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Dietary Prevention of Atherosclerosis in Childhood

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Atherosclerosis VI

Abstract

Despite the enormous body of knowledge that has accumulated on the relationship between nutrition, atherosclerosis and coronary heart disease (CHD), the results of nutritional intervention studies aimed at reducing the incidence of CHD (1,2) have been somewhat disappointing. Although significant reductions in death from CHD have been reported, there has been no significant reduction in total mortality. It is possible that intervention earlier in life would be more effective. Studies in non-human primates have shown that experimentally induced fatty streaks and fibrous plaques can be made to regress by feeding diets low in cholesterol and saturated fat (3). However, only the simplest fatty streaks appear to be truly reversible. It may well be, that two populations of fatty streaks exist: one destined, perhaps by its location or risk factors, to develop into fibrous plaques; and a second which remains as fatty streaks and never goes on to become fibrous plaques (4).

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© 1983 Springer-Verlag Berlin Heidelberg

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Knuiman, J.T., Westenbrink, S., van der Heijden, L., West, C.E., Hautvast, G.A.J. (1983). Dietary Prevention of Atherosclerosis in Childhood. In: Schettler, F.G., Gotto, A.M., Middelhoff, G., Habenicht, A.J.R., Jurutka, K.R. (eds) Atherosclerosis VI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81817-2_10

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  • DOI: https://doi.org/10.1007/978-3-642-81817-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81819-6

  • Online ISBN: 978-3-642-81817-2

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