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Genetics of β-Lactam-Producing Actinomycetes

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Antibiotics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 67 / 1))

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Abstract

The commercial usefulness of novel β-lactam antibiotics has turned the interests of the pharmaceutical industry towards the Actinomycetales as a possible source. This group of organisms has provided over the years a rich harvest of new antibiotics, but only recently has it been shown that they are able to produce β-lactam antibiotics (Nagarajan et al. 1971; Nagarajan 1972). This group of substances had been thought to be produced only by fungi up to that point.

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  1. R. Kirby
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  1. Fermentation Microbiology Laboratory, Department of Nutrition and Food Science, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA

    Arnold L. Demain  & Nadine A. Solomon  & 

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Kirby, R. (1983). Genetics of β-Lactam-Producing Actinomycetes. In: Demain, A.L., Solomon, N.A. (eds) Antibiotics. Handbook of Experimental Pharmacology, vol 67 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81966-7_5

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