Abstract
We propose to consider radiotherapy as adjuvant when the two following conditions are present: (1) The tumor is not palpable or not visible, therefore the target-volume is a subclinical disease; and (2) the dose delivered to this infraclinical cancer is never higher than 50 Gy (5,000 rad) with the classical time-dose relationship five sessions per week (10 Gy, or 1,000 rad, per week). In some circumstances the dose can be lower than 50 Gy: when the tumor is very radiosensitive (i.e., testicular seminoma); when the tolerance of critical organs forces a decrease of the delivered dose (i.e., 20 Gy in front of the kidneys for ovarian cancer); and when the dose is delivered with a nonconventional fractionation (i.e., 30 Gy in 2 weeks).
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Chassagne, D. (1982). Radiotherapy as Adjuvant Local Therapy of Local Tumors. In: Mathé, G., Bonadonna, G., Salmon, S. (eds) Adjuvant Therapies of Cancer. Recent Results in Cancer Research, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81685-7_4
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DOI: https://doi.org/10.1007/978-3-642-81685-7_4
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