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Osteopathien pp 579-648 | Cite as

Paraneoplastische Osteopathie

  • F. Heuck
Part of the Handbuch der Medizinischen Radiologie Encyclopedia of Medical Radiology book series (HDBRADIOL, volume 5 / 5)

Zusammenfassung

Die erweiterten Kenntnisse über die unspezifischen Fernwirkungen bösartiger Geschwülste auf den Gesamtorganismus haben in den letzten Jahrzehnten zur eingehenden Erforschung der Ursachen und Zusammenhänge geführt. Unabhängig von dem Malignitätsgrad des Primärtumors und seiner Tochtergeschwülste ist eine erstaunliche Vielfalt von begleitenden klinischen Symptomen beschrieben worden, die nicht mit der Art, der Größe und der Lokalisation einer Geschwulst erklärt werden können. Es handelt sich um funktionelle oder organische Störungen, die bei Tumorpatienten beobachtet werden, jedoch keineswegs auf direkte oder lokale Einwirkungen der Geschwulst zurückgeführt werden können. Derartige Symptome oder Befunde können entweder gleichzeitig mit einem Tumor klinisch in Erscheinung treten, einige Zeit vor dem Tumornachweis aber auch erst nach Entdeckung der Geschwulst bemerkt werden. Die Vorstellung, daß ein Zusammenhang zwischen diesen paraneoplastischen Symptomen und dem Tumorleiden bestehen muß, konnte durch Beobachtungen gestützt werden, die eine Rückbildung der Symptome nach operativer Entfernung der Geschwulst oder ein erneutes Auftreten bei einem Tumorrezidiv sowie Tochtergeschwülsten feststellten. Da fundierte Kenntnisse über die Zusammenhänge im einzelnen fehlten, wurden die verschiedenartigsten Symptome unter dem Begriff der „paraneoplastischen Syndrome“ oder der „Paraneoplasie“ zusammengefaßt, obgleich Einzelbeispiele von unspezifischen Fernwirkungen bösartiger Tumoren seit etwa 100 Jahren bekannt und auch mitgeteilt worden sind. So hat Virchow (1855) auf Zusammenhänge zwischen Organverkalkungen bei Hyperkalzämie und Malignomen hingewiesen. Die atypischen Thrombosen bei okkulten Magen- und Pankreas- Karzinomen (Trousseau 1865/77) und die Acanthosis nigricans als kutane Manifestation eines viszeralen Tumors sind in den Lehrbüchern der klinischen Medizin zu finden.

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Literatur

  1. Abelev GI, Assecritova IV, Kraevsky NA (1967) Embryonal serum alpha-globulin in cancer patients; diagnostic value. Int J Cancer 2:551PubMedGoogle Scholar
  2. Adkins D, Martini TJ (1977) Rat osteogenic sarcoma cells. Effects of some prostaglandins, their metabolites and analogues on cyclic AMP production. Prostaglandins 13:861–871Google Scholar
  3. Adler JJ, Sharma OP (1970) Hypertrophic osteoarthropathy with intrathoracic Hodgkin’s disease. Am Rev Respir Dis 102:83–85PubMedGoogle Scholar
  4. Alamartine H (1907) Osteoarthropathies hypertro- phiantes d’origine tuberculeuse. Le role de la tuberculose dans le syndrome de P. Marie. Rev de Chir 35:992–1012Google Scholar
  5. Al-Bahrani ZR, Bakir F (1971) Primary intestinal lymphoma. A challenging problem in abdominal pain. Ann Roy Col Surg 49:103–113Google Scholar
  6. Albrecht HJ (1973) Das Pierre-Marie-Bamberger Syndrom. 53. Tagung der Dtsch Röntgenges 1972. Thieme, Stuttgart, S 56Google Scholar
  7. Albrecht H-J (1972) Lokalisierte paraneoplastische Ostéoarthropathie hypertrophiante pneumonique Pierre Marie-Bamberger. Fortschr Röntgenstr 116:280–281Google Scholar
  8. Albrecht HJ (1972) Stellungnahme zum Diskussionsbeitrag über „Lokalisierte paraneoplastische Osteoarthropathie hypertrophiante pneumonique Pierre-Marie-Bamberger“. Fortschr Röntgenstr 117:359–360Google Scholar
  9. Albrecht H-J, Ellegast HH (1979) Osteoarthropathia hypertrophicans Pierre Marie-Bamberger. In : Schinz Baensch Frommhold Glauner Uehlinger Wellauer (Hrsg) Lehrbuch der Röntgendiagnostik, Bd II/1, 6. Aufl. Thieme, StuttgartGoogle Scholar
  10. Albright F, Burnett CH, Cope O, Parson W (1941) Acute atrophy of bone (osteoporosis) simulating hyperparathyroidism. J Clin Endocrinol 1:711–716Google Scholar
  11. Ali A, Tetalman MR, Fordham EW, Turner DA, Chiles JT, Patel SL, Schmidt KD (1980) Distribution of hypertrophic pulmonary osteoarthropathy. Am J Roentgenol 134:771–780Google Scholar
  12. Allott EN, Skelton MO (1960) Increased adrenocortical activity associated with malignant disease. Lancet I:284–287Google Scholar
  13. Alpert ME, Uriel J, de Nechaud B (1968) Alpha1 feto- globulin in the diagnosis of human hepatoma. N Engl J Med 278:984–992PubMedGoogle Scholar
  14. Ameri MR, Alebouyeh M, Donner MW (1978) Hypertrophic osteoarthropathy in childhood malignancy. Am J Roentgenol 130:992–993Google Scholar
  15. Anderson HA, Bernatz PE (1964) Extrathoracic manifestations of bronchogenic carcinoma. Med Clin North Am 48:921–931Google Scholar
  16. Atkins D, Peacock M (1975) A comparison of the effects of the calcitonin steroid hormones and thyroid hormones on the response of bone to parathyroid hormone in tissue culture. J Endocrinol 64:573PubMedGoogle Scholar
  17. Atkinson MK, McElwain TJ, Peckham MJ, Thomas PRM (1976) Hypertrophic pulmonary osteoarthropathy in Hodgkin’s disease. Reversal with chemotherapy. Cancer 38:1729–1734PubMedGoogle Scholar
  18. Aubry G, Portier H, Tillier F, Cabannes E (1948) Ostéoarthropathie hypertrophiante pneumique de Pierre Marie au cours d’un cancer du poumon. Algérie Méd 51:107PubMedGoogle Scholar
  19. Aufses AH, Aufses BH (1960) Hypertrophic osteoarthropathy in association with pulmonary metastases from extrathoracic malignancies. Dis Chest 38:399–402PubMedGoogle Scholar
  20. Azzopardi JG, Williams ED (1968) Pathology of “ nonendocrine ” tumors associated with Cushing’s syndrome. Cancer 22:274–286PubMedGoogle Scholar
  21. Azzopardi JG, Whittaker RS (1969) Bronchial carcinoma and hypercalcemia. J Clin Pathol 22:718–724PubMedGoogle Scholar
  22. Azzopardi JG, Freeman E, Poole G (1970) Endocrine and metabolic disorders in bronchial carcinoma. Br Med J IV : 528–530Google Scholar
  23. Bach GL (1980) Über die Korrelation rheumatischer Erkrankungen mit Neoplasien. Schwerpunktmed 3:60–63Google Scholar
  24. Ball V, Alamartine H (1912) Tuberculose inflammatoire et ostéoarthropathies hypertrophiantes pneu- moniques. Faz Hop 85:1587–1590Google Scholar
  25. Ball V, Lombard C (1926) Ostéoarthropathy hypertrophiante pneumonique chez les fauvres en captivité. Premier cas de syndrome de Pierre Marie chez une lionne. Bull Acad Méd 95:16–17Google Scholar
  26. Bamberger E (1889) Sitzung der K und K Gesellschaft der Ärzte vom 8. März 1889. Wien Klin Wochenschr 2:226Google Scholar
  27. Bamberger E (1889) Vorstellung von 2 Fällen mit hypertrophischer Osteoarthropatie. Wien Klin Wochenschr 2:226–227Google Scholar
  28. Bamberger E (1890) Über Knochenveränderungen bei chronischen Lungen- und Herzkrankheiten. Z Klin Med 18:193–217Google Scholar
  29. Barclay N, Ogbeide M, Grillo IA (1970) Gross hypertrophic pulmonary osteoarthropathy in a 7 year old child. Thorax 25:484–489PubMedGoogle Scholar
  30. Barden RP (1967) Para-endocrine syndromes associated with carcinoma of the lung. Am J Roentgenol 100:626–630Google Scholar
  31. Bariéty M, Coury C (1950) L’ostéoarthropathie hypertrophiante pneumique et les dysacromélies d’origine thoracique. Aspects anatomo-cliniques et évolutifs (à propos de 25 cas). Sem Hop Paris 26:1681PubMedGoogle Scholar
  32. Bariéty M, Coury C (1950) Essai sur les rapports et la pathogénie de l’hippocratisme digital et de l’os- téoarthropathie hypertrophiante pneumique (dysacromélies d’origine thoracique). Sem Hop Paris 26:1709PubMedGoogle Scholar
  33. Bariéty M, Coury C, Rullière R (1964) Les syndromes paranéplastiques dans le cancer broncho-pulmonaire primitif. J Fr Med Chir Thor 18:19–68Google Scholar
  34. Barzel US (1972) The differential diagnosis of hypercalcemia. Ann Intern Med 76:825–826PubMedGoogle Scholar
  35. Bazex A, Salvador R, Dupré A, Parant M, Christol B, Cantala P, Cariés P (1967) Dermatose psoriasiforme acromélique d’étiologie cancéreus (Entité para-néoplasique originale) Bull Soc Franc Derm Symph 74:130–135Google Scholar
  36. Becher E (1917) Ein Fall von Osteoarthropathie hypertrophiante (Marie) ohne primäre Erkrankung. Z Klin Med 94:491–498Google Scholar
  37. Beck C, Burger HG (1972) Evidence for the presence of immunoreactive growth hormone in cancers of the lung and stomach. Cancer 30:75PubMedGoogle Scholar
  38. Becker (1917) zitiert nach Hoffmann V. Z Klin Med 94:491Google Scholar
  39. Becker LL, Cottrell J, Moore ChF, Winnacker JL, Mathews MJ, Katz S (1968) Endocrine studies in a patient with a gonadotropin-secreting bronchogenic carcinoma. J Clin Endocrinol Metab 28:809PubMedGoogle Scholar
  40. Becker V (1971) Pathologisch-anatomische Aspekte bei endokrin wirksamen Tumoren. Langenbecks Arch Chir 329:426PubMedGoogle Scholar
  41. Bedacht R, Metzner U, Mohr U, Speisberg F, Wilhelm M (1973) Diagnose, Differentialdiagnose und Therapie der tumorähnlichen Knochenerkrankungen. Hippokrates 44:49–63PubMedGoogle Scholar
  42. Beighton P (1968) LATS-activity, exophthalmus and digital clubbing associated with myxoedema. Postgrad Med J 44:426PubMedGoogle Scholar
  43. Beliel OM, Singer FR, Coburn JW (1973) Prostaglandins: Effect on plasma calcium concentration. Prostaglandins 3:237–241PubMedGoogle Scholar
  44. Bender RA, Hansen H (1974) Hypercalcemia in bronchogenic carcinoma: A prospective study of 200 patients. Ann Intern Med 80:205–208PubMedGoogle Scholar
  45. Bennett A, McDonald AM, Simpson JS, McDonald AM, Stamford IF (1975) Breast cancer, prostaglandins, and bone metastases. Lancet 1:1218–1220PubMedGoogle Scholar
  46. Bennett A, Charlier EM, McDonald AM, Simpson JS, Stamford IF (1976) Bone destruction by breast tumours. Prostaglandins 11:461–463PubMedGoogle Scholar
  47. Bennett A, Charlier WM, McDonald AM, Simpson JS, Stamford IF, Zebro T (1977) Prostaglandins and breast cancer. Lancet II : 624Google Scholar
  48. Benson RC, Riggs BL, Pickard BM, Arnaud CD (1974) Radioimmunoassay of parathyroid hormone in hypercalcemic patients with malignant disease. Am J Med 56:821PubMedGoogle Scholar
  49. Benvestini D, Goldberg H (1975) Prostaglandins, indo- methacin and hypercalcemia in neoplastic disease. N Engl J Med 292:1189Google Scholar
  50. Berk M (1952) Chronic idiopathic hypertrophic osteoarthropathy. N Engl J Med 247:123–126PubMedGoogle Scholar
  51. Berman B (1963) Pulmonary hypertrophic osteoarthropathy. Arch Intern Med 112:947–953PubMedGoogle Scholar
  52. Berson SA, Yalow RS (1966) Parathyroid hormone in plasma in adenomatous hyperparathyroidism, uremia and bronchogenic carcinoma. Science 154:907–909PubMedGoogle Scholar
  53. Berthelot P, Benhamou JP, Fauvert R (1961) Hypercorticisme et cancer de’l utérus. Presse Méd 69:1899PubMedGoogle Scholar
  54. Bessler W (1969) Veränderter Mineralgehalt des Knochens im Röntgenbild und Szintigram. Radiologe 9:154PubMedGoogle Scholar
  55. Bieler E, Albrecht H-J (1971) Das szintigraphische Bild der Ostéoarthropathie hypertrophiante. Nucl Med 10:196–200Google Scholar
  56. Billinghurst JR, Thould AK, Galpim OP, Hinton JM (1961) Carcinoma and Cushing’s syndrome. Br J Med II:490Google Scholar
  57. Bloom W (1948) Pituitary implications in hypertrophic pulmonary osteoarthropathy. Ann Intern Med 29:361–370PubMedGoogle Scholar
  58. Bockman RS, Myers WPL, Kempin S, Bajorunas D (1977) Prostaglandin E in cancer patients. Clin Res 25:387 A (abstract)Google Scholar
  59. Bonakdarpour A, Levy W, Aergerter E (1971) Osteosclerotic changes in sarcoidosis. Am J Roentgenol 113:646–649Google Scholar
  60. Bornstein P, Nolan JP, Bernanle D (1961) Adrenocortical hyperfunction in association with anaplastic carcinoma of the respiratory tract. N Engl Med J 264:363Google Scholar
  61. Brower AC, Teates CD (1974) Positive 99m-Tc-Poly- phosphate scan in case of metastatic osteogenic sarcoma and hypertrophic pulmonary osteoarthropathy. J Nucl Med 15:53–55PubMedGoogle Scholar
  62. Brown WH (1928) A case of pluriglandular syndrome: Diabetes of bearded woman. Lancet II: 1022Google Scholar
  63. Brunner A (1936) Chirurgie der Lungen und Pleura. Helv Med Acta 3:766–797Google Scholar
  64. Brunner W (1967) „Subakute Polyarthritis“ bei Bron- chial-Karzinom - ein paraneoplastisches Syndrom. Schweiz Med Wochenschr 97:611PubMedGoogle Scholar
  65. Bryan L (1925) Secondary hypertrophic osteoarthropathy following metastatic sarcoma of the lung. California & West Med 23:449Google Scholar
  66. Buchan DJ, Mitchell DM (1967) Hypertrophic osteoarthropathy in portal cirrhosis. Ann Intern Med 66:130–135PubMedGoogle Scholar
  67. Buchman D, Hrowat EA (1956) Idiopathic clubbing and hypertrophic osteoarthropathy. Arch intern Med 95:355–358Google Scholar
  68. Bürki K, Cottier P, Bandi W, Antener I (1963) Bestimmung der Vitamin-D-Aktivität bei Hypernephrom mit Hypercalcämiesyndrom. Helv Med Acta 30:615–627PubMedGoogle Scholar
  69. Burkhardt L (1959) „Paget“-ähnliche Strukturbilder bei der pneumonischen Osteopathie. Verh Dtsch Ges Pathol 42:185–188, Fischer, StuttgartGoogle Scholar
  70. Cabot RC, Castelman B, Kibbee BU (1958) Case records of the Massachusetts General Hospital - Case 44 491. N Engl J Med 259:1128–1134Google Scholar
  71. Cantrell EG (1969) Nephrotic syndrome cured by removal of gastric carcinoma. Brit Med J 1:739–740Google Scholar
  72. Capen CC, Koestner A, Cole CR (1965) The ultrastructure, histopathology, and histochemistry of the parathyroid glands of pregnant and nonpregnant cows fed a high level of Vitamin D. Lab Invest 14:1809–1825PubMedGoogle Scholar
  73. Carey RM, Orth DN, Hartman WH (1973) Malignant melanoma with ectopic production of ACTH ; palliative treatment with inhibitors of adrenal steroid biosynthesis. J Clin Endocrinol Metab 36:482PubMedGoogle Scholar
  74. Carey VCI (1966) The incidence of hypercalcemia in association with bronchogenic carcinoma. Am Rev Respir Dis 93:584–586PubMedGoogle Scholar
  75. Carlson WD, Gilette EL (1967) Secondary hypertrophic pulmonary osteoarthropathy. In: Veterinary Radiology 2nd Ed. Lea & Febiger, PhiladelphiaGoogle Scholar
  76. Case 31 281 (1945) Case Records of the Massachusetts General Hospital. N Engl J Med 233:44–47Google Scholar
  77. Case (63–1964) (1964) Case Records of the Massachusetts General Hospital. N Engl J Med 270:898–906Google Scholar
  78. Castex MR, Mazzei ES, Schaposnik F (1950) Pachydermia plicata mit hypertrophischer Pachyperiostose (Pachyperiostiodermie). Ihr Auftreten bei broncho-pulmonalen Karzinomen. Schweiz Med Wochenschr 80:25–28PubMedGoogle Scholar
  79. Castleman B (1963) Weekly clinicopathological exercises Case 29–1963. N Engl J Med 268:943–950Google Scholar
  80. Castleman B, Knowles W (1957) Case presentation (73–1961). N Engl J Med 256:145–751Google Scholar
  81. Castleman B, McNeely BU (1964) Weekly clinicopathological exercises Case 21–1964. N Engl J Med 270:898–906Google Scholar
  82. Cavanaugh JJA, Holman GH (1965) Hypertrophic osteo-arthropathy in childhood. J Pediatr 66:27–40PubMedGoogle Scholar
  83. Chamberlain MJ, Shortland-Webb WR (1975) Osteomalacia and carcinoma of prostate with major redistribution of skeletal calcium. Br J Radiol 48:451–456PubMedGoogle Scholar
  84. Charr R, Swenson PC (1946) Clubbing fingers. Am J Roentgenol 55:325–330Google Scholar
  85. Chase LR (1975) Selective proteolysis of the receptor for parathyroid hormone in renal cortex. Endocrinology 96:70–76PubMedGoogle Scholar
  86. Chase LR, Aurbach GD (1970) The effect of parathyroid hormone on the concentration of adenosine 3´, 5´-monophosphate in skeletal tissue in vitro. J Biol Chem 245:1520–1526PubMedGoogle Scholar
  87. Chase LR, Obert KA (1975) Selective proteolysis of the receptor for parathyroid hormone in skeletal tissue. Metabolism 24:1067–1071PubMedGoogle Scholar
  88. Chaudhuri TK, Shapiro RL, Christie JH (1972) Positive 87m Sr bone scan in a case of hypertrophic pulmonary osteoarthropathy. J Nucl Med 13:120–121PubMedGoogle Scholar
  89. Christy NP (1961) Adrenocorticotrophic activity in plasma of patients with Cushing’s syndrome associated with pulmonary neoplasms. Lancet 1:85PubMedGoogle Scholar
  90. Cohen JD, Utiger RD (1970) Metastatic choriocarcinoma associated with hyperthyroidism. J Clin Endocrinol Metab 30:423PubMedGoogle Scholar
  91. Compere EL, Adams WE, Compere CL (1931) Possible etiologic factors in the production of pulmonary osteoarthropathy. Proc Soc Exper Biol Med 28:1083–1084Google Scholar
  92. Coombes RC, Easty GC, Detre SI, Hillyard CJ, Stevens U, Girgis SI, Galante LS, Heywood L, MacIntyre I, Neville AM (1975) Secretion of im- munoreactive calcitonin by human breast carcinomas. Br Med J IV: 197Google Scholar
  93. Corrin B, Gilby ED, Jones NF, Patrick J (1973) Oat cell carcinoma of the pancreas with ectopic ACTH secretion. Cancer 31:1523PubMedGoogle Scholar
  94. Coury C (1960) Hippocratic fingers and hypertrophic osteoarthropathy: a study of 350 cases. Brit J Dis Chest 54:202–209PubMedGoogle Scholar
  95. Cox ML, Gourley RD, Kitabchi AE (1970) Acinic cell adenocarcinoma of the parotid with ectopic production of adenocorticotropic hormone. Am J Med 49:529PubMedGoogle Scholar
  96. Cragg J (1971) Endocrine and metabolic disorders in bronchial carcinoma. Br Med J 2:110–111PubMedGoogle Scholar
  97. Craig JW (1937) Hypertrophic pulmonary osteo-ar- thropathy as the first symptom of pulmonary neoplasm. Br Med J 1:750–752PubMedGoogle Scholar
  98. Croft PB, Wilkinson M (1965) The incidence of carcinomatous neuropathy in patients with various types of carcinoma. Brain 88:427–434PubMedGoogle Scholar
  99. Crooke AC (1946) Basophilism and carcinoma of the pancreas. J Pathol Bact 58:667–673Google Scholar
  100. Crump C (1929) Histologie der allgemeinen Osteophytose (Ostéoarthropathie hypertrophiante pneumique). Virchows Arch [Pathol Anat] 271:467–511Google Scholar
  101. Cudkowicz L, Wraith D (1957) Evaluation of clinical significance of clubbing in common lung disorders. Br JTuberc 51:14–31Google Scholar
  102. Cullen DR, Maskery PJ (1966) Clubbing of the fingers and hypertrophic osteoarthropathy in pregnancy. Lancet 1:473Google Scholar
  103. Cummings KB, Wheelis RF, Robertson RP (1975) Prostaglandin: increased production by renal cell carcinoma. Surg Forum 26:572–574PubMedGoogle Scholar
  104. Dailey JE, Marcuse PM (1969) Gonadotropin secreting giant cell carcinoma of the lung. Cancer 24:388PubMedGoogle Scholar
  105. Danowski TS (1976) Outline of Endocrine Gland Syndromes. Williams & Wilkins, BaltimoreGoogle Scholar
  106. Danuco I, Graure StE, Benetato G (1931) Betrachtungen und Beiträge zur Osteoarthropathia hypertro- phicans (Pierre Mariesche Krankheit) in Verbindung mit einem klinischen Fall. Zentralbl Radiol 10:735Google Scholar
  107. Daughtry DC, Chesney JG, Spear HC (1967) Unexplained systemic manifestations of malignant lung tumors. Dis Chest 52:632–639PubMedGoogle Scholar
  108. Davis RB, Kennedy BJ (1962) Carcinoid syndrome associated with adrenal hyperplasia. Arch intern Med 109:192–200PubMedGoogle Scholar
  109. Day EA, Malcom AT, Beeler MF (1969) Tumor sterols. Metabolism 18:646–651PubMedGoogle Scholar
  110. De Gennes L, Bricaire H, Leprat J (1962) Paraneoplastic endocrine syndromes (Abstract). Presse Méd 70:2035PubMedGoogle Scholar
  111. De Gennes L, Bricaire H, Leprat J (1962) Les syndromes endocriniens paranéoplasiques. Presse Méd 70:2137PubMedGoogle Scholar
  112. Demers LM, Allegra JC, Harvey HA, Lipton A, Luderer JR, Mortel R, Brenner DE (1977) Plasma prostaglandins in hypercalcemic patients with neoplastic disease. Cancer 39:1559–1562PubMedGoogle Scholar
  113. Denck H, Titscher R (1973) Pseudohyperparathyreoidismus. In: Mlczoch und Seidel (Hrsg) Aktuelle Fragen der Lungenpathologie. Thieme, StuttgartGoogle Scholar
  114. Dent CE (1962) Some problems of hyperparathyroidism. Br Med J 11:1419–1425Google Scholar
  115. Dent CE (1976) Metabolic forms of rickets (and osteomalacia) In: Bickel, Stern (ed) Inborn Errors of Calcium and Bone Metabolism. Garden City Press, LetchworthGoogle Scholar
  116. Dent CE, Friedman M (1964) Hypophosphatemic osteomalacia with complete recovery. Br Med J 1:1676–1679PubMedGoogle Scholar
  117. D’Eshougues JR (1963) Les lésions périostées de la maladie de Pièrre Marie. Ostéoarthropathie hypertrophiante „Pneumonique„. Atlas de Radiol Clin (Paris) Presse Méd 71:1–4Google Scholar
  118. Deutschberger O, Maglin AA, Gill JJ (1953) An unusual case of intrathoracic fibroma associated with pulmonary hypertrophic osteoarthropathy. Am J Roentgenol 69:738–744Google Scholar
  119. Dietrich JW, Goodson JM, Raisz LG (1975) Stimulation of bone resorption by various prostaglandins in organ culture. Prostaglandins 10:231–240PubMedGoogle Scholar
  120. Dietrich JW, Raisz LG (1975) Prostaglandin in calcium and bone metabolism. Clin Orthop 111:228–237PubMedGoogle Scholar
  121. Dietrich JW, Canalis EM, Maina DM, Raisz GL (1976) Hormonal control of bone collagen synthesis in vitro. Effects of parathyroid hormone and calcitonin. Endocrinology 98:943–949PubMedGoogle Scholar
  122. Dihlmann W, Frik W (1973) Die tumorinduzierte un- spezifische Kompaktareaktion. Fortschr Röntgenstr 119:64–74Google Scholar
  123. Diner WC (1962) Hypertrophic osteoarthropathy: relief of symptoms by vagotomy in patient with pulmonary metastases from lympho-epithelioma of nasopharynx. JAMA 181:555–557PubMedGoogle Scholar
  124. Dor L (1892) Sur une ostéo-arthrite hypertrophique infectieuse produite expérimentalement chez le lapin. Lyon Méd 69:538–542Google Scholar
  125. Dowsett M, Eastman AR, Easty DM, Easty GC, Powles TJ, Neville AM (1976) Prostaglandin mediation of collagenase-induced bone resorption. Nature 263:72–74PubMedGoogle Scholar
  126. Dowsett M, Easty DM, Easty CG, Neville AM (1976) Breast cancer osteolysis, bone metastases, and anti- osteolytic effect of aspirin. Lancet 1:608PubMedGoogle Scholar
  127. Dowsett M, Easty GC, Powles TJ, Easty DM, Neville AM (1976) Human breast tumor-induced osteolysis and prostaglandins. Prostaglandins 11:447–463PubMedGoogle Scholar
  128. Dowzenko A, Staniszewska J (1973) Hypertrophic osteoarthropathy - Osteoartropatia przerostowa Pol Przegl Radiol 37:709–712PubMedGoogle Scholar
  129. Drezner MK, Feinglos MN (1977) Osteomalacia due to Iα-25-dihydroxychole-calciferol deficiency. Association with a giant cell tumor of the bone. J Clin Invest 60:1046–1053PubMedGoogle Scholar
  130. Dube WJ, Bell GD, Aliapoulios MA (1969) Thyrocalcitonin activity in metastatic medullary thyroid carcinoma. Arch Intern Med 123:423PubMedGoogle Scholar
  131. Eckelman WC, Reba RC, Kubota H, Stevenson JS (1974) 99m Tc-pyrophosphate for bone imaging. J Nucl Med 15:279–283PubMedGoogle Scholar
  132. Edeiken J, Hodes PJ, Caplan LH (1966) New bone production and periosteal reaction. Am J Roentgenol 97:708–718Google Scholar
  133. Edeiken J, Hodes PhJ (1973) Roentgen diagnosis of diseases of bone, 2. edn. Williams & Wilkins, BaltimoreGoogle Scholar
  134. Epstein O, Ajdukiewicz AB, Dick R, Sherlock Sh (1979) Hypertrophic hepatic osteoarthopathy. Am J Med 67:88–97PubMedGoogle Scholar
  135. Evans DJ, Azzopardi JG (1972) Distinctive tumors of bone and soft tissue causing acquired vitamin-D- resistant. Osteomalacia. Lancet I:353–354Google Scholar
  136. Evertz W, Pfeiffer EF (1970) Cushing’s syndrome following ectopic neoplastic production of corticotropin. Horm Metab Res 2:213PubMedGoogle Scholar
  137. Faiman C, Colwell JA, Ryan RJ (1967) Gonadotropin secretion from a bronchogenic carcinoma ; demonstration by radioimmunotherapy. N Engl J Med 277:1395PubMedGoogle Scholar
  138. Feyrter F, Unna K (1937) Über den Nachweis eines blutdrucksteigernden Stoffes im Carcinoid. Virchows Arch pathol Anatomie, Physiol u Klin Med 298:187Google Scholar
  139. Firooznia H, Seliger G, Genieser NB, Barasch E (1975) Hypertrophic pulmonary osteoarthropathy in pulmonary metastases. Radiology 114:269–274Google Scholar
  140. Fischer DS, Singer DH, Feldman SM (1964) Clubbing: review with emphasis on hereditary acropachy. Medicine 43:459–479PubMedGoogle Scholar
  141. Fischer E (1979) Die Weichteilveränderungen der Finger bei der rheumatischen Polyarthritis. Er gebnisse nach Weichteilaufnahmen in drei Ebenen. Radiologe 19:119–137PubMedGoogle Scholar
  142. Fischer E, Manolakis P (1967) Das röntgenologische Frühzeichen der rheumatischen Polyarthritis nach Norgaard bei der Osteopathia hypertrophicans toxica. Fortschr Röntgenstr 106:844–847Google Scholar
  143. Fischl JR (1950) Severe hypertrophic pulmonary osteoarthropathy. Am J Roentgenol 64:42–46Google Scholar
  144. Fisher JA, Blum JW, Binswanger U (1973) Epinephrine and the regulation of parathyroid hormone and calcitonin secretions in vivo. Clin Res 21:623Google Scholar
  145. Flavel G (1956) Reversal of pulmonary hypertrophic osteoarthropathy by vagotomy. Lancet 1:260–262Google Scholar
  146. Fornasier VL, Czitrom AA (1978) Collapsed vertebrae: a review of 659 autopsies Clin. Orthop 131:261–265Google Scholar
  147. Forschbach G (1973) Ostéoarthropathie hypertrophiante pneumique - eine Paraneoplasie. In : Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Herausgeb: Thieme, StuttgartGoogle Scholar
  148. Forschbach G, Hoffmann K (1952) Über ein seltenes Frühsymptom intrathorakaler Tumoren (Beitrag zur Ostéoarthropathie hypertrophante pneumonique Pierre-Marie-Bamberger). Münch Med Wochenschr 94:1271–1274PubMedGoogle Scholar
  149. Forssell J (1958) Nephrogenous polycythaemia. Acta Med Scand 161:169–179PubMedGoogle Scholar
  150. Fränkel E (1918) Über allgemeine Periostitis hyper- plastica. Fortschr Röntgenstr 25:401Google Scholar
  151. Freeman MH, Tonkin AK (1976) Manifestations of hypertrophic pulmonary osteoarthropathy in patients with carcinoma of the lung. Demonstration by 99m Tc-pyrophosphate bone scans. Radiology 120:363–365PubMedGoogle Scholar
  152. Freytag AFC (1891) Über die Trommelschlägelfinger und Knochenveränderungen bei chronischen Lungen- und Herzkrankheiten. Diss Univ BonnGoogle Scholar
  153. Fried BM (1943) Chronic pulmonary osteoarthropathy. Arch Intern Med 72:565–580Google Scholar
  154. Friedman M, Mar shall-Jones P, Ross EJ (1966) Cushing’s syndrome: Adrenocortical hyperactivity secondary to neoplasms arising outside the pituitary- adrenal system. Q J Med 35:193PubMedGoogle Scholar
  155. Fritze D, Fritze M, Kaufmann M, Drings P (1978) Immundiagnostische Aspekte beim Mammakarzinom. Dtsch Med Wochenschr 103:306–308PubMedGoogle Scholar
  156. Fry L (1962) Pseudohyperparathyroidism with carcinoma of bronchus. Br Med J 1:301–302PubMedGoogle Scholar
  157. Fusco FD, Rosen SW (1966) Gonadotropin-producing anaplastic large-cell carcinomas of the lung. N Engl J Med 275:507–515PubMedGoogle Scholar
  158. Galasko CSB (1976) Mechanism of bone destruction in the development of skeletal metastases. Nature 263:507–508PubMedGoogle Scholar
  159. Galasko CBS, Bennett A (1976) Relationship of bone destruction in skeletal metastases to osteoclast activation and prostaglandins. Nature 263:508–510PubMedGoogle Scholar
  160. Gall EA, Bennett GA, Bauer W (1951) Generalized hypertrophic osteoarthropathy. Am J Pathol 27:349–381PubMedGoogle Scholar
  161. Ganzoni A (1964) Hypercalcämiesyndrom. Schweiz Med Wochenschr 94:855–861PubMedGoogle Scholar
  162. Gardner B (1969) The relation between serum calcium and tumor metastases. Surg Gynecol Obstet 128:369–374PubMedGoogle Scholar
  163. Gast LF (1965) Pulmonale Osteoarthropathie ; juvenile Form und unvollständige Formen. J belge Rhum Méd Phys 20:215–224Google Scholar
  164. CRIGault MH, Kinsella TD (1965) Carcinoma of lung with adrenal hyperfunction and hypercalcemia treated by parathyroidectomy. Can Med Assoc J 92:317–324PubMedGoogle Scholar
  165. Gault MH, Bilefsky R, Kinsella TD, Aronoff A (1965) Adrenocortical hyperfunction associated with bronchogenic carcinoma. Can Med Assoc J 93:1243–1249PubMedGoogle Scholar
  166. Gehrig D, Kaulbach W (1958) Zur Ostéoarthropathie hypertrophiante pneumonique (Bamberger-Marie) als Frühsymptom des Bronchialcarcinoms. Ärztl Wochenschr 13:756–759Google Scholar
  167. Genant HK, Boyd D (1977) Quantitative bone mineral analysis using dual computerized tomography. Invest Radiol 12:545–551PubMedGoogle Scholar
  168. Gertner HR, Wilson JR, Woodward ER (1964) Parathormone bioassay of plasma in hypercalcemic tumor rabbits. Proc Soc Exp Biol Med 116:177–178PubMedGoogle Scholar
  169. Gewirtz G, Yalow RS (1974) ACTH production in carcinoma of the lung. J Clin Invest 53:1022PubMedGoogle Scholar
  170. Ghosh L, Muehrcke RC (1970) The nephrotic syndrome: A prodrome to lymphoma. Ann Intern Med 72:379–382PubMedGoogle Scholar
  171. Gibbs DD, Schiller KFR, Stovin PGI (1960) Lung metastases heralded by hypertrophic pulmonary osteoarthropathy. Lancet 1:623–625PubMedGoogle Scholar
  172. Gilmore WM, Black LT (1949) zitiert nach: Thompson I. Clubbing of the fingers. Arch Pediat 66:216–232Google Scholar
  173. Ginsburg J (1958) Observations on peripheral circulation in hypertrophic pulmonary osteoarthropathy. Q J Med 27:335–352PubMedGoogle Scholar
  174. Ginsburg J, Brown JB (1961) Increased oestrogen excretion in hypertrophic pulmonary osteoarthropathy. Lancet 11:1274–1276Google Scholar
  175. Gold P (1967) Circulating antibodies against carcino- embryonic antigens of human colonic tumours. Cancer Res 20:1663Google Scholar
  176. Goldberg MF, Tashjian AH, Order SE, Dammin GJ (1964) Renal adenocarcinoma containing a parathyroid hormone-like substance and associated with marked hypercalcemia. Am J Med 36:805–814PubMedGoogle Scholar
  177. Golde DW, Schambelan M, Weintraub BD, Rosen SW (1974) Gonadotropin secreting renal carcinoma. Cancer 33:1048PubMedGoogle Scholar
  178. Goldhaber P, Rabadjja L, Beyer WR, Kornhauser A (1973) Bone resorption in tissue culture and its relevance to peridontal disease. J Am Dent Assoc 87:1027–1033PubMedGoogle Scholar
  179. Gordan GS (1967) Hormonal effects on nonendocrine tumors with special reference to the hypercalcemia of breast cancer. In: Segaloff, Meyer, DeBakey (eds) Current Concepts in Breast Cancer. Williams & Wilkins, BaltimoreGoogle Scholar
  180. Gordan GS (1974) Hyper- and hypocalcemia: Pathogenesis and treatments. Ann NY Acad Sci 230:181–186PubMedGoogle Scholar
  181. Gordan GS, Cantino TJ, Erhardt L, Hansen J, Lubich W (1966) Osteolytic sterol in human breast cancer. Science 151:1226–1228Google Scholar
  182. Gorman JT, Schnider BI, O’Conner T (1958) Hypertrophic osteoarthropathy: report of a case associated with lymphosarcoma. Med Ann DC 27:242PubMedGoogle Scholar
  183. Grafe E, Schneider P (1913) Zur Kenntnis der sekundären hyperplastisch-porotischen Osteoperiostitis. Beitr Pathol Anatomie und Allgem Pathol 56:23Google Scholar
  184. Greenberg PB, Beck C, Martin TJ, Burger HG (1972) Synthesis and release of human growth hormone from lung carcinoma in cell culture. Lancet 1:350PubMedGoogle Scholar
  185. Greenfield GB, Escamilla CH, Schorsch HA (1967) Hand as an indicator of generalized disease. Am J Roentgenol 99:736–745Google Scholar
  186. Greenfield GB, Schorsch HA, Shkolnik A (1967) The various Roentgen appearances of pulmonary hypertrophic osteoarthropathy. Am J Roentgenol 101:927–931Google Scholar
  187. Greven J (1979) Prostaglandine. Biochemische Grundlagen und physiologische Bedeutung. Med Klin 74:591PubMedGoogle Scholar
  188. Greven J (1979) Prostaglandine. Wirkungen auf einzelne Organsysteme und klinische Bedeutung. Med Klin 74:597PubMedGoogle Scholar
  189. Gros M, Voegtlin, Frühling, Speeg (1950) Contribution a l’étude de la périostose engainante. J Radiol Electrol Nucl 31:153–159Google Scholar
  190. Grossman H, Denning CR, Baker DH (1964) Hypertrophie osteoarthropathy in cystic fibrosis. Am J Dis Child 107:1–6PubMedGoogle Scholar
  191. Grunberg A (1936) Zur Genese der Trommelschlegelfinger Klin Wochenschr 15:471Google Scholar
  192. Gutman AB, Tyson TL, Gutman EB (1936) Serum calcium, inorganic phosphorus and phosphotase activity in hyperparathyroidism, Paget’s disease, multiple myeloma, and neoplastic disease of the bones. Arch Intern Med 58:379–413Google Scholar
  193. Guye GA (1917) Notes sur un cas d’ostéoarthropathie hypertrophiante pneumique de Pierre Marie. Rev Med Suisse Romande 37:760Google Scholar
  194. Haas HG (1967) Paraneoplastisches Cushing-Syndrom bei ektopischer ACTH-Bildung. Schweiz Med Wochenschr 97:88–89PubMedGoogle Scholar
  195. Hagedorn M, Häuf GF, Thomas C (1978) Paraneoplasien, Tumor Syntropien und Tumor syndrome der Haut. Springer, Wien New YorkGoogle Scholar
  196. Hall ThC (1968) Symptomatic hypercalcemic alcalosis in hyperadenocorticism secundary to carcinoma of the prostate. Cancer 21:190PubMedGoogle Scholar
  197. Hall ThC (Editor) (1974) Paraneoplastic Syndromes. Ann NY Acad Sci 230Google Scholar
  198. Hall ThC (1974) Oncocognitive autoimmunity and other paraneoplastic syndromes yet to be described. Ann NY Acad Sci 230:565–577PubMedGoogle Scholar
  199. Hamberg M (1974) Quantitative studies on prostaglandin synthesis in man. III. Excretion of the major urinary metabolite of prostaglandins F and F during pregnancy. Life Sciences 14:247–252PubMedGoogle Scholar
  200. Hamberg M, Samuelsson B (1972) On the metabolism of prostaglandin E1 and E2 in man. J Biol Chem 247:3495–3502PubMedGoogle Scholar
  201. Hamberg M, Svensson J, Samuelsson B (1975) Thromboxanes : A new group of biologically active compounds derived from prostaglandin endoperoxydes. Proc Nat Acad Sci USA 72:2994–2998PubMedGoogle Scholar
  202. Hammarsten JF, O’Leary J (1957) The features and significance of hypertrophic osteoarthropathy. Arch Intern Med 99:431–441Google Scholar
  203. Hammerström S, Samuelsson B, Bjursell G (1973) Prostaglandin levels in normal and transformed baby- hamster kidney fibroblasts. Nature (New Biol) 243:50Google Scholar
  204. Han SY, Collins LC (1968) Hypertrophic osteoarthropathy in cirrhosis of the liver. Radiology 91:795–797Google Scholar
  205. Hancok BW, Richmond J, Powell T, Emmanuel IG (1976) Intrathoracic Hodgkin’s disease presenting as hypertrophic osteoarthropathy. Br J Radiol 49:647–649Google Scholar
  206. Hansen JL (1952) Bronchial carcinoma presenting as arthralgia. Acta Med Scand [Suppl 266] 142:467–472Google Scholar
  207. Harper FR, Patterson LT (1955) Osteoarthropathy in carcinoma of the lung. Arch Surg 70:643–646Google Scholar
  208. Hartman GR, Meek J (1972) Acromegaly and bronchial carcinoid tumor. Clin Res 20:776Google Scholar
  209. Hartmann F, Lehmann H (1973) Hyperkalzämiesyndrom bei Sarkoidose der Epithelkörperchen. Med Klin 68:1365–1370PubMedGoogle Scholar
  210. Hathaway BM, Copeland K, Gurley J (1969) Giant cell adeno-carcinoma of the lung. Arch Surg 98:24–30PubMedGoogle Scholar
  211. Hayduk K, Kaufmann W (1973) Ektope paraneopla- stische Endokrinopathien mit Störungen des Wasser- und Elektrolythaushaltes. Klin Wochenschr 51:361–376PubMedGoogle Scholar
  212. Hazel van W (1940) Joint manifestations associated with intrathoracic tumors. J Thorac Cardiovasc Surg 9:495–505Google Scholar
  213. Heath H, Weller RE, Mundy GR (1980) Canine lymphosarcoma : a model for study of the hypercalcemia of cancer. Calcif Tissue Res 30:127–133Google Scholar
  214. Hedinger Chr (1955) Endokrine Begleiterscheinungen der Karzinoide. Schweiz Z Allg Pathol Bakt 18:1184–1188Google Scholar
  215. Heersche JNM, Marcus R, Aurbach GD (1974) Calcitonin and the formation of 3´.5´-AMP in bone and kidney. Endocrinology 94:241–247PubMedGoogle Scholar
  216. Hemley SD, Arida EJ, Finby N (1963) Cushing’s syndrome associated with bronchogenic carcinoma. Radiology 80:11–16PubMedGoogle Scholar
  217. Hennen G (1966) Thyrotropin-like factor in a nonendocrine cancer tissue. Arch Int Physiol Biochem 74:701Google Scholar
  218. Hennen G (1967) Characterization of a thyroid-stimu- lating factor in human cancer tissue. J Clin Endocrin 27:610Google Scholar
  219. Herzberg JJ (1976) Paraneoplasien bei Bronchialkarzinom als Beispiel der systemischen Manifestation einer pulmonalen Erkrankung. Therapiewoche 26:8430–8434Google Scholar
  220. Herzberg JJ (1977) Paraneoplastische Syndrome der Haut. Dtsch Ärztebl 74:59–66Google Scholar
  221. Hesch RD (1980) Extraglanduläre Ursachen des Hyperparathyreoidismus. Dtsch Med Wochenschr 105:448–450PubMedGoogle Scholar
  222. Heuck F (1970) Die radiologische Erfassung des Mineralgehaltes des Knochens. In : Handbuch Med Radiologie Bd IV/1. Springer, Berlin Heidelberg New YorkGoogle Scholar
  223. Heuck F (1973) Die Struktur des Knochens bei Osteoarthropathie hypertrophicans (Pierre-Marie- Bamberger Syndrom). 53. Tagung der Dtsch Rönt- genges 1972. Thieme, Stuttgart, S 56–58Google Scholar
  224. Heuck F (1976) Allgemeine Radiologie und Morphologie der Knochenkrankheiten. In : Handbuch Med Radiologie, BdV/1. Springer, Berlin Heidelberg New YorkGoogle Scholar
  225. Heuck F, Vanselow K (1980) Radiologische Methoden. In: Handbuch der Inn. Medizin, Bd VI/1 A. Springer, Berlin Heidelberg New YorkGoogle Scholar
  226. Heusden van EG, Nauta Z (1957) Recovery from Pierre Marie’s hypertrophic osteoarthropathy. NT Geneesk 101:1357–1359Google Scholar
  227. Hillyard CJ, Coombes RC, Greenberg PB, Galante LS, MacIntyre I (1976) Calcitonin in breast and lung cancer. Clin Endocrinol 5:1Google Scholar
  228. Högler F (1920) Über Akropachie. Wien Arch Inn Med 1:35Google Scholar
  229. Hövels O, Stephan U (1962) Das Krankheitsbild der idiopathischen Hypercalcämie, eine chronische Vitamin-D-Intoxikation. Ergebn Inn Med Kinderheilkd NF 18:116–195Google Scholar
  230. Hoffmann V (1919) Ein Beitrag zur Kenntnis der Osteoarthropathie hypertrophiante pneumonique (P Marie). Arch Klin Med 130:201–211Google Scholar
  231. Holling HE (1967) Pulmonary hypertrophic osteoarthropathy. Ann Intern Med 66:232–234PubMedGoogle Scholar
  232. Holling HE, Brodey RS (1961) Pulmonary hypertrophic osteoarthropathy. J Am Med Assoc 178:977–982Google Scholar
  233. Holling HE, Brodey RS, Boland C (1961) Pulmonary hypertrophic osteoarthropathy. Lancet II : 1269–1274Google Scholar
  234. Holling HE, Danielson GK, Hamilton RW, Blake- more WS, Brodey RS (1963) Hypertrophic pulmonary osteoarthropathy. J Thorac Cardiovasc Surg 46:310–321PubMedGoogle Scholar
  235. Hollis WC (1967) Hypertrophic osteoarthropathy secondary to upper-gastrointestinal-tract neoplasm. Ann Intern Med 66:125–130PubMedGoogle Scholar
  236. Holmes HH, Bauman E, Ragan CH (1950) Symptomatic arthritis due to hypertrophic pulmonary osteoarthropathy in pulmonary neoplastic disease. Ann Rheum Dis 9:169–173PubMedGoogle Scholar
  237. Holmes JR (1961) A case of hypertrophic pulmonary osteoarthropathy in a mare. Vet Rec 73:333Google Scholar
  238. Hough A, Seyberth H, Oates J, Hartman W (1977) Changes in bone and bone marrow of rabbits bearing the VX-2 carcinoma. Am J Bathol 87:537–552Google Scholar
  239. Howard JE (1965) Case record of the Massachusetts General hospital Case 38–1965. N Engl J Med 273:494–504Google Scholar
  240. Howell DS (1979) Hypertrophic osteoarthropathy. In: McCarty DJ (ed) Arthritis and allied disorders. Lea & Febiger, PhiladelphiaGoogle Scholar
  241. Humes JL, Cupo JJ, Strausser HR (1974) Effects of indometacin on Moloney sarcoma virus-induced tumors. Prostaglandins 6:463PubMedGoogle Scholar
  242. Hung W, Blizzard RM, Migeon CJ (1963) Precocious puberty in a boy with hepatoma and circulating gonadotropin. J Pediatr 63:895PubMedGoogle Scholar
  243. Hymes AC, Doe RP (1962) Adrenal function in cancer of the lung with and without Cushing’s syndrome. Am J Med 33:398–407PubMedGoogle Scholar
  244. Ive FA (1963) Metastatic carcinoma of cervix with acantosis nigricans, bullous pemphigoid and hypertrophic pulmonary osteoarthropathy. Proc R Soc Med 56:910PubMedGoogle Scholar
  245. Jaffe BM, Parker CW, Philpott GW (1971) Immuni- chemical measurement of prostaglandin or prostaglandin-like activity from normal and neoplastic tissues in culture. Surg Forum 22:90PubMedGoogle Scholar
  246. Jaffé HL (1958) Tumor and tumorous conditions of the bones and joints. Lea & Febiger, PhiladelphiaGoogle Scholar
  247. Jaffee IS (1964) Nasopharyngeal carcinoma - Unusual case reports. Arch Otolaryng 80:450PubMedGoogle Scholar
  248. Jallut O, Koenig PM, Labhart A (1962) Akropachie bei thyreohypophysärem Syndrom (Trommelschle- gelfinger, Osteoarthropathia hypertrophicans, maligner Exophthalmus und lokalisiertes prätibiales Myxödem). Schweiz Med Wochenschr 92:255PubMedGoogle Scholar
  249. Jepson RP, Jordan A, Levell MJ (1956) Urinary steroid response to operation. Br J Surg 43:390–395PubMedGoogle Scholar
  250. Jerusalem F (1972) Paraneoplastische Syndrome und Krankheitsbilder. Nervenarzt 43:169–175PubMedGoogle Scholar
  251. Jesserer H (1957) Das Krankheitsbild der idiopathischen Hyperkalkurie. Dtsch Med Wochenschr 82:943–946, 961PubMedGoogle Scholar
  252. Johnston IDA, Hudgson P, Shuster S, Gudmundson TV, Joplin GF, Williams ED, Woodhouse NJY, Galante L, MacIntyre I (1968) A calcitonin-secreting thyroid carcinoma. Lancet II : 63Google Scholar
  253. Jones JE, Shane SR, Gilbert E, Flink EB (1969) Cushing’s syndroma induced by the ectopic production of ACTH by a bronchial carcinoid. J Clin Endocrinol Metab 29:1PubMedGoogle Scholar
  254. Juster M, Crespo I (1969) Estudio microrradiografico en la osteoartropatia hipertrofiante neumica o enfermedad de Pierre Marie. Rev Interamer Radiol 4:44–58Google Scholar
  255. Kahn CR, Rosen SW, Weintraub BD, Fajans SS, Gordon P (1977) Ectopic production of chorionic gonadotropin and its subunits by islet-cell tumors. A specific marker for malignancy. N Engl J Med 297:565PubMedGoogle Scholar
  256. Kaplan EC, Arnaud CD, Hill BJ, Peskin GW (1970) Adrenal medullary calcitonin-like factor; a key to multiple endocrine neoplasia, Type 2? Surgery 28:146Google Scholar
  257. Karim SMM, Rao B (1976) Prostaglandins and tumors. In : Karim (ed) Prostaglandins : Physiological, pharmacological, and pathological aspects. MTP Press, LancesterGoogle Scholar
  258. Katz A, Kaplan L, Massry SG, Heller R, Plotkin D, Knight J (1970) Primary hyperparathyroidism in patients with breast carcinoma. Arch Surg 101:582PubMedGoogle Scholar
  259. Kay CJ, Rosenberg MA (1974) Positive 99m Tc-po- lyphosphate bone scan in a case of secondary hypertrophic osteoarthropathy. J Nucl Med 15:312–313PubMedGoogle Scholar
  260. Kay CJ, Rosenberg MA, Burd R (1974) Hypertrophic osteoarthropathy and childhood Hodgkin’s disease. Pediatr Radiol 112:177–178Google Scholar
  261. Keats TE, Bagnall WS (1954) Chronic idiopathic osteoarthropathy. Radiology 62:841–844PubMedGoogle Scholar
  262. Kelley RM, Baker WH (1965) The role of progesterone in human endometrial cancer. Cancer Res 25:1190–1192PubMedGoogle Scholar
  263. Kennedy JH, Williams MJ, Sommers SC (1964) Cushing’s syndrome and lung cancer: Pituitary crook cell hyperplasia in pulmonary oat cell carcinoma. Ann Surg 160:90PubMedGoogle Scholar
  264. Kepler EJ (1933) Polyglandular dyscrasias involving abnormalities of sexual characteristics. Proc Staff Meetings Mayo Clin 8:102Google Scholar
  265. Kepler EJ, Dockerty MB, Priestley JT (1944) Adrenallike ovarian tumor associated with Cushing’s syndrome (so-called masculino-ovoblastoma, luteoma, hypernephroma, adrenal cortical carcinoma of the ovary). Am J Obstet Gynecol 47:43Google Scholar
  266. Keynes WM, Jewll D, Till AS (1969) ACTH and calcitonin producing medullary carcinoma of the thyroid gland. In: Abstracts of 2nd International Symposium on Calcitonin. Heinemann, LondonGoogle Scholar
  267. Kistner RW, Griffiths CT, Craig JM (1965) Use of progestational agents in the management of endometrial cancer. Cancer 18:1563PubMedGoogle Scholar
  268. Klein DC, Raisz LG (1970) Prostaglandins: Stimulation of bone resorption in tissue culture. Endocrinology 86:1436–1440PubMedGoogle Scholar
  269. Kleinsmith LJ, Pierce GB (1964) Multipotentiality of single embryonal carcinoma cells. Cancer Res 24:15Google Scholar
  270. Kline EM (1945) Hypertrophic osteoarthropathy. Am J Roentgenol 54:519–523Google Scholar
  271. Knill-Jones RP, Buckle RM, Parsons V, Calne RY, Williams R (1970) Hypercalcemia and increased parathyroid hormone activity in a primary hematoma. N Engl J Med 282:704–708PubMedGoogle Scholar
  272. Kohler FP (1959) Ungewöhnliche Komplikation eines Prostatakarzinoms (Aldosteronismus). Wien Med Wochenschr 109:479PubMedGoogle Scholar
  273. Kohout E (1966) Serum calcium levels and parathyroid glands in malignant disorders. Cancer 19:925–934PubMedGoogle Scholar
  274. Kollbrunner F (1948) Gutartiger Riesenzelltumor mit maligner Entartung nach 4 Jahren und Ostéoarthropathie hypertrophiante pneumonique durch Lungenmetastase. Oncologia 1:153–164Google Scholar
  275. Kovach RD, Kyle LH (1958) Cushing’s syndrome and bronchogenic carcinoma. Am J Med 24:981PubMedGoogle Scholar
  276. Kracht J (1967) Pathologie der ektopisch hormonbildenden Tumoren. Verh Dtsch Ges Inn Med 73:488PubMedGoogle Scholar
  277. Kracht J (1968) Pathologie der ektopisch hormonbildenden Geschwülste. Med Klin 63:41–46PubMedGoogle Scholar
  278. Kracht J (1970) Hormonbildende Lungengeschwülste. Kongr Ber Nordd Ges Tbk Lungenkrht 11:108–120Google Scholar
  279. Kracht J (1974) Paraneoplastische Endokrinopathien. In: Lindenschmidt O (Hrsg) Pathophysiologische Grundlagen der Chirurgie, 2. Aufl. Thieme, StuttgartGoogle Scholar
  280. Kracht J, Hantschmann N (1961) Syntropien des Cushing-Syndroms. Acta Endocrinol 38:490–514PubMedGoogle Scholar
  281. Kracht J, Pfotenhauer R (1966) Die extrahypophysären kortitropen Geschülste. 12. Symp Dtsch Ges Endokrinol S 274–278Google Scholar
  282. Krishnamurthy GT, Brickman AS, Blahd WH (1977) Technetium-99m-Sn-Pyrophosphate pharmacokinetics and bone image changes in parathyroid disease. J Nucl Med 18:236–242PubMedGoogle Scholar
  283. Kühne K, Gerstel G (1932) Klinisch-röntgenologische und pathologisch-histologische Befunde bei einem Fall von allgemeiner Osteophytose (Ostéoarthropathie hypertrophiante pneumique). Fortschr Röntgenstr 46:662–670Google Scholar
  284. Kunkel G (1971) Hypertrophe pulmonale Osteoarthropathie. Med Klin 66:1486PubMedGoogle Scholar
  285. Labbé M, Renault P (1928) L-ostéodermopathie hypertrophiante. Presse Méd 36:545Google Scholar
  286. Labhart A (1978) Klinik der inneren Sekretion, 3. Aufl. Springer, Berlin Heidelberg New YorkGoogle Scholar
  287. Lafferty FW (1966) Pseudohyperparathyroidism. Medicine (Baltimore) 45:247–260Google Scholar
  288. Lamache A, Bourel M, Chevrel ML, Richier JL (1956) La periostose engainante de l’ostéoarthropathie pneumonique de Pierre-Marie. Rev Rhum 23:584–589PubMedGoogle Scholar
  289. Lamberg BA, Pekonen R, Frick MH (1964) Hypercalcemia in renal carcinoma. Report of a case. Acta Med Scand 176:187–194PubMedGoogle Scholar
  290. Lasserre Ch (1933) A propos des ostéopathies hyper- trophiantes. Presse Med 41:1425Google Scholar
  291. Law DH, Liddle GW, Scott HW, Tauber StD (1965) Ectopic production of multiple hormones by a single malignant tumor. N Engl J Med 273:292–296PubMedGoogle Scholar
  292. Leading Article (1976) Ectopic secretion by tumors. Br Med J 1:1300Google Scholar
  293. Lee JC, Yamauchi H, Hopper J (1966) The association of cancer and the nephrotic syndrome. Ann Intern Med 64:41–51PubMedGoogle Scholar
  294. Leighton RL, Stoyak JM (1953) Hypertrophic pulmonary osteoarthropathy resulting from metastasis to the lungs in dogs. J Amer Vet MA 123:437Google Scholar
  295. Lembeck F (1953) 5-Hydroxytryptamine in a carcinoid tumour. Nature 172:910–911Google Scholar
  296. Levine L (1977) Chemical carcinogens stimulate canine kidney (MDCK) cells to produce prostaglandins. Nature 268:447PubMedGoogle Scholar
  297. Levine L, Hinkle PM, Voelkel EF, Tashjian AH (1972) Prostaglandin production by mouse fibrosarcoma cells in culture: Inhibition by indomethacin and aspirin. Biochem Biophys Res Comun 47:888–896Google Scholar
  298. Levine RJ, Metz SA (1974) A classification of ectopic hormone-producing tumors. Ann NY Acad Sci 230:533–546PubMedGoogle Scholar
  299. Lewis MG, Loughridge LW, Phillips TM (1971) Immunological studies in nephrotic syndrome associated with extrarenal malignant disease. Lancet II:134–135Google Scholar
  300. Leyton O, Turnbull HM, Bratton AB (1931) Primary cancer of the thymus with pluriglandular disturbance. J Pathol Bact 34:634Google Scholar
  301. Liddle GW, Givens JR, Nicholson WE, Island DP (1965) The ectopic ACTH Syndrome. Cancer Res 25:1057PubMedGoogle Scholar
  302. Lipsett M, Odell WD, Rosenberg LE (1964) Humoral syndromes associated with nonendocrine tumors. Ann Intern Med 61:733–756PubMedGoogle Scholar
  303. Locke EA (1915) Secondary hypertrophic osteoarthropathy and its relation to simple clubfingers. Arch Intern Med 15:659–713Google Scholar
  304. Lockwood CH (1958) Studies of adrenal cortical function in 3 cases of carcinoma. Can Med Assoc J 79:728PubMedGoogle Scholar
  305. Logue JT (1953) Osteoarthropathy and simple clubbing. US Armed Forces MJ 4:1627–1631Google Scholar
  306. Lorenz FN, Custer GSt (1965) ACTH producing metastases from carcinoma of the esophagus. Ann Intern Med 62:1017–1022Google Scholar
  307. Louyot, Castelain (1941) L’ostéopathie hypertrophiante pneumonique maladie de Pierre Marie. Rev Rhumat 8:514–544Google Scholar
  308. Lovell RRH (1950) Observations on structure of clubbing fingers. Clin Sci 9:299–321Google Scholar
  309. Ludwig J, Grier MW, Hoffman HN, McGill DB (1975) Calcified mixed malignant tumor of the liver. Arch Pathol Lab Med 99:162–166Google Scholar
  310. Lükö G, Tóth F (1958) Über „Osteoarthropathie hypertrophiante pneumonique“ (Bamberger-P. Marie) bei benignen Lungentumoren (Leiomyom). Bruns’ Beitr Klin Chir 196:19–31Google Scholar
  311. MacPhee IW (1959) Cushing’s syndrome associated with carcinoma of the bronchus. Br J Surg 45:456Google Scholar
  312. Mankowsky BN, Heinismann JI, Czerny LI (1934) Osteopathia dysplastica familiaris. Fortschr Röntgenstr 50:542–549Google Scholar
  313. Margineanu N (1965) L’osteoartropatia ipertrofiz- zante pneumica. Nunt Radiol 31:28–34PubMedGoogle Scholar
  314. Marie J, See G (1951) Hydrocéphalie aigné bénigne du nourrisson après ingestion d’une dose massive, unique de vitamines A et D; (accident d’hyper- vitaminose A aigné). Sem Hôp Paris 27:1744–1746PubMedGoogle Scholar
  315. Marie P (1890) De l’ostéoarthropathie hypertrophiante pneumonique. Rev Méd Paris 10:1–36Google Scholar
  316. Martini GA, Hagemann JE (1956) Über Fingernagelveränderungen bei Leberzirrhose als Folge veränderter peripherer Durchblutung. Klin Wochenschr 34:25PubMedGoogle Scholar
  317. Massalongo R, Gasperini U (1913) Sulla osteo-ar- thropathia ipertrofica pneumonica. Policlinico 20:433–448Google Scholar
  318. Massaro DJ, Owen JA (1962) Persistent hypercalcemia associated with bronchogenic carcinoma and primary chief-cell hyperplasia of the parathyroids. Am Rev Respir Dis 85:727–734PubMedGoogle Scholar
  319. Mather G, Low D (1953) Chronic pulmonary osteoarthropathy in the dog. J Amer Vet MA 122:167Google Scholar
  320. Matthias M (1976) Das paraneoplastische Syndrom. Z Ges Inn Med 31:772–782PubMedGoogle Scholar
  321. Maurach R, Strian F (1980) Polyneuropathien als Begleiterkrankungen bei malignen Tumoren. Med Klin 75:678–682PubMedGoogle Scholar
  322. Mavligit GM, Cohen JL, Sherwood LM (1971) Ectopic production of parathyroid hormone by carcinoma of the breast. N Engl J Med 285:154–156PubMedGoogle Scholar
  323. Mayer JS, Abdel-Bari W (1968) Granules and thyro- calcitonin-like activity in medullary carcinoma of the thyroid gland. N Engl J Med 278:530Google Scholar
  324. McCance RA (1947) Osteomalacia with Looser’s nodes (Milkman syndrome) due to a raised resistance to vitamin D acquired about the age of 15 years. Q J Med (NS) 61:33–46Google Scholar
  325. McCroskery PA, Harris ED (1973) Rapid tumor colla - genase : purification from homogenates of fresh tissue. Fed Proc 32:614Google Scholar
  326. McPherson J (1965) Reversion in hamster cells transformed by Rous sarcoma virus. Science 148:25Google Scholar
  327. McPherson GD (1965) Stable calcium isotopes as tracers in studies of mineral metabolism. Acta Orthop Scand [Suppl 78]Google Scholar
  328. McSwiney RR, Mills IH (1956) Hypercalcaemia due to sacoidosis - treatment with cortisone. Lancet 1:862–866Google Scholar
  329. Meador CK, Liddle DW, Island DP, Nicholson WE, Lucas CP, Nuckton JG, Luetscher J (1962) Cause of Cushing’s syndrome in patients with tumor arising from “nonendocrine” tissue. J Clin Endocrinol Metab 22:693–703PubMedGoogle Scholar
  330. Melick RA, Martin TJ, Hicks JD (1972) Parathyroid hormone production and malignancy. Br Med J 11:204–205Google Scholar
  331. Melvin KEW, Tashjian AH (1968) The syndrome of excessive thyrocalcitonin produced by medullary carcinoma of the thyroid gland. Proc Natl Acad Sci USA 59:1216PubMedGoogle Scholar
  332. Melvin KEW, Tashjian AH, Cassidy CE, Givens JR (1970) Cushing’s syndrome caused by ACTH- and Calcitonin-secreting medullary carcinoma of the thyroid. Metabolism 19:831–838PubMedGoogle Scholar
  333. Mendlowitz M (1941) Measurements of blood flow and blood pressure in clubbing fingers. J Clin Invest 20:113PubMedGoogle Scholar
  334. Mendlowitz M (1942) Clubbing and hypertrophic osteoarthropathy. Medicine 21:269–306Google Scholar
  335. Mendlowitz M, Leslie A (1942) Experimental simulation in dog of cyanosis and hypertrophic osteoarthropathy which are associated with congenital heart disease. Am Heart J 24:141–152Google Scholar
  336. Menguy R (1969) Pseudohyperparathyroidism due to malignant melanoma. Surg Clin North Amer 49:49Google Scholar
  337. Meunier P, Vignon G, Bernard J, Edouard C, Coupron P, Porte J (1972) La lecture quantitative de la biopsie osseuse moyen de diagnostic et d’étude de 106 hyperparathyroidies primitives, secondaires et paraneoplasiques. Rev Rhumat 39:635–644Google Scholar
  338. de Meyer G, Sarasin P (1950) Un cas d’ostéoarthrop- athie hypertrophiante pneumonique de Pierre Marie associée à une cirrhose biliaire. Schweiz Med Wochenschr 80:1230PubMedGoogle Scholar
  339. Milhaud G, Calmettes C, Taboulet J (1974) Hypersecretion of calcitonin in neoplastic conditions. Lancet 1:462PubMedGoogle Scholar
  340. Miller EJ, Martin GR, Piez KA, Powers MJ (1967) Characterization of chick bone collagen and compositional changes associated with maturation. J Biol Chem 242:5481PubMedGoogle Scholar
  341. Miller ER (1939) Carcinome of the thymus, with marked pulmonary osteo-arthropathy. Radiology 32:651–660Google Scholar
  342. Miller SP, Sanchez-Avalos J, Stefanski T, Zuckermand L (1967) Coagulation disorders in cancer. Cancer 20:1452PubMedGoogle Scholar
  343. Mills JA (1963) Connective tissue disease associated with neoplastic disease. J chronic Dis 16:797–811PubMedGoogle Scholar
  344. Minkus P, Dieterle P (1979) Paraneoplastische Endo- krinopathien. Med Klin 74:1415–1421PubMedGoogle Scholar
  345. Moolten SE (1970) Hyperparathyroidism in cancer of the bronchus. J Med Soc NJ 67:474–476Google Scholar
  346. Moore FD, Steenburg RW, Ball MR, Wilson GM, Myrden JA (1955) Studies in surgical endocrinology: 1. The urinary excretion of 17-hydroxycorti- coids and associated metabolic changes, in cases of soft tissue trauma of varying severity and in bone trauma. Ann Surg 141:145–174PubMedGoogle Scholar
  347. Morawetz F (1973) Klinik der Paraneoplasien. In: Mlczoch F, Seidel H (Hrsg) Aktuelle Fragen der Lungenpathologie. Thieme, StuttgartGoogle Scholar
  348. Morgan AG, Walker WC, Mason MK, Herlinger H, Losowsky MS (1972) A new syndrome associated with hepatocellular carcinoma. Gastroenterology 63:340–345PubMedGoogle Scholar
  349. Müller OA (1981) Diagnose und Prognose des Cushing-Syndroms. Lebensversicherungsmedizin. Z Diagn Progn 33:89–93Google Scholar
  350. Muheim G, Donath A, Rossier AB (1973) Serial scintigrams in the course of ectopic bone formation in paraplegic patients. Am J Roentgenol 118:865–869Google Scholar
  351. Mundy GR, Raisz LG, Cooper RA, Schlechter GP, Salmon SE (1974) Evidence for the secretion of an osteoclast stimulating factor in myeloma. N Engl Med 291:1041–1046Google Scholar
  352. Mundy GR, Eilon G (1977) Direct resorption of bone by cultured human breast cancer cells (abstract). Clin Res 25:410AGoogle Scholar
  353. Mundy GR, Rick ME, Turcotte R, Kowalski MA (1978) Pathogenesis of hypercalcemia in lymphosarcoma cell leukemia. Am J Med 65:600–606PubMedGoogle Scholar
  354. Munson PL (1961) Biological assay of parathyroid hormone. In: Greep, Talmage (eds) The Parathyroids. Thomas, Springfield/IIIGoogle Scholar
  355. Munson PL, Tashjian AH, Levine L (1965) Evidence for parathyroid hormone in nonparathyroid tumors associated with hypercalcemia. Cancer Res 25:1062–1067PubMedGoogle Scholar
  356. Murray RO, Jacobson HG (1977) The Radiology of Skeletal Diseases, 2nd ed. Churchill-Livingstone, Edinburg-LondonGoogle Scholar
  357. Nagel GA (1971) Immunosuppression: ein paraneoplastisches Syndrom. Schweiz Med Wochenschr 101:470–474PubMedGoogle Scholar
  358. Nagel M (1971) Paraneoplastische Endokrinopathien. Langenbecks Arch Chir 329:464PubMedGoogle Scholar
  359. Nesson HR, Sproul LE, Reiman AS, Schwartz WB (1963) Adrenal steroids in the treatment of idio- pathie nephrotic syndrome in adults. Ann Intern Med 58:268–277Google Scholar
  360. Nichols J, Warren JC, Mantz FA (1962) ACTH-like excretion from carcinoma of the ovary. J Am Med Assoc 182:713–718Google Scholar
  361. Nielsen SW, Bishop EJ (1953) Pulmonary osteoarthropathy in a lion. No Amer Vet 34:867Google Scholar
  362. Nörgaard F (1965) Earliest roentgenological changes in polyarthritis of rheumatoid type: rheumatoid arthritis. Radiology 84:325–329Google Scholar
  363. Norris EH (1938) Adenoblastoma : a malignant ovarian tumor associated with endocrinological effects. Am J Cancer 32:1Google Scholar
  364. Oelz O (1977) Prostaglandin-Thromboxan System und Thrombozytenfunktion. Acta Med Austriaca [Suppl 4] 85Google Scholar
  365. Oelz O, Knapp HR, Roberts LJ, Oelz R, Sweetman BJ, Oates JA, Reed PW (1978) Calcium-dependent stimulation of thromboxane and prostaglandine biosynthesis by ionophorese. Adv Prostaglandin Thromboxane Res 3:147–158PubMedGoogle Scholar
  366. O’Grady AS, Morse LJ, Lee JB (1965) Parathyroid hormone-secreting renal carcinoma associated with hypercalcemia and metabolic alkalosis. Ann Intern Med 63:858–868PubMedGoogle Scholar
  367. Omenn GS (1970) Ectopic polypeptid hormone production by tumors. Ann Intern Med 72:136–138PubMedGoogle Scholar
  368. Omenn GS (1971) Ectopic hormone syndromes associated with tumors in childhood. Pediatrics 47:613–622PubMedGoogle Scholar
  369. Omenn GS, Roth SI, Baker WH (1969) Hyperparathyroidism associated with malignant tumors of nonparathyroid origin. Cancer 24:1004–1012PubMedGoogle Scholar
  370. O’Riordan JLH, Blanshard GP, Moxham A, Nabarro JDN (1966) Corticotrophin secreting carcinomas. QJ Med 35:137Google Scholar
  371. Pascuzzi CA, Parkin TW, Bruwer AJ, Edwards JE (1957) Hypertrophic osteoarthropathy associated with primary rhabdomyosarcoma of the heart. Mayo Clin Proc 32:30Google Scholar
  372. Pattison JD, Beck E, Miller WB (1951) Hypertrophic osteoarthropathy in carcinoma of lung. JAMA 146:783–787Google Scholar
  373. Penitschka W (1938) Über Osteoarthropathie hypertrophiante (Bamberger-Marie). Bruns Beitr Klin Chir 167:75–109Google Scholar
  374. Pergola F, Galian A, Bernades P, Cachin M (1964) Hypercorticisme et cancer bronchique alcalose hy- pokaliémique révelatrice. Soc Méd Hôp (Paris) 115:879Google Scholar
  375. Perkins PJ (1978) Delayed onset of secondary hypertrophic osteoarthopathy. Am J Roentgenol 130:561–562Google Scholar
  376. Peskar BM (1981) Bedeutung der Prostaglandine für Tumorwachstum und Tumorsymptomatik. Med Klin 76:26–31Google Scholar
  377. Peyman MA (1959) Acholasia of the cardia, carcinoma of the esophagus and hypertrophic osteoarthropathy. Br Med J 1:23PubMedGoogle Scholar
  378. Pfeffer KH, Brandenburg W, Frommhold W (1961) Cushing Syndrom und Bronchialkarzinom mit funktionellen Störungen des Hypophysenvorder- lappens. Dtsch Med Wochenschr 86:1298PubMedGoogle Scholar
  379. Pflüger K-H, Gropp C, Havemann K (1982) Ectopi- cally produced Calcitonin in human hemoblas- toses. Klin Wochenschr 60 :667–672PubMedGoogle Scholar
  380. Phemister DB (1917) Chronic lung abszess with hypertrophic osteoarthropathy. Surg Clin (Chicago) 1:381–389Google Scholar
  381. Pierce TH, Weir DG (1973) Hypertrophie osteoarthropathy associated with a non-metastasising carcinoma of the oesophagus. J Irish Med Assoc 66:160–162Google Scholar
  382. Pimstone BL, Uys GJ, Vogelpoel L (1972) Studies in a case of Cushing’s syndrome due to an ACTH- producing thymic tumor. Am J Med 53:521PubMedGoogle Scholar
  383. Pirschei J, Metzger HOFJ, Wissmann C (1978) Zur Metastasierung maligner Tumoren in die Skelett- peripherie. Fortschr Röntgenstr 129:621–626Google Scholar
  384. Plenk A, Pretl K (1953) Peripheres endobronchiales Plasmocytom der Lunge mit Osteopathie hypertro- phicans. Wien Med Wochenschr 103:450–451PubMedGoogle Scholar
  385. Plonk JW, Feldman JM (1974) Carcinoid arthropathy. Arch Intern Med 134:651–654PubMedGoogle Scholar
  386. Pompecki R, Schröder G, Garbrecht M, Frahm H (1978) Carcinoembryonales Antigen (CEA) in Plasma bei Patienten mit metastasierendem Mammakarzinomunter endokriner und zytostatischer Therapie. Dtsch Med Wochenschr 103:620–622PubMedGoogle Scholar
  387. Ponchon Y, Chelloul N, Roujeau J (1969) Contribution a l’étude anatomo-pathologique de l’hip- pocratisme digital. Sem Hôp Paris 45:2604–2611PubMedGoogle Scholar
  388. Powell D, Singer FR, Murray TM, Minkin C, Potts JT (1973) Nonparathyroid humoral hypercalcemia in patients with neoplastic diseases. N Engl J Med 289:176–181PubMedGoogle Scholar
  389. Powles TJ, Clark SA, Easty DM, Neville AM (1973) The inhibition by aspirin and indometacin of osteolytic tumor deposits and hypercalcaemia in rats with Walker tumor, and its possible application to human breast cancer. Br J Cancer 28:316PubMedGoogle Scholar
  390. Powles TJ, Dowsett M, Easty DM, Easty GC, Neville AM (1976) Breast-cancer osteolysis, bone metastases, and antiosteolytic affect of aspirin. Lancet I:608–610Google Scholar
  391. Prader A, Illig R, Uehlinger E, Stalder G (1959) Rachitis infolge Knochentumors. Helv Paediatr Acta 14:554–565PubMedGoogle Scholar
  392. Prunty FTG, Brooks RV, Dupré J, Gimlette TMD, Hutchinson JSM, McSwiney RR, Mills IH (1963) Adrenocortical hyperfunction and potassium metabolism in patients with “non-endocrine” tumors and Cushing’s syndrome. J Clin Endocrinol Metab 23:737–746PubMedGoogle Scholar
  393. Pusch HJ, Koch W, Wegener M, Fährer E (1976) Paraneoplastische Syndrome in der inneren Medizin. Med Welt NF 27:2372–2376Google Scholar
  394. Raisz LG (1973) Prostaglandins and the hypercalcemia of cancer. N Engl J Med 289:214PubMedGoogle Scholar
  395. Raisz LG, Koolemans-Beynen AR (1974) Inhibition of bone collagen synthesis by prostaglandin E2 in organ culture. Prostaglandins 8:374Google Scholar
  396. Raisz LG, Mundy GR, Luben RA (1974) Skeletal reactions to neoplasms. Ann NY Acad Sci 230:473–475PubMedGoogle Scholar
  397. Raisz LG, Sandberg AL, Goodson JM, Simmons HA, Mergenhagen SE (1974) Complement-dependent stimulation of prostaglandin synthesis and bone resorption. Science 185:789–791PubMedGoogle Scholar
  398. Raisz LG, Luben RA, Mundy GR, Dietrich JW, Horton JE, Trummel CL (1975) Effect of osteoclast activating factor from human leukocytes on bone metabolism. J Clin Invest 56:408–413PubMedGoogle Scholar
  399. Raisz LG, Dietrich JW, Simmons HA, Seyberth HW, Hubbard W, Dates JA (1977) Effect of prostaglandin endoperoxides and metabolites on bone resorption in vitro. Nature 267:532–534PubMedGoogle Scholar
  400. Raker JW, Henneman PD, Graf WS (1962) Coexisting primary hyperparathyroidism and Cushing’s syndrome. J clin Endocrinol 22:273–280Google Scholar
  401. Ramsdell CM, Kelley WN (1973) The clinical significance of hypouricemia. Ann Intern Med 78:239–242PubMedGoogle Scholar
  402. Rao LG, Brunette DM, Heersche JNM (1977) Parathyroid hormone and prostaglandin E1-response in a selected population of bone cells after repeated subculture and storage at - 80 C. Endocrinology 100:1233–1241PubMedGoogle Scholar
  403. Rao GM, Guruprakash GH, Poulose KP, Bhaskar G (1979) Improvement in hypertrophic pulmonary osteoarthropathy after radiotherapy to metastasis. Am J Roentgenol 133:944–946Google Scholar
  404. Rasmussen B, Roesdahl K, Lindgren P (1978) Parathyroid hormone and calcitonin in serum of patients with mammary carcinoma. Acta Radiol Oncol 17:269–276Google Scholar
  405. Ratzenhofer M (1977) Über enterale Hyperplasien und Geschwülste der disseminierten endokrinen (para- krinen) Hellen Zellen Feyerters unter Berücksichtigung amphikriner Zellwanderungen. Verh Dtsch Ges Pathol 41:7–21. G Fischer, Stuttgart-New York 1977Google Scholar
  406. Ratzenhofer M, Lembeck F (1954) Über den Gehalt an 5-Oxytryptamin in Karzinoiden des Darmstraktes. Z Krebsforsch 60:169–195PubMedGoogle Scholar
  407. Renton P, Shaw DG (1976) Hypophosphatemic osteomalacia secondary to vascular tumors of bone and soft tissue. Skeletal Radiology 1:21–24Google Scholar
  408. Rees LH, Ratcliffe JG (1974) Ectopic hormone production by non-endocrine tumours. Clin Endocrinol 3:263–299Google Scholar
  409. Reiser U, Heuck F, Lichtenau L (1980) Untersuchungen der Mineraltopographie am menschlichen Wirbelkörper mit der Röntgen-Computer-Tomogra- phie. Radiologe 20:554–557PubMedGoogle Scholar
  410. Rex MAE (1959) Effect of surgical intervention in case of chronic pulmonary osteoarthropathy in dog. Vet Rec 71:409–411Google Scholar
  411. Ribelin WE, Bailey WS (1958) Esophageal sarcomas associated with Spirocerca lupi infection in dog. Cancer 11:1242–1246PubMedGoogle Scholar
  412. Ricklin P (1955) Gelenkbeschwerden als Frühsymptom des Bronchuskarzinoms. Ein Beitrag zur Kenntnis der Ostéoarthropathie hypertrophiante pneumonique (Bamberger-Marie). Schweiz Med Wochenschr 85:764–767PubMedGoogle Scholar
  413. Ricklin P (1955) Über die Ostéoarthropathie hypertrophiante pneumonique. Erg Chir Orthop 39:295–326PubMedGoogle Scholar
  414. Rieche K (1968) Blutgerinnungsstörungen bei menschlichen Geschwulsterkrankungen. Arch Geschwulstforsch 32:262PubMedGoogle Scholar
  415. Riegger G, Reinhard U, Raff U, Hayduk K (1976) Rezidivierende Lungenembolien als Erstsymptom eines Mamma-Karzinoms. Med Welt 27:35–37PubMedGoogle Scholar
  416. Riggs BL, Sprague RG (1961) Association of Cushing’s syndrome and neoplastic disease. Arch Intern Med 108:85Google Scholar
  417. Riggs BL, Arnaud CD, Reynolds JC, Smith LH (1971) Immunologic differentiation of primary hyperparathyroidism due to nonparathyroid cancer. J Clin Invest 50:2079–2083PubMedGoogle Scholar
  418. Rimoin DL (1965) Pachydermoperiostosis (idiopathic clubbing and periostosis) : genetic and physiologic considerations. New Engl J Med 272:923PubMedGoogle Scholar
  419. Ringe J-D (1981) Das Hypercalcämie-Syndrom. Dtsch Med Wochenschr 106:92–93PubMedGoogle Scholar
  420. Ringe J-D (1981) Diagnose und Therapie der Osteoporose. Med Klin 76:129–134PubMedGoogle Scholar
  421. Ringe J-D, Kuhlencordt F (1980) Ostitis fibrosa generalisata. In: Handbuch der Inn Medizin, Bd 6, Teil 18. 5. Auflg. Springer, Berlin Heidelberg New YorkGoogle Scholar
  422. Roberts PAL (1962) Carcinoma of the thyroid, hypoparathyroidism and Cushing’s syndrome. Proc R Soc Med 55:805PubMedGoogle Scholar
  423. Robertson RP, Baylink DJ, Marini JJ, Adkinson HW (1975) Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma. J Clin Endocrinol Metab 41:164PubMedGoogle Scholar
  424. Robertson RP, Baylink DJ, Metz SA, Cummings KB (1976) Plasma prostaglandin E in patients with cancer with and without hypercalcemia. J Clin Endocrinol Metab 43:1330–1335PubMedGoogle Scholar
  425. Roof BS, Carpenter B, Fink DJ, Gorgan GS (1971) Some thoughts on the nature of ectopic parathyroid hormones. Am J Med 50:686PubMedGoogle Scholar
  426. Rosen SW, Becker ChE, Schlaff S, Easton J, Cluck MC (1968) Ectopic gonadotropin production before clinical recognition of bronchogenic carcinoma. N Engl J Med 279:640PubMedGoogle Scholar
  427. Rosenthal FD (1957) Adrenocortical hyperactivity in a patient with bronchial carcinoma and Diabetes mellitus. Br Med J II: 139Google Scholar
  428. Rosenthall L, Kirsh J (1976) Observation of radionuclide imaging in hypertrophic pulmonary osteoarthropathy. Radiology 120:359–362PubMedGoogle Scholar
  429. Ross EJ, Marshall-Jones P, Friedman M (1964) Cushing’s syndrome: Diagnostic criteria. Quart J Med 35:149–192Google Scholar
  430. Roth J (1973) Die paraneoplastischen Syndrome. Systemwirkungen und Indikatoren bösartiger Geschwülste. Hippokrates 44:18–38PubMedGoogle Scholar
  431. Rothmund M (1980) Hyperparathyreoidismus. Thieme, Stuttgart New YorkGoogle Scholar
  432. Rottino A, McGrath JF (1939) Masculinovoblastoma - Primary masculinizing tumor of the ovary (so- called large cell variety - hypernephroid - luteoma). Arch internal Med 63:686–710Google Scholar
  433. Roussel J, Schoumacher P (1956) L’ostéopathie hypertrophiante pneumonique de Pierre-Marie. Sem Hop Paris 32:3037–3038PubMedGoogle Scholar
  434. Rudman D, del Rio A, Akgun S, Frumin E (1969) Novel proteins and peptides in the urine of patients with advanced neoplastic disease. Am J Med 46:174–187PubMedGoogle Scholar
  435. Sachs BA, Becker N, Bloomberg AE, Grunwald RP (1970) “Cure” of ectopic ACTH syndrome secondary to adenocarcinoma of the lung. J Clin Endocrinol Metab 30:590PubMedGoogle Scholar
  436. Saeger W, Mitschke H (1973) Zur Pathologie des Cushing-Syndroms. Dtsch Med Wochenschr 98: 1272–1274PubMedGoogle Scholar
  437. Saint-Paul JP (1938) L’ostéoathopatie hypertrophiante pneumonique de Pierre Marie. Révision du sujet. La périostose engainante acromélique. Thèse de BordauxGoogle Scholar
  438. Samuelson SV, Werner I (1963) Hepatic carcinoma simulating hyperparathyroidism. Acta Med Scand 173:539–547Google Scholar
  439. Samuelsson B, Granström E, Green K, Hamberg M, Hammerström S (1975) Prostaglandins. Annu Rev Biochem 44:669–695PubMedGoogle Scholar
  440. Samuelsson B, Paoletti R (1976) Advances in Prostaglandin and Thrombaxane Research Vol I and II. Raven Press, New YorkGoogle Scholar
  441. Sang Y, Han L, Collins C (1968) Hypertrophic osteoarthropathy in cirrhosis of the liver. Radiology 91:795Google Scholar
  442. Sasano N, Fukuda T, Satoh E (1969) Pathology of ectopic ACTH syndrome with emphasis on pituitary crooke cells and adrenocortical hyperplasia related to ACTH activities in tumor tissues. Tohoku J Exp Med 99:361–380PubMedGoogle Scholar
  443. Schilling F, Knick B, Kuck H (1961) Hyperostosis generalisata mit Cutis verticis gyrata und ihre Differentialdiagnose. Dtsch Arch Klin Med 207:456–491PubMedGoogle Scholar
  444. Schlotthauer CF, Millar JAS (1951) Hypertrophie pulmonary osteoarthropathy in association with pulmonary neoplasms in dogs. J Amer Vet MA 119:442Google Scholar
  445. Schmidt MB (1937) Die sekundäre, hyperplastische Periostitis (P Marie’s Osteoarthropathie hypertrophiante pneumonique, Högler’s Akropachie) In: Lubarsch, Henke, Rössle (Hrsg) Handbuch der Spez pathol Anatomie und Histologie, Bd IX/3 - Knochen und Gelenke. Springer, BerlinGoogle Scholar
  446. Schmidt MC, Lewis AM, Bird ED, Thomas WC (1966) The effect of induced hypercalcemia on the activity of the parathyroid glands. Am J Pathol 48:439–449PubMedGoogle Scholar
  447. Schoenmackers J (1956) Trommelschlegelfinger und -zehen bei angeborenen Herz- und Gefäßfehlern mit Blausucht. Arch Kreislauff 24:363–377Google Scholar
  448. Schubert EH, Vetter R, Juchems R (1970) Pachyder- moperiostose. Münch Med Wochenschr 112:229–235PubMedGoogle Scholar
  449. Schumacher R (1976) Articular manifestations of hypertrophic pulmonary osteoarthropathy in bronchogenic carcinoma. Arthrit Rheum 19:629–636Google Scholar
  450. Seifert G, Junge-Hülsing G (1966) Morphologische Aspekte bei extraossären Verkalkungsvorgängen. In: Hauss WH, Gerlach U (Hrsg) Rheumatismus und Bindegewebe. Steinkopff, DarmstadtGoogle Scholar
  451. Seifert G, Seeman N (1967) Paraneoplastisches Hyper- calcämie-Syndrom bei Ovarialkarzinom. Dtsch Med Wochenschr 92:1104–1107PubMedGoogle Scholar
  452. Seifert G, Riesner K, Schäfer H (1980) Extraossäre Verkalkungen und ektopische Knochenbildung. In: Handbuch Inn Med VI/1 B Klin Osteologie. Springer, Berlin Heidelberg New YorkGoogle Scholar
  453. Selberg W (1941) Beitrag zur Klinik und Pharmakologie der Darmkarzinoide. Klin Wochenschr 20: 1271–1273Google Scholar
  454. Senn HJ, Rhomberg WU, Jungi WF (1971) Störung der leukozytären Abwehrfunktion als paraneoplastisches Syndrom bei Hämoblastosen. Schweiz Med Wochenschr 101:466–470PubMedGoogle Scholar
  455. Senn HJ, Peyer P (1978) Die Therapie des Hypercalcä- miesyndroms bei Tumorpatienten mit besonderer Berücksichtigung von Mithramycin. Dtsch Med Wochenschr 103:101PubMedGoogle Scholar
  456. Seyberth HW (1978) Prostaglandin-mediated hypercalcemia: A paraneoplastic syndrome. Klin Wochenschr 56:373–387PubMedGoogle Scholar
  457. Seyberth HW, Segre GV, Morgan JL, Sweetman BJ, Potts JT jr, Oates JA (1975) Prostaglandins as mediators of hypercalcemia associated with certain types of cancer. N Engl J Med 293:1278PubMedGoogle Scholar
  458. Seyberth HW, Segre GV, Hamet P, Sweetman BJ, Potts JT jr, Oates JA (1976) Characterization of the group of patients with hypercalcemia of cancer who respond to treatment with prostaglandin synthesis inhibitors. Ass Am Physicians 89:92Google Scholar
  459. Seyberth HW, Oelz O, Hough A, Hubbard WC, Raisz LG, Oates JA (1977) Prostaglandins as mediators of hypercalcemia associated with the VX2-carcino- ma in the rabbit. Naunyn Schmiedebergs Arch Pharmacol [Suppl II] 297 : R42Google Scholar
  460. de Séze S, Jourmand SH (1950) Pachydermopérios- tose. Hippocratisme digital chez le père atteint de bronchopneumopathie chronique et chez le frère bien portant. Réflexions sur le rôle du facteur héréditaire et familial dans la genèse des hypertrophies des extrémités. Bull Mém Soc Méd Hôp (Paris) 66:860–864Google Scholar
  461. Shapiro RF, Zvaifler NJ (1973) Concurrent intratho- racic Hodgkin’s disease. Chest 63:912–916PubMedGoogle Scholar
  462. Shaw HB, Cooper RH (1907) Pulmonary hypertrophic osteoarthropathy occurring in a case of congenital heart disease. Lancet 1:880–881Google Scholar
  463. Sherry S, McAllister WH, Saltzstein SL (1963) Cushing’s syndrome associated with a parotid tumor; clinicopathologic conference. Am J Med 34:394Google Scholar
  464. Sherwood LM, Potts JT, Care AD (1966) Evaluation by radioimmunoassay of factors controlling the secretion of parathyroid hormone. Nature 209:52–55PubMedGoogle Scholar
  465. Sherwood LM, O’Riordan JLH, Aurbach GD, Potts JT (1967) Production of parathyroid hormone by nonparathyroid tumors. J Clin Endocrinol Metab 27:140–146PubMedGoogle Scholar
  466. Shiers JA, Neuhauser BD (1957) Idiopathic hypercalcemia. Am J Roentgenol 78:19–29Google Scholar
  467. Silva OL, Becker KL, Primack A, Doppman J, Snider RH (1973) Ectopic production of Calcitonin. Lancet 2:317PubMedGoogle Scholar
  468. Silva OL, Becker KL, Primack A, Doppman J, Snider RH (1974) Ectopic secretion of calcitonin by oatcell carcinoma. N Engl J Med 290:1122PubMedGoogle Scholar
  469. Silva OL, Becker KL, Primack A, Doppman JL, Snider RH (1975) Hypercalcemia in bronchogenic cancer. J Am Med Worn Ass 234:183–185Google Scholar
  470. Singer FR, Powell D, Minkin C (1973) Hypercalcemia in reticulum cell sarcoma without hyperparathyroidism or skeletal metastases. Ann Intern Med 78:365PubMedGoogle Scholar
  471. Singh A, Jolly SS, Bansal BB (1950) Hypertrophic osteoarthropathy associated with carcinoma of the stomach. Br Med J 2:581Google Scholar
  472. Smith LH (1975) Ectopic hormone production. Surg Gynecol Obstet 141:443–453PubMedGoogle Scholar
  473. Snedecor PA, Baker HW (1964) Pseudohyperparathyroidism due to malignant tumors. Cancer 17:1492–1496PubMedGoogle Scholar
  474. Sparagana M, Philips G, Hoffman C, Kucera L (1971) Ectopic growth hormone syndrome associated with lung cancer. Metabolism 20:730PubMedGoogle Scholar
  475. Sprague RG, Hayles AB, Power MH, Mason HL, Bennett WA (1950) “Steroid Diabetes” and alkalosis associated with Cushing’s syndrome. J clin Endocrinol 10:289–306Google Scholar
  476. Sutro CJ, Pomerantz L (1939) Effect of experimentally formed tumors on musculoskeletal system of the rat. Arch Surg 38:1132–1149Google Scholar
  477. Szymendera J (1970) Bone Mineral Metabolism in Cancer. Springer, Berlin Heidelberg New YorkGoogle Scholar
  478. Steckelmacher S (1918) Ein Beitrag zur Kenntnis der hyperplastisch-porotischen Osteoperiostitis (Osteoarthropathie hypertrophiante pneumique (Marie). Dtsch Arch Klin Med 127:242–260Google Scholar
  479. Steel K, Baerg RD, Adams DO (1967) Cushing’s syndrome in association with a carcinoid tumor of the lung. J Clin Endocrinol Metab 27:1285–1289PubMedGoogle Scholar
  480. Steigbigel NH, Oppenheim JJ, Fishman LM, Carbone PP (1964) Metastatic embryonal carcinoma of the testis associated with elevated plasma TSH-like activity and hyperthyroidism. N Engl J Med 271:345PubMedGoogle Scholar
  481. Steiner H, Dahlbäck O, Waldenstrom J (1968) Ectopic growth-hormone production and osteoarthropathy in carcinoma of the bronchus. Lancet 1:783–785PubMedGoogle Scholar
  482. Steinfeld AD, Munzenrider JE (1974) The response of hypertrophic pulmonary osteoarthropathy to radiotherapy. Radiology 113:709–711PubMedGoogle Scholar
  483. Sternberg M (1899) Vegetationsstörungen und Systemerkrankungen der Knochen. In : Nothnagels Handbuch der spez Pathologie und Therapie, Bd VII/2II. Höldner, WienGoogle Scholar
  484. Stewart DM (1928) Hypertrophie osteo-arthropathy. Med Clin North Am 11:1283–1292Google Scholar
  485. Stolbach L, Krant L, Fishman WH (1969) Ectopic production of an alkaline phosphatase isoenzyme in patients with cancer. N Engl J Med 281:757–762PubMedGoogle Scholar
  486. Stone GE, Waterhouse C, Terry R (1961) Hypercalcemia of malignant disease; case report proposed mechanism of etiology. Ann Intern Med 54:977–1202Google Scholar
  487. Stovin PGJ (1965) Syndromes of ectopic hormone production associated with pulmonary neoplasms. Am Rev Respir Dis 92:484–488PubMedGoogle Scholar
  488. Streda A, Padzerka P (1966) Vergleichende röntgenologische und anatomische Untersuchungen der Knochen- und Gelenkssymptome bei der primär chronischen Polyarthritis. Radiologe 6:39Google Scholar
  489. Strott CA, Nugent CA, Tyler FH (1968) Cushing’s syndrome caused by bronchial adenoma. Am J Med 44:97PubMedGoogle Scholar
  490. Studer H, Staub JJ, Wyss F (1971) Klinische und metabolische Fern Wirkungen maligner Tumoren. Schweiz Med Wochenschr 101:446PubMedGoogle Scholar
  491. Tamm J, Kracht J (1965) Akuter Hypercortisolismus bei einer Patientin mit ACTH-bildendem Bronchialcar zinom. Kongr Bericht. Norddtsch Ges Inn Med 64:50Google Scholar
  492. Tashjian AH (1975) Prostaglandins, hypercalcemia and cancer. N Engl J Med 293:1317–1318PubMedGoogle Scholar
  493. Tashjian AH, Levine L, Munson PL (1964) Immunochemical identification of parathyroid hormone in non-parathyroid neoplasms associated with hypercalcemia. J Exp Med 119:467–484PubMedGoogle Scholar
  494. Tashjian AH jr, Voelkel EF, Levine L, Goldhaber P (1972) Evidence that bone resorption stimulating factor produced by mouse fibrosarcoma cells is prostaglandin E2. A new model for the hypercalcemia of cancer. J Exp Med 136:1329–1343PubMedGoogle Scholar
  495. Tashjian AH, Voelkel EF, Goldhaber P (1973) Successful treatment of hypercalcemia by indometha- cin in mice bearing a prostaglandin-producing fibrosarcoma. Prostaglandins 3:515–524PubMedGoogle Scholar
  496. Tashjian AH jr, Tice JE, Sides K (1977) Biological activities of prostaglandin analogues and metabolites on bone in organ culture. Nature 266:645–647PubMedGoogle Scholar
  497. Taylor AN, Wasserman RH (1965) A vitamin D3- dependent factor influencing calcium binding by homogenates of chick intestinal mucosa. Nature 205:248PubMedGoogle Scholar
  498. Taylor DM, Siemsen AW (1965) Bronchogenic carcinoma simulating hyperparathyroidism. Arch Intern Med 115:67–73PubMedGoogle Scholar
  499. Taylor RL, Lynch HJ, Wysor WG (1963) Seasonal influence of sunlight on the hypercalcemia of sarcoidosis. Am J Med 34:221–227PubMedGoogle Scholar
  500. Temple HL, Jaspin G (1948) Hypertrophic osteoarthropathy. Am J Roentgenol 60:232–245Google Scholar
  501. Terry DW jr, Isitman AT, Holmes RA (1975) Radionuclide bone images in hypertrophic pulmonary osteoarthropathy. Am J Roentgenol 124:571–576Google Scholar
  502. Thomas C (1975) Das paraneoplastische Syndrom. Med Klin 70:2053–2065PubMedGoogle Scholar
  503. Thomas C, Zengerling W, Noetzel H (1972) Neurologische Formen des paraneoplastischen Syndroms. Schattauer, Stuttgart New YorkGoogle Scholar
  504. Thomas C, Windt T, Grom E (1974) Hämatologische und endokrine Formen des paraneoplastischen Syndroms. Schattauer, Stuttgart New YorkGoogle Scholar
  505. Thompson JC, Hirose FM, Lemmi CAE, Davidson WD (1972) Zollinger-Ellison syndrome in a patient with multiple carcinoid islet cell tumors of the duodenum. Am J Surg 124:250PubMedGoogle Scholar
  506. Thorburn W, Westmacott FH (1896) Pathology of hypertrophic pulmonary osteoarthropathy. Trans Pathol Soc 47:177–190Google Scholar
  507. Tobler H (1939) Über Ostéoarthropathie hypertrophiante pneumique (Bamberger - Pierre Marie). Diss Univ ZürichGoogle Scholar
  508. Touraine A, Solente, Gole (1935) Un syndrome ostéodermopathique : la pachydermite plicaturée avec pachypériostose des extrémités. Presse Med 43:1820Google Scholar
  509. Trever RW (1958) Hypertrophie osteoarthropathy in association with congenital cyanotic heart disease. Report of two cases. Ann Intern Med 48:660–668PubMedGoogle Scholar
  510. Trivedi SA (1958) Neurolemmoma of the diaphragm causing severe hypertophic pulmonary osteoarthropathy. Br J Dis Chest 52:214Google Scholar
  511. Trousseau A (1877) Clin Méd Hôtel-Dieu Paris 3:94Google Scholar
  512. Turiaf J, Battesti JP, Hardouin JP (1966) Ostéoarthropathie hypertrophiante et diverticule de l’estomac. Pouman Coeur 22:605–612Google Scholar
  513. Turkington RW, Goldman JK, Ruffner WW, Dopson JC (1966) Bronchogenic carcinoma simulating hyperparathyroidism. Cancer 19:406Google Scholar
  514. Turner-Warwick M (1963) Systemic arterial patterns in the lung and clubbing of the fingers. Thorax 18:238PubMedGoogle Scholar
  515. Uehlinger E (1951) Osteopathie hypertrophicans toxica. In: Schinz, Baensch, Friedl, Uehlinger (Hrsg) Lehrbuch der Röntgendiagnostik, Bd I. Thieme, StuttgartGoogle Scholar
  516. Uehlinger E (1964) Hypercalcämie-Syndrome. Münch Med Wochenschr 106:692–701PubMedGoogle Scholar
  517. Uehlinger E (1965) Lungenkarzinom und paraneoplastische Syndrome. Münch Med Wochenschr 107:693–694Google Scholar
  518. Uehlinger E (1966) Paraneoplastische Syndrome. Almanach für Ärztl Fortbildung 6:17–44Google Scholar
  519. Unna PG, Morris M, Duhring LA, Leloir H (1890) Internationaler Atlas seltener Hautkrankheiten, Bd 10. Voss, LeipzigGoogle Scholar
  520. Valenti PF (1955) Die pneumopathische endostale Osteosklerose. Schweiz Z Pathol Bakt 18:143–155Google Scholar
  521. de Vecchis L (1968) Considerazioni sulla osteoartropa- tia ipertrofizzante pneumica die Pierre-Marie Bamberger. Ann Fac Med Perugia 60:39–53Google Scholar
  522. Virchow R (1855) Kalk-Metastasen. Arch Pathol Anat 8:103–113Google Scholar
  523. Voelkel EF, Tashjian AH jr, Franklin R, Wasserman E, Levine L (1975) Hypercalcemia and Tumor- prostaglandins. The VX2 carcinoma model in the rabbit. Metabolism 24:973–986PubMedGoogle Scholar
  524. Vogel MD, Keating FR, Bahn RC (1961) Acute Cushing’s syndrome associated with bronchogenic carcinoma. Proc Staff Meet Mayo Clinic 36:387Google Scholar
  525. Vogl A, Blumenfeld S, Gutner LB (1955) Diagnostic significance of pulmonary hypertrophic osteoarthropathy. Am J Med 18:51–65PubMedGoogle Scholar
  526. Wagner A, Schaaf J (1962) Tuberöse Sklerose der Lunge mit ausgeprägter Ostéoarthropathie hypertrophiante pneumonique. Fortschr Röntgenstr 96:508–514Google Scholar
  527. Wahl AR, Röher H-D (1973) Pseudohyperparathyreoidismus als paraneoplastisches Syndrom bei einem Fall von Magenkarzinom. Dtsch Med Wochenschr 98:565–568PubMedGoogle Scholar
  528. Walser M (1962) The separate effects of hyperparathyroidism hypercalcemia of malignancy, renal failure, and acidosis on the state of calcium, phosphate, and other ions in plasma. J Clin Invest 41:1454PubMedGoogle Scholar
  529. Walser M, Robinson BHB, Duckett JW (1963) The hypercalcemia of adrenal insufficiency. J Clin Invest 42:456–465PubMedGoogle Scholar
  530. Walter RD, Resnick D (1981) Hypertrophic osteoarthropathy of the lower extremity in association with arterial graft sepsis. Amer J Roentgenol 137:1059–1061Google Scholar
  531. Wastie ML, Wong HO, Ang AH (1973) Hypertrophic osteoarthropathy in cyanotic congenital heart disease. Australas Radiol 17:276–279PubMedGoogle Scholar
  532. Weber FP, Ledingham JGC (1909) Über einen Fall von Lymphadenoma (Hodgkin’sche Krankheit) des Mediastinums verbunden mit einer hochgradigen hypertrophischen pulmonalen Osteoarthropathie. Dtsch Arch Klin Med 96:218Google Scholar
  533. Webster GD, Touchstone JC, Suzuki M (1959) Adrenocortical hyperplasia occurring with metastatic carcinoma of the prostate : Report of a case exhibity increased urinary aldosterone and glucocorticoid excretion. J clin Endocrinol 19:967–982Google Scholar
  534. Weens HS, Brown CE (1945) Atrophy of terminal phalanges in clubbing and hypertrophic osteoarthropathy. Radiology 45:27–30Google Scholar
  535. Weinberger M (1921) Osteoarthropathie (Akropachie) bei Lungencarcinom. Wien Arch Inn Med II : 357Google Scholar
  536. Weintraub BD, Rosen SW (1971) Ectopic production of human chorionic somatomammotropin by non trophoblastic cancers. J Clin Endocrinol Metab 32:94PubMedGoogle Scholar
  537. Whalen JP (1974) The resorption of bone and its control : its roentgen significance. Radiology 113:257–266PubMedGoogle Scholar
  538. Whitelaw AGL, Cohen SL (1973) Ectopic production of calcitonin. Lancet 11:442–444Google Scholar
  539. von Wichert P (1967) Skelettveränderungen als paraneoplastisches Syndrom bei Lungentumoren. Dtsch Med Wochenschr 92:2396–2398Google Scholar
  540. von Wichert P (1971) Paraneoplastische Syndrome. Med Klin 66:1461–1465Google Scholar
  541. Wierman WH, Clagett OT, McDonald JR (1954) Articular manifestations in pulmonary diseases. J Am Med Ass 155:1459–1463Google Scholar
  542. Williams BL (1967) Acropachy in a case of thyreotoxicosis. Proc R Soc Med 60:899PubMedGoogle Scholar
  543. Williams ED, Celestin LR (1962) The association of bronchial carcinoid and pluriglandular adenomatosis. Thorax 17:120–127PubMedGoogle Scholar
  544. Williams ED, Brown CL, Doniach I (1966) Pathological and clinical findings in series of 67 cases of medullary carcinoma of thyroid. J Clin Pathol 19:103PubMedGoogle Scholar
  545. Williams ED, Karim SMM, Sandler M (1968) Prostaglandin secretion by medullary carcinoma of the thyroid. Lancet 1:22PubMedGoogle Scholar
  546. Williams ED, Morales AM, Horm RC (1968) Thyroid carcinoma and Cushing’s syndrome. J Clin Pathol 21:129–135PubMedGoogle Scholar
  547. Winand R, Bates R, Becker CE, Rosen SW (1969) Unusual thyroid stimulating activity in the plasma of a man with choriocarcinoma. J Clin Endocrinol Metab 29:1369Google Scholar
  548. Wise HM, Pohl AL, Gazzaniga A, Harrison JH (1965) Hyperadrenocorticism associated with “reactivated” pro static carcinoma. Surgery 57:655–664PubMedGoogle Scholar
  549. Wissing EG, Weisz L (1943) Unusual case of pulmonary osteo-arthropathy in a dog. Am J Roentgenol 50:527–529Google Scholar
  550. Wyss F, Studer H, Staub JJ (1971) Ektopische Hormonbildung. Internist 12:215–219PubMedGoogle Scholar
  551. Yacoub MH (1965) Relation between the histology of bronchial carcinoma and hypertrophic pulmonary osteoarthropathy. Thorax 20:537–539Google Scholar
  552. Yacoub MH, Simon G (1967) Hypertrophic pulmonary osteoarthropathy in association with pulmonary metastases from extrathoracic tumors. Thorax 22:226PubMedGoogle Scholar
  553. Young DM, Fioravanti JL, Prieur DJ, Ward JM (1976) Hypercalcemic VX-2 carcinoma in rabbits - A clinicopathologic study. Lab Invest 35:30–46PubMedGoogle Scholar
  554. Zahnert R (1956) Das Krankheitsbild der Ostéoarthropathie hypertrophiante pneumonique (Bam- berger-Pierre Marie). Dtsch Ges-Wesen 10:1774–1778Google Scholar
  555. Zeschkowski MS, Solowjow JN, Tarassow BP (1970) Röntgenmorphologische Untersuchungen über Knochenneubildung bei malignen Tumoren des Skeletts. Radiol Diagn (Berl) 11:61–70Google Scholar
  556. Ziegler R, Minne H, Bellwinkel S, Fröhlich D (1973) Hypercalcämie-Syndrom und hyperkalzämische Krise. Symptomatik, Differentialdiagnose und Therapie. Dtsch Med Wochenschr 98:276–283PubMedGoogle Scholar
  557. Zornoza J, Cangir A, Green B (1977) Hypertrophie osteoarthropathy associated with nasopharyngeal carcinoma. Am J Roentgenol 128:679–681Google Scholar

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© Springer-Verlag Berlin · Heidelberg 1983

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  • F. Heuck

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