Summary
The Cancer and Leukemia Group B (CALB) has conducted a randomized study of adjuvant chemotherapy in patients with breast cancer who have involved axillary nodes at the time of mastectomy. Five-drug treatment (CMFVP) was compared with three-drug treatment (CMF). For patients with more than three involved nodes, the CMFVP regimen produced a significantly prolonged disease-free survival in comparison to the CMF regimen.
This work was supported by grants CA 04457 and CA 16118 from the Division of Cancer Treatment, National Cancer Institute, Bethesda, MD (USA)
The authors thank Mrs. Barbara B. Shepherd for her valuable assistance in the preparation of this manuscript
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© 1982 Springer-Verlag Berlin · Heidelberg
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Weiss, R.B. et al. (1982). A Randomized Trial of Postoperative Five-Versus Three-Drug Chemotherapy After Mastectomy: A Cancer and Leukemia Group B (CALGB) Study. In: Mathé, G., Bonadonna, G., Salmon, S. (eds) Adjuvant Therapies of Cancer. Recent Results in Cancer Research, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81685-7_28
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DOI: https://doi.org/10.1007/978-3-642-81685-7_28
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