Altered Growth Stimulation and LDL Degradation in Human Arterial Smooth Muscle Cells (ASMC) and Fibroblasts (F) by Low Molecular Weight Serum Factors from Typre II Diabetics
Effects of a prolonged exposure of arterial wall cells to an abnormal metabolic environment have been suspected as angiopathic factors in different metabolic diseases including diabetes. Altered growth and lipoprotein metabolism have been implicated but the nature of the pathogenic metabolic factors in non insulin dependent diabetics (NIDDM) is still unknown.
KeywordsFiltration Recombination Trypsin Cose
- 2).Koschinsky T, Bunting C, Schwippert B, Gries FA (1982) Studies on inherited and acquired metabolic disorders in cultured arterial smooth muscle cells and fibroblasts. Int. J. Obes. (in press)Google Scholar