The Treatment of Hyperlipaemia by Gemfibrozil: A Comparison with Clofibrate

  • A. N. Howard
  • J. Marks
Conference paper


Gemfibrozil is structurally related to Clofibrate and was investigated because of its greater hypotriglyceridaemic activity in the rat. In this species there are some major differences in pharmacological response between the two compounds. In contrast to Clofibrate, gemfibrozil has no effect on total plasma cholesterol or fibrogen, but does increase HDL-cholesterol (l).


Nephrotic Syndrome Carni Tine Cholic Acid Total Plasma Cholesterol Lithogenic Index 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • A. N. Howard
  • J. Marks

There are no affiliations available

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