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Metastatic CNS Disease in Small Cell Carcinoma of the Bronchus: The Role of Radiotherapy and Chemotherapy

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Adjuvant Therapies of Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 80))

Abstract

Improved survival frequently reveals new patterns in malignant disease. Control of central nervous system (CNS) disease in acute lymphoblastic leukaemia (ALL) is responsible for the profound improvement in prognosis for that disease [32] and is a stimulus to examine yet more closely specific features of the natural history of other cancers. Small cell cancer of the lung (SCBC) has some similarity to ALL: It is sensitive to some anticancer drugs; it is often widely disseminated; and without treatment it is rapidly fatal, and spreading to the CNS is now recognised to occur in a significant proportion of cases. Although only representing about 25% of lung cancers, it is of particular interest because of these characteristics.

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Authors and Affiliations

  1. Wessex Regional Medical Oncology Unit, CRC, Southampton, UK

    J. M. A. Whitehouse & C. J. Williams

Authors
  1. J. M. A. Whitehouse
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  2. C. J. Williams
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Editor information

Editors and Affiliations

  1. Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, 14-16 Avenue Paul-Vaillant-Couturier, F-94800, Villejuif, France

    G. Mathé

  2. Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, I-20133, Milan, Italy

    G. Bonadonna

  3. Health Science Center Department of Internal Medicine Section of Hematology and Oncology Tucson, The University of Arizona, 85724, AZ, USA

    S. Salmon

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© 1982 Springer-Verlag Berlin · Heidelberg

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Whitehouse, J.M.A., Williams, C.J. (1982). Metastatic CNS Disease in Small Cell Carcinoma of the Bronchus: The Role of Radiotherapy and Chemotherapy. In: Mathé, G., Bonadonna, G., Salmon, S. (eds) Adjuvant Therapies of Cancer. Recent Results in Cancer Research, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81685-7_33

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  • DOI: https://doi.org/10.1007/978-3-642-81685-7_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81687-1

  • Online ISBN: 978-3-642-81685-7

  • eBook Packages: Springer Book Archive

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