Möglichkeiten und Grenzen. Radiobiol Radiother 20: 51–63

    CAS  Google Scholar 

  • Holthusen H (1925) Die qualitative und quantitative Messung der Röntgenstrahlen. In: Meyer H (Hrsg) Lehrbuch der Strahlentherapie, Bd 1. Urban & Schwarzenberg, Berlin Wien, S 287–360

    Google Scholar 

  • Holthusen H (1936) Erfahrungen über die Verträglichkeitsgrenze für Röntgenstrahlen und deren Nutzanwendung zur Verhütung von Schäden. Strahlentherapie 57: 254–269

    Google Scholar 

  • Hopewell JW (1980) The importance of vascular damage in the development of late radiation effects in normal tissues. In: Meyn RE, Withers HR (eds) Radiation biology in cancer research, Raven, NY, pp 449–459

    Google Scholar 

  • Hopewell JW, Gunn Y (1981) Factors for correcting the CRE formula for late effects in normal tissues: how valid are they? Int J Radiat Oncol Biol Phys 7: 683–684

    PubMed  CAS  Google Scholar 

  • Hopewell JW, Young CMA (1982) The effect of field size on the reaction of pig skin to single doses of X-rays. Br J Radiol 55: 356–361

    PubMed  CAS  Google Scholar 

  • Hopewell JW, Foster JL, Genn Y (1978) Role of vascular damage in the development of late radiation effects in the skin, pp 483–492 in Late Biological Effects of Ionizing Radiation. Proceeding of a Symposium, Vienna, March 1978. International Atomic Energy Agency publication STI/ PUB/489, Vienna

    Google Scholar 

  • Hopewell JW, Foster JL, Young CMA, Wiernik G (1979) Late radiation damage to the pig skin. Radiology 130: 783–788

    PubMed  CAS  Google Scholar 

  • Hug O (1974) Medizinische Strahlenkunde. Urban & Schwarzenberg, München

    Google Scholar 

  • Hug O, Kellerer AM, Zuppinger A (1966) Der Zeitfaktor. In: Hug O, Zuppinger A (Hrsg) Strahlenbiologie 1. Handbuch der Medizinischen Radiologie, Bd II/1. Springer, Berlin Heidelberg New York, S 271–354

    Google Scholar 

  • Hunter RD, Stewart JG (1977) The tolerance to re-irradiation of heavily irradiated human skin. Br J Radiol 50: 573–575

    PubMed  CAS  Google Scholar 

  • Iselin H (1912) Schädigung der Haut durch Röntgenlicht nach Tiefenbestrahlung (Aluminium). Kumulierende Wirkung. Munch Med Wochenschr 59: 2660–2663

    Google Scholar 

  • Jolles B, Harrison RG (1966) Enzymatic processes and vascular changes in the skin irradiation reaction. Br J Radiol 39: 12

    PubMed  CAS  Google Scholar 

  • Jolles B, Mitchell RG (1947) Optimal skin tolerance dose levels. Br J Radiol 20: 405–409

    PubMed  CAS  Google Scholar 

  • Joyet G, Hohl K (1955) Die biologische Hautreaktion in der Tiefentherapie als Funktion der Feldgröße. Ein Gesetz der Strahlentherapie. Fortschr Roentgenstr 82: 387–400

    CAS  Google Scholar 

  • Kärcher KH (1958) Über die Nachbehandlung strahlenbelasteter Haut. Strahlentherapie 107: 453–461

    PubMed  Google Scholar 

  • Kärcher KH (1963) In: Scherer E, Stender HS (Hrsg) Strahlenpathologie der Zelle. Thieme, Stuttgart, S 317–333

    Google Scholar 

  • Kal HB (1974) Response of a rat rhabdomyosarcoma and rat skin to irradiation with gamma rays and 15 MeV neutrons at low dose rates. Radiobiological Institute, TNO, Rijswijk

    Google Scholar 

  • Kalz F (1941) Theoretical considerations and clinical use of Grenz rays in dermatology. Arch Dermatol Syph 43: 447–472

    Google Scholar 

  • Kellerer AM (1977) Grundlagen der Ellis-Formel. Strahlentherapie 153: 384–392

    PubMed  CAS  Google Scholar 

  • Klostermann GF (1966) Röntgenfolgen an der Haut nach Hämangiombestrahlung. Strahlentherapie: 130: 205–218

    PubMed  CAS  Google Scholar 

  • Kirk J, Gray WM, Watson ER (1971) Cumulative radiation effect. Part I. Fractionated treatment regimes. Clin Radiol 22: 145

    PubMed  CAS  Google Scholar 

  • Kirk J, Gray WM, Watson R (1972) Cumulative radiation effect-II: Continuous radiation therapy - long-lived sources. Clin Radiol 23: 93–105

    PubMed  CAS  Google Scholar 

  • Law MP (1981) Radiation-induced vascular injury and its relation to late effects in normal tissues. Adv Radiat Biol 9: 37–73

    CAS  Google Scholar 

  • Law MP Thomlinson RH (1978) Vascular permeability in the ear of rats after X-irradiation. Br J Radiol 51: 895–904

    PubMed  CAS  Google Scholar 

  • Law MP, Ahier RG, Field SB (1977) The response of mouse skin to combined hyperthermia and x-rays. Int J Radiat Biol 32: 153–163

    CAS  Google Scholar 

  • Lemperle G, Koslowski J (Hrsg) (1984) Chirurgie der Strahlenfolgen. Urban & Schwarzenberg, München

    Google Scholar 

  • Liegner LM, Michaud NJ (1961) Skin and subcutaneous reactions induced by supervoltage irradiation. Am J Roentgenol 85: 533–549

    CAS  Google Scholar 

  • Linden WA (1972) Die relative biologische Wirksamkeit der Hochvoltstrahlen in der Strahlentherapie. Strahlentherapie 144: 679–690

    PubMed  CAS  Google Scholar 

  • Liversage WE (1969) A general formula for equating protracted and acute regimes of radiation. Br J Radiol 42: 432–440

    PubMed  CAS  Google Scholar 

  • Markus B, Schlotfeldt D (1966) Gibt es ein spezifisches Elektronenerythem? Experimentelle Untersuchungen mit schnellen Elektronen und Röntgenstrahlen. Strahlentherapie 132: 206–227

    Google Scholar 

  • Masuda K, Hunter N, Withers HP (1980) Late effect in mouse skin following single and multifractionated irradiation. Int J Radiat Oncol Biol Phys 6: 1539–1544

    PubMed  CAS  Google Scholar 

  • Miescher G (1924) Das Röntgenerythem. Strahlentherapie 16: 333–371

    Google Scholar 

  • Morris GM, Hopewell JW (1980) The effects of fractionated X-ray irradiation on the kinetics of the epithelial basal cell population in pig skin. In: Report of the Research Institute Churchill Hospital, Oxford

    Google Scholar 

  • Moulder JE, Fisher JJ, Casey A (1975) Dose-time relationship for skin reactions and structural damage in rat feet exposed to 250 kV X-rays. Radiology 115: 466–470

    Google Scholar 

  • Moustafa HF, Hopewell JW (1979) Blood flow clearance changes in pig skin after single doses of x-rays. Br J Radiol 52: 138–144

    PubMed  CAS  Google Scholar 

  • Muggia FM, Cortes-Funes H, Wassermann TH (1978) Radiotherapy and chemotherapy in combined clinical trials: problems and promise. Int J Radiat Oncol Biol Phys 4: 161–171

    PubMed  CAS  Google Scholar 

  • Mühlmann E, Meyer O (1923) Beiträge zur Röntgenschädigung tiefgelegener Gewebe. Strahlentherapie 15: 48–64

    Google Scholar 

  • Nias AHW (1963) Some comparisons of fractionation effects in erythema measurements on human skin. Br J Radiol 36: 183–187

    PubMed  CAS  Google Scholar 

  • Notter G, Turesson I (1976) Prospective studies with the CRE formula of prolonged fractionation schedules. Radiology 121: 709–715

    PubMed  CAS  Google Scholar 

  • Orton CG (1974) Time-dose factors (TDF’s) in brachytherapy. Br J Radiol 47: 603–607

    PubMed  CAS  Google Scholar 

  • Orton CG, Ellis F (1973) A simplification in the use of the NSD concept in practical radiotherapy. Br J Radiol 46: 529–537

    PubMed  CAS  Google Scholar 

  • Patterson TJS, Berry RJ, Wiernik G (1972) The effect of x-radiation on the survival of skin flaps in the pig. Br J Plast Surg 25: 17–19

    PubMed  CAS  Google Scholar 

  • Patterson TJS, Berry RJ, Hopewell JW, Wiernik G (1975) The effect of x-radiation on the survival of experimental skin flaps. In: Grabb WC, Myers MB (eds) Skin flaps. Little, Brown and Company, Boston, pp 39–46

    Google Scholar 

  • Peel DM, Hansen LS, Coggle JE, Hopewell JW, Charles MW, Wells J (1982) Non-stochastic effects of different energy beta emitters on pig and mouse skin. In: Proc Intern Congr Radiat Protect Inverness

    Google Scholar 

  • Peters U, Withers HR (1981) Factors for correcting the CRE formula for late effects in normal tissues: how valid are they? Int J Radiat Oncol Biol Phys 7: 684–685

    PubMed  CAS  Google Scholar 

  • Phillips TL (1980) Tissue toxicity of radiation-drug interaction. In: Sokol GH, Maickel RP (eds) Radiation-drug interactions in the treatment of cancer. Wiley, New York Chichester Brisbane Toronto, pp 175–200

    Google Scholar 

  • Potten CS (1978) The cellular and tissue response to single doses of ionizing radiation. In: Current topics in radiation research 13: 1–59

    Google Scholar 

  • Powell-Smith C (1965) Factors influencing the incidence of radiation injury in cancer of the cervix. J Ass Canad Radiol 16: 132–137

    Google Scholar 

  • Probert JC, Brown MA (1974) A comparison of 3 and 5 times weekly fractionation on the response of normal and malignant tissues of the C3H mouse. Br J Radiol 47: 775–780

    PubMed  CAS  Google Scholar 

  • Redpath JL, Colman M (1979) The effect of adriamycin and actinomycin D on radiation-induced skin reactions in mouse feet. Int J Radiat Oncol Biol Phys 5: 483–486

    PubMed  CAS  Google Scholar 

  • Reinhold HS, Buisman GH (1973) Radiosensitivity of capillary endothelium. Br J Radiol 46: 54–57

    PubMed  CAS  Google Scholar 

  • Reinhold HS, Buisman GH (1975) Repair of radiation damage to capillary endothelium. Br J Radiol 48: 727–731

    PubMed  CAS  Google Scholar 

  • Reisner A (1933) Hauterythem und Röntgenstrah- lung. Ergeb Med Strahlenforschung 6: 1–60

    Google Scholar 

  • Renner Kh, Renner H (1971) Experimentelle Untersuchungen über das Auftreten und den Verlauf des Früherythems an der Schweinehaut. Strahlentherapie 142: 219–226

    PubMed  CAS  Google Scholar 

  • Rubin P, Casarett GW (1968) Clinical radiation pathology. Saunders, Philadelphia London Toronto

    Google Scholar 

  • Rubin P, Grise JW (1960) The difference in response of grafted and normal skin to ionizing radiations. Am J Roentgenol 84: 645–655

    CAS  Google Scholar 

  • Rubin P, Casarett G, Grise JW (1960) The vascular pathophysiology of an irradiated graft. Am J Roentgenol 83: 1097–1104

    CAS  Google Scholar 

  • Sause WT, Stewart JR, Plenk HP, Levitt DD (1981) Late skin changes following twice-weekly electron beam radiation to post-mastectomy chest walls. Int J Radiat Oncol 7: 1541–1544

    CAS  Google Scholar 

  • Seitz L, Wintz H (1920) Unsere Methode der Röntgentiefentherapie und ihre Erfolge. Sonderband 5 der Strahlentherapie

    Google Scholar 

  • Sheline GE, Phillips TL, Brennan SB (1971) Effects of fast neutrons on human skin. Am J Roentgenol 111: 31–41

    CAS  Google Scholar 

  • Smith KC, Hahn GM, Hoppe RT, Earle JD (1980) Radiosensitivity in vitro of human fibroblasts derived from patients with a severe skin reaction to radiation therapy. Int J Radiat Oncol Biol Phys 6: 1573–1575

    PubMed  CAS  Google Scholar 

  • Stein G (1963) Röntgenfolgezustände im Bereich der Haut. Strahlentherapie 121: 247–258

    PubMed  CAS  Google Scholar 

  • Strandquist M (1944) Studien über die kumulative Wirkung der Röntgenstrahlen bei Fraktionierung. Acta Radiol [Suppl] 55: 1–300

    Google Scholar 

  • Strauß O (1925) Schädigungen durch Röntgen-und Radiumstrahlen. In: Meyer H (Hrsg) Lehrbuch der Strahlentherapie, Bd I. Urban & Schwarzenberg, Berlin Wien, S 979–1060

    Google Scholar 

  • Tannock IF, Hayashi S (1972) The proliferation of capillary endothelial cells. Cancer Res 32: 77–82

    PubMed  CAS  Google Scholar 

  • Trott KR (1972) Strahlenwirkungen auf die Vermehrung von Säugetierzellen. In: Hug O, Zuppinger A (Hrsg) Strahlenbiologie 3. Handbuch der Medizinischen Radiologie, Bd II/3. Springer, Berlin Heidelberg New York, S 43–125

    Google Scholar 

  • Trott KR (1982) Experimental results and clinical implications of the four „r“ in fractionated radiotherapy. Radiat Environ Biophys 20: 159–170

    PubMed  CAS  Google Scholar 

  • Trott KR, Kummermehr J (1982) Split dose recovery of a mouse tumour and its stroma during fractionated irradiation. Br J Radiol 55: 841–846

    PubMed  CAS  Google Scholar 

  • Turesson I, Notter G (1976) Control of dose administered once a week and three times a day according to schedules calculated by CRE formula, using skin reaction as a biological parameter. Radiology 120: 399–404

    PubMed  CAS  Google Scholar 

  • Turesson I, Notter G (1979a) The response of pig skin to single and fractionated high dose rate and continuous low dose rate 137Cs-irradiation. I. Experimental design and results. Int J Radiat Oncol Biol Phys 5: 835–844

    PubMed  CAS  Google Scholar 

  • Turesson I, Notter G (1979b) The response of pig skin to single and fractionated high dose-rate and continuous low dose-rate 137Cs-irradiation. III Re-evaluation of the CRE system and the TDF system according to the present findings. Int J Radiat Oncol Biol Phys 5: 1773–1779

    PubMed  CAS  Google Scholar 

  • Ullrich RL, Casarett GW (1977) Interrelationship between the early inflammatory response and subsequent fibrosis after radiation exposure. Radiat Res 72: 107–121

    PubMed  CAS  Google Scholar 

  • Voigtmann L, Ehrhardt M, Strietzel M, Eberhardt HJ, Herrmann T (1979) Probleme bei der Applikation von Stehfeldbestrahlungsmethoden in der Telekobalttherapie 2. Mitt. Anwendung des NSD-Konzeptes für die Beurteilung von Fraktionierungsmethoden zur Senkung des Rüstzeitaufwandes. Radiobiol Radiother 20: 64–78

    CAS  Google Scholar 

  • Weichselbaum RR, Epstein J, Little JB (1976) In vitro radiosensitivity of human diploid fibroblasts derived from patients with unusual clinical responses to radiation. Radiology 121: 479–482

    PubMed  CAS  Google Scholar 

  • White RL, El-Mandi AM, Ramirez HL (1975) Thermographie changes following preoperative radiotherapy in head and neck cancer. Radiology 117: 469–471

    PubMed  CAS  Google Scholar 

  • Wiernik G, Patterson TJS, Berry RJ (1974) The effect of fractionated dose-patterns of x-radiation on the survival of experimental skin flaps in the pig. Br J Radio! 47: 343–345

    CAS  Google Scholar 

  • Withers HR (1975) The four R’s of radiotherapy. In: Lett JT, Adler H (eds) Advances in radiation biology, Bd 5. Academic Press, New York, pp 241–271

    Google Scholar 

  • Withers HR (1981) Differences in the fractionation response of acute and late responding tissues. In: Kärcher KH, Kogelnik HD, Reinartz G (eds) Proceedings of the Second International Meeting in Radio-Oncology. Raven, New York

    Google Scholar 

  • Withers HR, Flow BL, Huchton UI, Hussey DH, Jardine JH, Mason KA, Rauston GL, Smathers JB (1977) Effect of dose fractionation on early and late skin responses to y-rays and neutrons. Int J Radiat Oncol Biol Phys 3: 227–233

    PubMed  CAS  Google Scholar 

  • Withers HR, Thames HD, Flow BL, Mason KA, Hussey DH (1978a) The relationship of acute and late skin injury in 2 and 5 fractions/week y-ray therapy. Int J Radiat Oncol Biol Phys 4: 595–601

    CAS  Google Scholar 

  • Withers HW, Thames HD, Hussey DH, Flow BL, Mason KA (1978b) Relative biological effectiveness (RBE) of 50 MV ( Be) neutrons for acute and late skin injury. Int J Radiat Oncol Biol Phys 4: 603–608

    CAS  Google Scholar 

  • Young CMA, Hopewell JW (1980) Annual report of the research institute. Churchill Hospital, Oxford, pp 48–55

    Google Scholar 

  • Young CMA, Hopewell JW (1983) The effects of pre-operative X-irradiation on the survival and blood flow of pedicle skin flaps in the pig. Int J Radiat Oncol Biol Phys 9: 865–870

    PubMed  CAS  Google Scholar 

  • Zollinger HJ (1960) Radiohistologie und Radio Histopathologie. In: Roulet F (Hrsg) Strahlung und Wetter. Handbuch der allgem Pathologie, Bd X/1. Springer, Berlin Heidelberg New York, S 127–287

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Trott, KR., Kummermehr, J. (1985). Strahlenwirkungen auf die Haut. In: Heuck, F., Scherer, E. (eds) Strahlengefahrdung und Strahlenschutz / Radiation Exposure and Radiation Protection. Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82229-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-82229-2_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82230-8

  • Online ISBN: 978-3-642-82229-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics