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Early Detection of Breast Cancer pp 148–160Cite as

Prognostic Pathologic Factors Among Breast Cancers Detected on Screening by Mammography

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 90))

Abstract

Since screening by both mammography and physical examination have been advocated as means of reducing breast cancer mortality, it is crucial to understand the relative contribution of each modality toward this goal. One means of dealing with this problem is through the use of pathologic parameters related to patient survival. These are lesion size, ratio of infiltrating to intraductal growth, histologic type, histologic grade, extent of tubule formation, lymphatic vessel invasion, and axillary lymph node metastasis. This paper analyzes results of a breast cancer screening project in terms of these pathologic factors. Most cancers classified as minimal or included in other favorable prognostic categories were seen on mammography but were occult to physical examination.

The authors wish to express their appreciation to Arthur S. Patchefsky, M.D., Dept, of Pathology, Jefferson University Hospital, for having reviewed the original histologic slides

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References

  • Adair F, Berg J, Joubert L, Robbins G (1974) Long term followup of breast cancer patients. The 30-year report. Cancer 33:1145–1150

    Article  PubMed  CAS  Google Scholar 

  • Alderson MR, Hamlin I, Staunton MD (1971) The relative significance of prognostic factors in breast carcinoma. Br J Cancer 25:646–656

    Article  PubMed  CAS  Google Scholar 

  • Ashikari R, Huvos AG, Urban JA, Robbins G (1973) Infiltrating lobular carcinoma of the breast. Cancer 31:110–116

    Article  PubMed  CAS  Google Scholar 

  • Ashikari R, Huvos AG, Snyder R (1977) Prospective study of noninfiltrating carcinoma of the breast. Cancer 39:435–439

    Article  PubMed  CAS  Google Scholar 

  • Bloom HJG (1950a) Prognosis in carcinoma of the breast. Br J Cancer 4:259–288

    Article  PubMed  CAS  Google Scholar 

  • Bloom HJG (1950b) Further studies on prognosis of breast carcinoma. Br J Cancer 4:347–367

    Article  PubMed  CAS  Google Scholar 

  • Bloom HJG, Richardson WW (1957) Histological grading and prognosis in breast cancer. Br J Cancer 11:359–374

    Article  PubMed  CAS  Google Scholar 

  • Carstens PHB, Huvos AG, Foote FW Jr, Ashikari R (1972) Tubular carcinoma of the breast. A clinicopathologic study. Am J Clin Pathol 58:231–238

    PubMed  CAS  Google Scholar 

  • Contesso G, Rouesse J, Pettit J-Y, Mouriesse H (1977) Les facteurs anatamopathologiques du prognostic des cancers du sein. Bull Cancer (Paris) 64:525–536

    CAS  Google Scholar 

  • Cutler SJ, Black MM, Torbjorn M, Harvei S, Freeman C (1969) Further observations on prognostic factors in cancer of the female breast. Cancer 24: 653–667

    Article  PubMed  CAS  Google Scholar 

  • Feig SA, Shaber GS, Patchefsky AS, Schwartz GF, Edeiken J, Libshitz HI, Nerlinger R, Curley RF, Wallace JD (1977a) Analysis of clinically occult and mammographically occult breast tumors. AJR 128:403–408

    PubMed  CAS  Google Scholar 

  • Feig SA, Shaber GS, Schwartz GF, Patchefsky A, Libshitz HI, Edeiken J, Nerlinger R, Curley RF, Wallace JD (1977b) Thermography, mammography, and clinical examination in breast cancer screening. Review of 16,000 studies. Radiology 122:123–127

    PubMed  CAS  Google Scholar 

  • Fisher ER, Fisher B (1977) Relationship of pathologic and some clinical discriminants to the spread of breast cancer. Int J Radiat Oncol Biol Phys 2:747–750

    Article  PubMed  CAS  Google Scholar 

  • Fisher B, Slack NH, Bross IDJ (1969) Cancer of the breast. Size of neoplasm and prognosis. Cancer 24:1071–1080

    Article  PubMed  CAS  Google Scholar 

  • Frazier TG, Copeland EM, Gallager HS, Paulus DD, White EC (1977) Prognosis and treatment in minimal breast cancer. Am J Surg 133:697–701

    Article  PubMed  CAS  Google Scholar 

  • Gallager HS, Martin JE (1969a) The study of mammary carcinoma by mammography and whole organ sectioning. Cancer 23:855–873

    Article  PubMed  CAS  Google Scholar 

  • Gallager HS, Martin JE (1969b) Early phases in the development of breast cancer. Cancer 24:1170–1178

    Article  PubMed  CAS  Google Scholar 

  • Gallager HS, Martin JE (1971) An orientation to the concept of minimal breast cancer. Cancer 23:1505–1507

    Article  Google Scholar 

  • Gillis DA, Dockerty MB, Clagett OT (1960) Preinvasive intraductal carcinoma of the breast. Surg Gynecol Obstet 110:555–562

    PubMed  CAS  Google Scholar 

  • Lane N, Husnu G, Salerno RA, Haagensen CD (1961) Clinico-pathologic analysis of the surgical curability of breast cancers. Ann Surg 153:483–498

    Article  PubMed  CAS  Google Scholar 

  • McDivitt RW, Hutter RVP, Foote FW, Stewart FW Jr (1967) In-situ lobular carcinoma. A prospective follow up study indicating cumulative patient risk. JAMA 201:81–86

    Article  Google Scholar 

  • McDivitt RW, Stewart FW, Berg JW (1968) Tumors of the breast. Atlas of tumor pathology, 2nd ser, fasc 2. American Forces Institute of Pathology, Washington, p 86

    Google Scholar 

  • Millis RR, Thynne GSJ (1975) In situ intraductal carcinoma of the breast. A long term follow-up study. Br J Surg 62:957–962

    Article  PubMed  CAS  Google Scholar 

  • Patchefsky AS, Shaber GS, Schwartz GF, Feig SA, Nerlinger R (1977) The pathology of breast cancer detected by mass population screening. Cancer 40:1659–1670

    Article  PubMed  CAS  Google Scholar 

  • Silverberg SG, Chitale AR (1973) Assessment of significance of proportions of intraductal and infiltrating tumor growth in ductal carcinoma of the breast. Cancer 32:830–837

    Article  PubMed  CAS  Google Scholar 

  • Silverberg SG, Chitale AR, Levitt SH (1971) Prognostic significance of tumor margins in mammary carcinoma. Arch Surg 102:450–454

    Article  PubMed  CAS  Google Scholar 

  • Stoll BA (1976) Effect of age on growth pattern. In: Stoll BA (ed) Risk factors in breast cancer. Year Book Medical Publishes, Chicago, pp 129–148 (New aspects of breast cancer vol 2)

    Google Scholar 

  • Tough ICK, Carter EC, Fraser J, Bruce J (1969) Histological grading in breast cancer. Br J Cancer 23:294–301

    Article  PubMed  CAS  Google Scholar 

  • Wallgren A, Silfersward C (1976) Clinical and histological factors of prognostic importance in breast cancer. Int J Radiat Oncol Biol Phys 8:611–617

    Google Scholar 

  • Wallgren A, Silfersward C, Eklund G (1976) Prognostic factors in mammary carcinoma. Acta Radiol (Stockh) 15:1–16

    CAS  Google Scholar 

  • Wanebo HJ, Huvos AG, Urban JA (1974) Treatment of minimal breast cancer. Cancer 33:349–357

    Article  PubMed  CAS  Google Scholar 

  • Young JL Jr, Percy CL, Asire AJ (eds) (1981) Surveillance, epidemiology, and end results: Incidence and mortality data 1973–1977. National Cancer Institute Monograph 57. National Cancer Institute, NIH Publication No. 81–2330

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA, 19107, USA

    S. A. Feig & G. F. Schwartz

Authors
  1. S. A. Feig
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  2. G. F. Schwartz
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Editor information

Editors and Affiliations

  1. Department of Diagnostic Radiology, University of Copenhagen, Gentofte Hospital, 2900, Hellerup/Copenhagen, Denmark

    Sam Brünner MD

  2. Department of Diagnostic Radiology, The County Hospital, University of Århus, 8000, Århus, C., Denmark

    Bent Langfeldt MD

  3. Department of Diagnostic Radiology, University Hospital of Odense, 5000, Odense, C., Denmark

    Paul E. Andersen MD

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© 1984 Springer-Verlag Berlin Heidelberg

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Feig, S.A., Schwartz, G.F. (1984). Prognostic Pathologic Factors Among Breast Cancers Detected on Screening by Mammography. In: Brünner, S., Langfeldt, B., Andersen, P.E. (eds) Early Detection of Breast Cancer. Recent Results in Cancer Research, vol 90. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82031-1_21

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  • DOI: https://doi.org/10.1007/978-3-642-82031-1_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82033-5

  • Online ISBN: 978-3-642-82031-1

  • eBook Packages: Springer Book Archive

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