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Estrogen and Progesterone Receptors as Prognostic Factors in Early Breast Cancer

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Clinical Interest of Steroid Hormone Receptors in Breast Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 91))

Abstract

During the past 10 years, steroid receptors in human breast tumors have been extensively investigated in many laboratories. The initial aim of this clinical research was to help in selecting patients with metastasis for hormonal treatment.

This work was supported in part by the Institut National de la Santé et de la Recherche Médicale (ATP 24-75-47) and CRAT (76-4-490) and the Fédération Française des Centres de Lutte contre le Cancer

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References

  1. Allegra JC, Lippman ME, Thompson EB, Simon A, Barlock A, Green L, Huff KK, Do HM, Aitken SC (1979) Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer. Cancer Res 39: 1447–1454

    PubMed  CAS  Google Scholar 

  2. Dao TL, Nemoto T (1980) Steroid receptors and response to endocrine ablation in women with metastatic cancer of the breast. Cancer 46: 2779–2782

    Article  PubMed  CAS  Google Scholar 

  3. Hilf R, Feldstein ML, Gibson SL, Savlon ED (1980) The relative importance of estrogen receptor analysis as a prognostic factor for recurrence or response to chemotherapy in women with breast cancer. Cancer 45: 1993–2000

    Article  PubMed  CAS  Google Scholar 

  4. Horwitz K, McGuire WL (1978) Estrogen control of progesterone receptors in human breast cancer. J Biol Chem 253: 2273–2278

    Google Scholar 

  5. Huggins L, Grand CC, Brillantes PP (1961) Mammary cancer induced by a single feeding of polynuclear hydrocarbons and its suppression. Nature 189: 204–207

    Article  PubMed  CAS  Google Scholar 

  6. Jensen EV, Block GF, Smith S, Kyser K, DeSombre ER (1971) Estrogen receptors and breast cancer response to adrenalectomy. Natl Cancer Inst Monogr 34: 55–70

    PubMed  CAS  Google Scholar 

  7. Knight WA, Livingston RB, Gregory EJ, McGuire WL (1977) Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res 37: 4669–4671

    PubMed  CAS  Google Scholar 

  8. Meyer JS, Hixon B (1979) Advanced stage and early relapse of breast adenocarcinoma associated with high thymidine labeling indices. Cancer Res 39: 4042–4047

    PubMed  CAS  Google Scholar 

  9. McGuire WL (1980) Steroid hormone receptors in breast cancer treatment strategy. Recent Prog Horm Res 36: 135–156

    PubMed  CAS  Google Scholar 

  10. McGuire WL, Pearson OH, Segaloff A (1975) Predicting hormone responsiveness in human breast cancer. In: McGuire WL, Carbone PP, Vollmer EP (eds) Estrogen receptors in human breast cancer. Raven, New York, pp 17–30

    Google Scholar 

  11. Nomura Y, Yadagata J, Takenaka K, Tashiro H (1980) Steroid hormone receptors and clinical usefulness in human breast cancer. Cancer 46: 2880–2883

    Article  PubMed  CAS  Google Scholar 

  12. Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG (1977) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II analysis and exemples. Br J Cancer 35: 1–39

    Google Scholar 

  13. Pichón MF, Pallud C, Brunet M, Milgrom E (1980) Relationship of presence of progesterone receptors to prognosis in early breast cancer. Cancer Res 40: 3357–3360

    PubMed  Google Scholar 

  14. Saez S, Chouvet C, Mayer M, Cheix F (1980) Estradiol and progesterone receptor (ER, PGR) as prognostic factors in human primary breast tumors. Proceedings AACR — 553. Cancer Res 21: 139

    Google Scholar 

  15. Saez S, Martin PM, Chouvet CD (1978) Estradiol and progesterone receptor in human breast adenocarcinoma in relation to plasma estrogen and progesterone levels. Cancer 38: 3468–3473

    CAS  Google Scholar 

  16. Skinner LG, Barnes DM, Ribeiro GG (1980) The clinical value of multiple steroid receptor assays in breast cancer management. Cancer 46: 2939–2945

    Article  PubMed  CAS  Google Scholar 

  17. Stoll BA (1969) Hormone management in breast cancer. Pittman Medical, London, pp 68–73

    Google Scholar 

  18. Union Internationale contre le Cancer (1979) Breast. In: UICC (ed) TNM classification of malignant tumors, pp 47–53

    Google Scholar 

  19. Walt AJ, Singhakowinta A, Brooks SC, Cartez A (1976) The surgical implications of estrophile proteins estimations in carcinoma of the breast. Surgery 80: 506–512

    PubMed  CAS  Google Scholar 

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© 1984 Springer-Verlag Berlin · Heidelberg

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Saez, S., Cheix, F., Mayer, M. (1984). Estrogen and Progesterone Receptors as Prognostic Factors in Early Breast Cancer. In: Leclercq, G., Toma, S., Paridaens, R., Heuson, J.C. (eds) Clinical Interest of Steroid Hormone Receptors in Breast Cancer. Recent Results in Cancer Research, vol 91. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82188-2_27

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  • DOI: https://doi.org/10.1007/978-3-642-82188-2_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82190-5

  • Online ISBN: 978-3-642-82188-2

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