Skip to main content
SpringerLink
Log in

Role of Radiotherapy

  • Chapter
Lung Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 92))

  • 65 Accesses

Abstract

When high energy X-ray equipment was developed to produce sufficiently penetrating beams to treat deep-seated intrathoracic tumours, it became evident that regression of lung cancers could be achieved. For the majority of patients radiotherapy provided only a short remission of symptoms produced by local compression or infiltration of intrathoracic structures by tumour. In 1956 however Smart and Hilton reported on 40 highly selected cases of whom nine (22.5%) survived 5 years. Since than there have been many reports confirming that 2%–10% of patients with inoperable lung cancer can be cured by radiotherapy. With such a small cure rate in a very common condition it is especially important to identify as carefully as possible those patients who are most likely to benefit from treatment and the most effective way of delivering it.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abadir R, Muggia FM (1975) Irradiated lung cancer — An autopsy analysis of spread pattern. Radiology 114: 427–430

    PubMed  CAS  Google Scholar 

  • Abramson N, Cavanaugh PJ (1973) Short-course radiation therapy in carcinoma of the lung. Radiology 108: 685–687

    PubMed  CAS  Google Scholar 

  • Beling U, Einhorn J (1965) Radiotherapy for carcinoma of the lung. Acta Radiol 3: 281–286

    Article  CAS  Google Scholar 

  • Bloedorn FG, Cowley RA, Cuccia CA et al. (1964) Pre-operative radiation in bronchogenic carcinoma. AIR 92: 77–87

    CAS  Google Scholar 

  • Bromley LL, Szur L (1955) Combined radiotherapy and resection for carcinoma of the bronchus: Experiences with 66 patients. Lancet 2: 937–941

    Article  Google Scholar 

  • Caldwell WL, Bagshawe MA (1968) Indications for and results of irradiation of carcinoma of the lung. Cancer 22: 999–1004

    Article  PubMed  CAS  Google Scholar 

  • Cox JD, Eisert DR, Komaki R et al. (1979) Patterns of failure following treatment of apparently localised carcinoma of the lung. Ìn: Muggia F, Rosencweig M (eds) Lung cancer: Progress in therapeutic research. Raven, New York, pp 279–288

    Google Scholar 

  • Coy P, Kennelly GM (1980) The role of curative radiotherapy in the treatment of lung cancer. Cancer 45: 698–702

    Article  PubMed  CAS  Google Scholar 

  • Deeley TM, Singh SP (1967) Treatment of inoperable carcionmas of the bronchus by megavoltage X-rays. Thorax 22: 562–566

    Article  PubMed  CAS  Google Scholar 

  • Emami B, Melo A, Carter BL, Munzenrider JE, Piro AJ (1978) Value of computed tomography in radiotherapy of lung cancer. AJR 131: 63–67

    PubMed  CAS  Google Scholar 

  • Eichhorn H-J (1982) Results of a pilot study on neutron therapy with 600 patients. Int J Radiat Oncol Biol Phys 8 /9: 1561–1565

    Article  PubMed  CAS  Google Scholar 

  • Guttman RJ (1971) Radical supervoltage therapy in inoperable carcinoma of the lung. In: Deeley TJ

    Google Scholar 

  • ed) Modern radiotherapy carcinoma of the bronchus. Butterworths, London, pp 181–195

    Google Scholar 

  • Hilaris B, Martini M (1971) Interstitial brachytherapy in cancer of the lung: A 20 year experience. Int J Radiat Oncol Biol Phys 5: 1951–1956

    Google Scholar 

  • Hobday PA, Hodson NJ, Husband JE et al. (1980) Changes in treatment plans resulting from CT scan localisations. Br J Radiol [Suppl] 15: 103–106

    Google Scholar 

  • Holsti L, Vuorinen P (1967) Radiation reaction in the lung after continuous and split course megavoltage radiotherapy of lung cancer. Br J Radiol 40: 280–284

    Article  PubMed  CAS  Google Scholar 

  • Lee RE (1974) Radiotherapy of bronchogenic carcinoma. Semin Oncol 1, 3: 245–251

    PubMed  CAS  Google Scholar 

  • Levitt SH, Bogardus CR, Ladd G (1967) Split dose intensive radiation therapy in the treatment of advanced lung cancer. Radiology 88: 1159–1161

    PubMed  CAS  Google Scholar 

  • McEwen JB (1971) Methods of improving results of radiation. IV. Hyperbaric oxygen. In: Deeley TJ (ed) Modern radiotherapy carcinoma of the bronchus. Butterworths, London, pp 241–245

    Google Scholar 

  • Moise TS (1921) Primary carcinoma of the lungs Arch Intern Med 28: 733–772

    Google Scholar 

  • Morrison R, Deeley TJ, Cleland WP (1963) The treatment of carcinoma of the bronchus. A clinical trial to compare surgery and supervoltage radiotherapy. Lancet 1: 683–684

    Google Scholar 

  • Neeley JM (1925) Primary carcinoma of the lung: a pathological and clinical study based on 80 cases. Nebr Med J 20: 693–695

    Google Scholar 

  • Perez CA, Stanley K, Robin P et al. (1980) A prospective randomised study of various irradiation doses and fractionation schedules in the treatment of inoperable non-oat-cell carcinoma of the lung. Cancer 45: 2744–2753

    Article  PubMed  CAS  Google Scholar 

  • Perez CA, Stanley K, Grundy G et al. (1982) Impact of irradiation technique and tumour extent on tumour control and survival of patients with unresectable non oat cell carcinoma of the lung. Cancer 50: 1091–1099

    Article  PubMed  CAS  Google Scholar 

  • Perez-Tamayo R, Soberon M (1969) The place of radiotherapy in the treatment of bronchogenic carcinoma. Mo Med 66: 876–880

    PubMed  CAS  Google Scholar 

  • Pierquin B, Gravis P, Gelle X (1965) Etude de 688 cas de cancers bronchiques traités par teleradio therapie (200 kV et 22 MV). J Radiol 46: 201–216

    CAS  Google Scholar 

  • Rissanen PM, Tikka U, Holsti LR (1968) Autopsy findings in lung cancer treated with megavoltage radiotherapy. Acta Radiol Oncol Radiat Phys Biol 7: 433–442

    CAS  Google Scholar 

  • Rogers WL (1932) Primary cancer of the lung: a clinical and pathological survey of 327 cases. Arch Intern Med 49: 1058–1077

    Article  Google Scholar 

  • Rubin P (ed) (1975) Radiation biology and pathology Syllabus. American College of Radiology, Chicago, pp 132–141

    Google Scholar 

  • Salazar OM (1979) Tumour contol and radiation toxicity in the treatment of lung cancer: An analysis of time-dose-volume factors. In’ Muggia F, Rosencweig M (eds) Lung cancer: Progress in therapeutic research. Raven, New York, pp 267–278

    Google Scholar 

  • Salazar OM, Rubin P, Brown JC et al. (1976) Predictors of radiation response in lung cancer. A clinico-pathological analysis. Cancer 37: 2636–2650

    Google Scholar 

  • Saunders MI, Anderson P, Dische S et al. (1982) A controlled clinical trial of misonidazole in the radiotherapy of patients with carcinoma of the bronchus. Int J Radiat Oncol Biol Phys 8 /9: 347–350

    PubMed  CAS  Google Scholar 

  • Seydel GH, Kutcher GJ, Steiner RM et al. (1980) Computed tomography in planning radiation therapy for bronchogenic carcinoma. Int J Radiat Oncol Biol Phys 6: 601–606

    PubMed  CAS  Google Scholar 

  • Shields TW, Higgins GA, Lawton R et al. (1970) Pre-operative X-ray therapy as an adjuvant in the treatment of bronchogenic carcinoma. J Thorac Cardiovasc Surg 59: 49–61

    PubMed  CAS  Google Scholar 

  • Smart J, Hilton G (1956) Radiotherapy of cancer of the lung: results in a selected group of cases. Lancet 270: 880–882

    Article  PubMed  CAS  Google Scholar 

  • Stanley KE (1980) Prognostic factors for survival in patients with inoperable lung cancer. J Natl Cancer Inst 65: 25–32

    PubMed  CAS  Google Scholar 

  • Stewart JR, Cohn KE, Fagarido LF et al. (1967) Radiation induced heart disease, a study of twenty-five patients. Radiology 89: 302–310

    Google Scholar 

  • Van Houtte P, Piron A, Lustman-Maréchal J, Osteaux M, Henry J (1980) Computed axial tomographiy ( CAT) contribution for dosimetry and treatment evaluation in lung cancer. Int J Radiat Oncol Biol Phys 6: 995–1000

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiotherapy and Oncology, Cookridge Hospital, Leeds, LS16 6QB, Great Britain

    D. Ash

Authors
  1. D. Ash
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Clinical Oncology, Western General Hospital, Crewe Road, EH4 2XU, Edinburgh, UK

    William Duncan

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Ash, D. (1984). Role of Radiotherapy. In: Duncan, W. (eds) Lung Cancer. Recent Results in Cancer Research, vol 92. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82218-6_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-82218-6_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82220-9

  • Online ISBN: 978-3-642-82218-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation