Abstract
Psychotropic drugs — especially antidepressants and neuroleptics — have become an important element in the treatment of cancer pain. Soon after the introduction of neuroleptics in 1951/52 and antidepressants in 1957 in psychiatry, the first publications appeared reporting their beneficial analgesic effect. Later publications emphasized that psychotropic drugs may potentiate the effects of analgesics and help to reduce their use.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adjan M (1970) Zur therapeutischen Beeinflussung des Schmerzsymptoms bei unheilbaren Tumorkranken. Ther Ggw 109: 1620–1627
Barjou B (1971) Etude du Tofranil sur les douleurs en chirurgie. Revue Med Tours 6: 473–482
Beaumont G (1976) The use of psychotropic drugs in other painful conditions. J Int Med Res [Suppl2] 4: 56–57
Bernard PhA, Scheurer H (1972) Action de la clorimipramine (Anafranil) sur da douleur des cancers en pathologie cervico-faciale. J Fr Otorhinolaryngol 21: 723–729
Bloomfield S, Simard-Savoie S, Bernier J, Tretault L (1964) Comparative analgesic activity of levopromazine and morphine in patients with chronic pain. Can Med Assoc J 90: 1156–1159
Clay GS, Brougham LR (1975) Haloperidol binding to an opiate receptor site. Biochem Pharmacol 42: 1363–1367
Creese J, Feinberg AP, Snyder SH (1976) Butyrophenone influences on opiate receptor. Eur J Pharmacol 36: 231–235
Daxelmüller L (1966) Zur Therapie schwerer Schmerzzustände mit Tofranil. Med Welt 43: 2339–2340
Deutschmann W (1971) Tofranil in der Schmerzbehandlung der Krebskranken. Med Welt 22: 1346–1347
Dilhuydy JM, Miguel Y, Oyon J (1979) Etude en double insu du tiapride dans les algies en carcinologie. Sem Hop Paris 55: 2020–2021
Flohé L, Friderichs E (1978) Alte Probleme und neue Aspekte in der Analgesieforschung. Drug Res 28: 99–106
Gebhart KH, Beller J, Nischk R (1969) Behandlung des Karzinomschmerzes mit Chlorimipramin (Anafranil). Med Klin 64: 751–756
Gennari C, Nami R, Pizzuti M, D’Ascenzo G, Bianchini C (1981) Effects du tiapride en perfusion sur le taux plasmatique de betaendorphine, prolactine et dopamine chez des patients souffrant d’algies cancereuses. Sem Hop Paris 57: 795–800
Gram LF (1974) Influence of neuroleptics and benzodiazepines on metabolism of tricyclic antidepressants in man. Am J Psychiatry 131: 863
Karkalas Y, Lal H (1973) A comparison of haloperidol with methadone in blocking heroin withdrawal symptoms. Int Pharmacopsychiatry 8: 248–251
Kocher R (1969) Zur Behandlung schwerer Schmerzzustände mit einer Kombination von Tofranil (Imipramin) und Nozinan (Laevopromazin). Praxis 57: 1459–1464
Kocher R (1976) The use of psychotropic drugs in the treatment of chronic, severe pains. In: Bonica JJ, Albe-Fessard D (eds) Advances in pain research and therapy, vol 1. Raven, New York, pp 285–289
Kocher R (1979) The use of psychotropic drugs in the treatment of cancer pain. In: Bonica JJ, Ventafridda V (eds) Advances in pain research and therapy, vol 2. Raven, New York, pp 579–582
Lepille D, Bastit Ph (1979) Essai thérapeutique dans les algies néoplasiques. Sem Hop Paris 55: 791–795
Linke H (1963) Die Entpersönlichung des Schmerzes durch Phenothiazinderivate. Ther Berichte 35: 94–99
Maltbie AA, Cavenar O, Sullivan JL, Hammet EB (1979) Analgesia and haloperidol: a hypothesis. J Clin Psychiatry 40: 323–326
Mayer DJ, Price DP (1976) Central nervous system mechanism of analgesia. Pain 2: 379–404
Merskey H, Hester RA (1972) The treatment of chronic pain with psychotropic drugs. Postgrad Med J 48: 494–598
Mönkemeier D, Steffen U (1970) Zur Behandlung mit Imipramin bei Krebserkrankungen. Med Klin 65: 213–215
Pessey JJ, Lacomme Y (1980) Tiapride use in neoplasic algia. Sem Hop Paris 56: 351–353
Put TR (1974) Traitement des douleurs rebelles à l’aide du flupenthixol et du mélitracène. Ars Medici 29: 1401–1413
Simon EJ (1976) The opiate receptors. Neurochem Res 1: 3–28
Spencer PSJ (1976) Some aspects of pharmacology of analgesia. J Int Med Res 4: 1–14
Spencer PSJ, Lee RL, Sewell RDE (1979) Centrally-acting analgesics. A brief review of opiates and psychotropic drugs. Pharmaceut Med 1: 6–20
Takagi H (1980) The nucleus reticularis paragiganto-cellularis as a site of analgesic-action of morphine and enkephalin. Trends Pharmacol Sci 1: 182–184
Taub A, Collins WF (1974) Observations on the treatment on denervation dysaesthesia with psychotropic drugs: postherpetic neuralgia, anaesthesia, dolorosa, peripheral neuropathy. Adv Neurol 4: 309–315
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Kocher, R. (1984). The Use of Psychotropic Drugs in the Treatment of Cancer Pain. In: Zimmermann, M., Drings, P., Wagner, G. (eds) Pain in the Cancer Patient. Recent Results in Cancer Research, vol 89. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82028-1_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-82028-1_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-82030-4
Online ISBN: 978-3-642-82028-1
eBook Packages: Springer Book Archive