Skip to main content

Role of Lung Irradiation in the Adjuvant Treatment of Osteosarcoma

  • Chapter

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 80))

Abstract

The vast majority of osteogenic sarcoma originates in bones of the limbs, and radical surgery can nearly always control the primary tumor. The prognosis of these patients is thus determined by the appearance of distant metastases, mainly in the lungs. The results of treatment of overt metastases are very limited, though the last decade has seen a great effort to improve therapeutic results by eliminating tumor deposits when they are not yet detectable, thus containing smaller numbers of tumor cells.

For the Cooperative Radiotherapy-Chemotherapy Group of the EORTC

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Abbatucci JS, Boulier A, Fabre J, Lozier JC (1979) Functional evaluation of pulmonary irradiation effects. Eur J Cancer 14:781–785

    Google Scholar 

  2. Breur K, van der Schueren E (1979) Adjuvant therapy in the management of osteosarcoma: Need for critical reassessment. Recent Results Cancer Res 68:5–15

    Article  Google Scholar 

  3. Breur K, Cohen P, Schweisguth O, Hart AMM (1978) Irradiation of the lungs as an adjuvant therapy in the treatment of osteosarcoma of the limbs. Eur J Cancer 14:461–471

    Article  PubMed  CAS  Google Scholar 

  4. Cohen P (1979) Osteosarcoma of the long bones. Eur J Cancer 14:995–1004

    Google Scholar 

  5. Edmonson JH, Green SJ, Ivins JC, Gilchrist GS, Creagan ET, Burgert EO, Pritchard DJ, Hahn RG, Dahlin DC, Taylor WF (1980) Post-surgical treatment of primary osteosarcoma of bone-comparison of high dose methotrexate vs. observation: Preliminary report. Proc Am Soc Clin Oncol 620:476

    Google Scholar 

  6. Gehan EA, Sutow WW, Uribe-Botero G, Romsdahl M, Smith TL (1978) Osteosarcoma: The M.D. Anderson experience, 1950–1974. In: Terry WD, Windhorst D (eds) Immunotherapy of cancer: Present status of trials in man. Raven Press, New York, pp 271–282

    Google Scholar 

  7. Jeffree GM, Price DHG, Sissons HA (1975) The metastatic patterns of osteosarcoma. Br J Cancer 32: 87–107

    Article  PubMed  CAS  Google Scholar 

  8. Marcove RC, Miké V, Hajek JV, Levin AC, Hutter RVP (1970) Osteogenic sarcoma under the age of 21. J Bone Joint Surg [Am] 52:411–423

    CAS  Google Scholar 

  9. Pratt CB (1980) Chemotherapy of osteosarcoma: An overview. In: Van Oosterom AT, Muggia FM, Cleton FJ (eds) Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas, vol 16. Leiden University Press, Leiden (Boerhaave Series, pp 329–348)

    Chapter  Google Scholar 

  10. Rab GT, Ivins JC, Childs DS Jr, Cupps RE, Pritchard DJ (1976) Elective whole lung irradiation in the treatment of osteogenic sarcoma. Cancer 38:939–942

    Article  PubMed  CAS  Google Scholar 

  11. Rosen G, Marcove RC, Caparros B, Nirenberg A, Kosloff C, Huvos AG (1979) Primary osteogenic sarcoma. The rationale for preoperative chemotherapy and delayed surgery. Cancer 43:2163–2177

    Article  PubMed  CAS  Google Scholar 

  12. Rosen G, Caparros B, Nirenberg A, Juergens H, Huvos AG (1980) The successful management of metastatic osteogenic sarcoma: A model for the treatment of primary osteogenic sarcoma. In: Van Oosterom AT, Muggia FM, Cleton FJ (eds) Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas, vol 16. Leiden University Press, Leiden (Boerhaave Series, pp 349–366)

    Chapter  Google Scholar 

  13. Rosenberg SA, Sindelar WF (1980) Surgery and adjuvant chemo-immunotherapy in osteosarcoma: Review on treatment at the National Cancer Institute. In: Van Oosterom AT, Muggia FM, Cleton FJ (eds) Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas, vol 16. Leiden University Press, Leiden (Boerhaave Series, pp 301–316)

    Chapter  Google Scholar 

  14. Taylor WF, Inis JC, Dahlin DC, Pritchard DJ (1978) Osteogenic sagoma experience at the Mayo Clinic, 1963–1974. In: Terry WD, Windhorst D (eds) Immunotherapy of cancer: Present status of trials in man. Raven Press, New York, pp 257—269

    Google Scholar 

  15. Van der Schueren E, Breur K, Schweisguth O, Voute PA, Cohen P, Machin D (1979) Assessment of the role of chemotherapy and radiotherapy as adjuvant in the treatment of osteosarcomas of the limbs. A trial of the EORTC (Clinical Group Radiotherapy/Chemotherapy) and of the SIOP. Eur J Cancer 15:1001–1003

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

van der Schueren, E., Breur, K. (1982). Role of Lung Irradiation in the Adjuvant Treatment of Osteosarcoma. In: Mathé, G., Bonadonna, G., Salmon, S. (eds) Adjuvant Therapies of Cancer. Recent Results in Cancer Research, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81685-7_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-81685-7_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81687-1

  • Online ISBN: 978-3-642-81685-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics