Zusammenfassung
Zwölf Jahre Chemotherapie bei malignen Melanomen haben, beginnend am Punkte Null, zweifellos beachtenswerte Fortschritte gebracht, aber das Gesamtergebnis kann nicht zufriedenstellen. Allenfalls bei einem Drittel aller Behandelten werden meßbare Remissionen erzielt, die zudem in Bezug auf die reduzierte Tumormasse unzureichend und im Hinblick auf die Remissionszeit eng begrenzt sind. Das ideale Therapieziel, nämlich Heilung, ist bisher in keinem einzigen dokumentierten Falle erreicht worden.
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Literatur
Ahn SS, Morton DL (1982) Preliminary results of BOLD for disseminated melanoma. Proc Am Soc Clin Oncol 1:179
Byrne MJ, Reynolds PM (1982) Phase-II-study of cyclophosphamide, vincristine and DTIC + BCG in the treatment of malignant melanoma. Austr NZ J med 12:263
Costanzi JJ, Al-Sarraf M, Frank J (1982) Chemoimmunotherapy in disseminated melanoma: A southwest oncology group study. Proc Am Soc Clin Oncol 1:169
Costanzi JJ (1983) The chemotherapy of human malignant melanoma. In: Costanzi JJ (ed) Malignant melanoma I. Martinus Nijhoff, The Hague Boston London, pp 259–274
Mulder JH, Dodion P, Cavalli F, Czarnetzki B, Clavel M, Thomas D, Suciu S, Rosencweig M (1982) Cisplatin and Vindesine combination chemotherapy in advanced malignant melanoma: an EORTC-phase-II-study. Eur J Cancer Clin Oncol 18:1297
Neifeld JP, Tormey DC, Baker A, Meyskens Jr FL, Taub RN (1982) Phase-II-trial of a dopaminergic inhibitor in previously treated melanoma patients. Proc Am Soc Clin Oncol 1:170
Priestman TJ (1983) Krebs-Chemotherapie. Zuckschwerdt, München, S 12
Reimer RR, Gahbauer R, Bukowski RM, Hewlett JS, Groppe Jr CW, Weick JK, Antunez AR (1981) Simultaneous treatment with Cisplatin and radiation therapy for advanced solid tumors: A pilot study. Cancer Treat Rep 65:219
Rumke P, Israels SP (1982) DNCB-DTIC for skin metastases. Reported at the EORTC Melanoma Group Meeting, Glasgow, Oct 29–30
Rumke P (1982) Tamoxifen in post-menopausal women. Reported at the EORTC Melanoma Group Meeting, Glasgow, Oct 29–30. Accepted protocol no 18831
Skipper HE, Schabel FM, Wilcox WS (1964) Experimental evaluation of potential cancer agents. XIII. On the criteria and kinetics associated with “curability” of experimental leukemia. Cancer Chemother Rep 35:3
Veronesi U, Adamus J, Aubert C, Bajetta E, Beretta G, Bonadonna G, Bufalino R, Cascinelli N, Cocconi G, Durand J, De Marsillac J, Ikonopisov RL, Kiss B, Lejeune F, MacKie R, Madej G, Mulder H, Mechl Z, Milton GW, Morabito A, Peter H, Priario J, Paul E, Rumke P, Sertoli R, Tomin R (1982) A randomized trial of adjuvant chemotherapy and immunotherapy in cutaneous melanoma. N Engl J Med 307:913
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© 1983 Springer-Verlag Berlin Heidelberg
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Macher, E. (1983). Chemotherapie bei malignen Melanomen. In: Braun-Falco, O., Burg, G. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82207-0_38
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DOI: https://doi.org/10.1007/978-3-642-82207-0_38
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