Abstract
Up to now the most effective treatment of disseminated liver metastases of colorectal primary has been intra-arterial infusion chemotherapy. The concept of delivering large doses of cytostatics to malignant tumors via vascular isolation was introduced in the 1950s. In an isolated perfusion system, the tumor-bearing liver may be supplied with a high concentration of cytostatics during the perfusion period, while systemic side effects of the drug can be avoided by complete isolation of the perfused area.
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© 1983 Springer-Verlag Berlin · Heidelberg
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Aigner, K. et al. (1983). First Experimental and Clinical Results of Isolated Liver Perfusion with Cytotoxics in Metastases from Colorectal Primary. In: Schwemmle, K., Aigner, K. (eds) Vascular Perfusion in Cancer Therapy. Recent Results in Cancer Research, vol 86. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82025-0_18
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DOI: https://doi.org/10.1007/978-3-642-82025-0_18
Publisher Name: Springer, Berlin, Heidelberg
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