Detergent Scrub Method: A Useful Assay for Control of Antidandruff Preparations
The detergent scrub is an established method for the investigation of cutaneous microflora (Williamson and Kligman 1965). The scrub sample allows quantitation of the bacterial microflora and direct cell counts of Pityrosporum yeasts. Furthermore this method is suitable in studying scaling diseases as the desquamating portion of the horny layer is removed (McGinley et al. 1969, Plewig and Kligman 1969). Severity of dandruff is directly proportional to the corneocyte count (McGinley et al. 1969).
KeywordsSalicylic Acid Stratum Corneum Glass Cylinder Quantitative Culture Horny Layer
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