Abstract
There has probably never been a method which has been so widely applicable in the field of in-vitro diagnosis as radioimmunoassay or its variations. The use of the antigen-antibody reaction with its specificity, coupled with the use of radioactive ligands, has led to sensitive methods which now form a routine part of laboratory in-vitro diagnostic programmes. In nuclear medicine in its classical sense, the best example of the combination of in-vivo and in-vitro methods using radioactive tracers is in the field of thyroid disorders.
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References
a) Milestones in radioligand assays
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Wood, W.G. (1985). In Vitro Diagnosis in the Nuclear Medical Laboratory. In: Hundeshagen, H. (eds) Nuklearmedizin / Nuclear Medicine. Handbuch der medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 15 / 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82225-4_2
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