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Antibiotics pp 301–328Cite as

High-Performance Liquid Chromatography of β-Lactam Antibiotics

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 67 / 1))

Abstract

Analytical procedures for β-lactam antibiotics were described in great detail in the early 1970 s in the monograph Cephalosporins and Penicillins, Chemistry and Biology by Flynn (1972). These procedures included microbiological, chemical, chromatographic, and physical-chemical determinations of this important group of biologically active substances in pharmaceutical preparations, body fluids, and formulations subjected to long-term stability studies.

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Authors
  1. R. D. Miller
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  2. N. Neuss
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Editor information

Editors and Affiliations

  1. Fermentation Microbiology Laboratory, Department of Nutrition and Food Science, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA

    Arnold L. Demain  & Nadine A. Solomon  & 

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© 1983 Springer-Verlag Berlin Heidelberg

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Miller, R.D., Neuss, N. (1983). High-Performance Liquid Chromatography of β-Lactam Antibiotics. In: Demain, A.L., Solomon, N.A. (eds) Antibiotics. Handbook of Experimental Pharmacology, vol 67 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81966-7_10

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  • DOI: https://doi.org/10.1007/978-3-642-81966-7_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81968-1

  • Online ISBN: 978-3-642-81966-7

  • eBook Packages: Springer Book Archive

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