Liver Cirrhosis

  • C. Isaacson
Conference paper
Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 72)


Higginson et al. (1957) described two major liver lesions in the adult Black of Southern Africa:
  1. 1)

    A diffuse portal fibrosis which, in the more severe cases, was associated with well marked siderosis (micronodular cirrhosis).

  2. 2)

    A “severe” cirrhosis which, in most cases, suggested to these authors a post-necrotic pathogenesis (macronodular). More than half of this group developed hepatocellular carcinoma.



Hepatocellular Carcinoma Iron Overload Prussian Blue Portal Tract Primary Liver Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • C. Isaacson
    • 1
  1. 1.The Laboratory, Baragwanath Hospital, Department of Anatomical Pathology, South African Institute for Medical ResearchUniversity of the WitwatersrandJohannesburgRSA

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