The Treatment of Hyperlipaemia by Gemfibrozil: A Comparison with Clofibrate
Gemfibrozil is structurally related to Clofibrate and was investigated because of its greater hypotriglyceridaemic activity in the rat. In this species there are some major differences in pharmacological response between the two compounds. In contrast to Clofibrate, gemfibrozil has no effect on total plasma cholesterol or fibrogen, but does increase HDL-cholesterol (l).
KeywordsNephrotic Syndrome Carni Tine Cholic Acid Total Plasma Cholesterol Lithogenic Index
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