Biogene Amine im menschlichen Prostatagewebe

  • K. Van Camp
Conference paper
Part of the Verhandlungsbericht der Deutschen Gesellschaft für Urologie book series (VBDGUROLOGIE, volume 32)

Zusammenfassung

Die Bestimmung der Polyamine in Harn, Serum, Plasma ist ein wertvoller Maßstab für die Diagnostik metastasierter Karzinome und für das Verfolgen einer eingestellten Behandlung [1, 2,4, 5,6, 7,8,9,13,14,15,16,17]. Man kann ja eindeutig zeigen, daß bei schnellem Wachstum oder bei Zelldestruktion die Polyaminsynthese sich steigert, was sich äußert in der Polyamin- Konzentration biologischer Flüssigkeiten.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Chaisiri P, Harper ME, Griffiths K (1979) Plasma spermine concentrations of patients with benign and malignant tumours of the breast or prostate. Clin Chim Acta 92:273–282.PubMedCrossRefGoogle Scholar
  2. 2.
    Chaisiri P, Harper ME, Blarney RW, Peeling WB, Griffiths K (1980) Plasma spermidine concentrations in patients with tumours of the breast or testis. Clin Chim Acta 104:367–375.PubMedCrossRefGoogle Scholar
  3. 3.
    Dierick NA, Vervaeke IJ, de Cuypere JA, Henderickx HK (1976) Determination of biogenic amines in intestinal contents by ion-exchange chromatography. J Chromat 129:403–406.CrossRefGoogle Scholar
  4. 4.
    Durie BGM, Salmon SE, Russell DH (1977) Polyamines as markers of response and disease activity in cancer chemotherapy. Cancer Res 37:214–221.PubMedGoogle Scholar
  5. 5.
    Dreyfuss F, Chayen R, Dreyfuss G, Divir R, Ratan J (1975) Poly amine excretion in the urine of cancer patients. Israel J Med Sci 11:785–795.PubMedGoogle Scholar
  6. 6.
    Dunzendorfer U, Russell DH (1978) Altered poly amine profiles in prostatic hyperplasia and in kidney tumors. Cancer Res 38:2321–2324.PubMedGoogle Scholar
  7. 7.
    Fair WR, Wehner N, Brorsson U (1975) Urinary polyamine levels in the diagnosis of carcinoma of the prostate. J Urol 114:88–92.PubMedGoogle Scholar
  8. 8.
    Lipton A, Sheeman L, Motel R, Harvey HA (1976) Urinary polyamine levels in patients with localized malignancy. Cancer 38:1344–1347.PubMedCrossRefGoogle Scholar
  9. 9.
    Marton LJ, Heby O, Wilson CB, Lee PLY (1974) A method for the determination of polyamines in cerebrospinal fluid. FEBS Letters 46:305–307.PubMedCrossRefGoogle Scholar
  10. 10.
    Marton LJ, Russell DH, Levy CC (1973) Measurement of putrescine spermidine and spermine in physiological fluids by use of an amino acid analyzer. Chin Chem 19:923–926.Google Scholar
  11. 11.
    Morris DR, Koffron KL, Okstein CJ (1969) An automated method for polyamine analysis. Anal Biochem 30:449–451.PubMedCrossRefGoogle Scholar
  12. 12.
    Nishioka K, Romsdahl MM (1974) Elevation of putrescine and spermidine in sera of serum polyamines in patients with solid tumours. Clin Chim Acta 57:155–161.PubMedCrossRefGoogle Scholar
  13. 13.
    Russell DH (1971) Increased polyamine concentration in the urine of human cancer patients. Nature 233:144–145.Google Scholar
  14. 14.
    Russell DH, Levy CC, Schimpff SC, Hanke JA (1971) Urinary polyamines in cancer patients. Cancer Res 31:1555–1558.PubMedGoogle Scholar
  15. 15.
    Russell DH, Russell SD (1975) Relative usefulness of measuring polyamines in serum, plasma and urine as biochemical markers of cancer. Chin Chem 21:860–863.Google Scholar
  16. 16.
    Sanford EJ, Drago JR, Rohner IJ, Kessler GE, Sheenan L, Lipton A (1975) Preliminary evaluation of urinary polyamines in the diagnosis of genitourinary tract malignancy. J Urol 113:218–221.PubMedGoogle Scholar
  17. 17.
    Waalkes TP, Gehrke CW, Tormey DS, Zumwalt RW, Heuser JN, Lakings DB, Ahman DZ, Moertel CG (1975) Urinary excretion of polyamines by patients with advanced malignancy. Cancer Chemotherapy Rept 59:1103–1116Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg New York 1981

Authors and Affiliations

  • K. Van Camp
    • 1
  1. 1.Universitaire Instelling AntwerpenWilrijkBelgium

Personalised recommendations