Malnutrition in Lung Cancer: Incidence, Prognostic Implications, and Pathogenesis

  • D. L. Kisner
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 80)


Malnutrition and weight loss are common in patients with lung cancer. Weight loss is an independent prognostic factor for survival in lung cancer treatment studies. Metabolic disturbances probably play a dominant role in weight loss in these patients rather than reduced food intake. The identification of the pertinent etiologic metabolic abnormalities and development of specific therapeutic intervention should be goals for future research.


Lung Cancer Patient Reduce Food Intake Specific Therapeutic Intervention Weight Loser Inoperable Lung Cancer 
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  1. 1.
    Brennan M (1977) Uncomplicated starvation versus cancer cachexia. Cancer Res 37:2359–2364PubMedGoogle Scholar
  2. 2.
    Costa G, Bewley P, Aragón M, Siebold J (to be published) Anorexia and weight loss in cancer patients. Cancer Treat RepGoogle Scholar
  3. 3.
    DeWys W, Begg C, Lavin P, et al. (to be published) Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J MedGoogle Scholar
  4. 4.
    Issel B, Valdivieso M, Bodey G (1978) Chemotherapy for adenocarcinoma and large cell anaplastic carcinoma of the lung with ftorafur, adriamycin and cis-dichloro- diammineplatinum (II). Cancer Treat Rep 62:1089–1091Google Scholar
  5. 5.
    Issel B, Valdivieso M, Hersch E, Richman S, Gutterman J, Bodey G (1978) Combination chemoimmunotherapy of extensive non-oat cell lung cancer. Cancer Treat Rep 62:1059–1063Google Scholar
  6. 6.
    Issel B, Valdivieso M, Zaren H, Dudrick S, Freireich E, Copeland E, Bodey G (1978) Protection against chemotherapy toxicity by intravenous hyperalimentation. Cancer Treat Rep 62:1139–1143Google Scholar
  7. 7.
    Kisner D, DeWys W (to be published) Anorexia and cachexia in malignancy. In: Newell G, Ellison N (eds) Cancer and nutrition. Raven Press, New YorkGoogle Scholar
  8. 8.
    Lanzotti V, Thomas D, Boyle L, Smith T, Gehan E, Samuels M (1977) Survival with inoperable lung cancer. Cancer 39:303–313PubMedCrossRefGoogle Scholar
  9. 9.
    Warnold I, Lundholm K, Schersten T (1978) Energy balance and body composition in cancer patients. Cancer Res 38:1801–1807PubMedGoogle Scholar
  10. 10.
    Warren S (1932) The immediate causes of death in cancer. Am J Med Sci 184:610–615CrossRefGoogle Scholar
  11. 11.
    Zelen M (1973) Keynote address on biostatistics and data retrieval. Cancer Chemother Rep 4:31–42Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1982

Authors and Affiliations

  • D. L. Kisner
    • 1
  1. 1.Division of Cancer Treatment, Cancer Therapy Evaluation ProgramNational Cancer InstituteBethesdaUSA

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