Hair Research pp 169-171 | Cite as

Hair Follicles and Their Environment

  • G. Moretti
  • P. Cardo
  • V. Moreno
Conference paper

Abstract

An understanding of the relationship between epidermis and dermis is probably the key to events in the normal and pathologic life of hair follicles. The ectodermal parts of the follicle are so closely and firmly attached to the mesodermal parts by way of the connective sheath and dermal papilla that a strong pull is needed to pluck a hair still attached to its papilla (Ludwig, 1969). Changes in the relative positions, sizes and shapes of the two elements are prerequisite to changes in follicular structure; thickening and wrinkling of the connective tissue sheath and of the glassy membrane are simultaneous with the beginning of catagen, i.e., with the formation of a club hair, the involution of the outer ectodermal sheath and the escape of the dermal papilla from its refuge in the bulbar cavity, all marks of the end of anagen. Conversely, the reentry of a papilla into the bulb always coincides with the beginning of anagen (Montagna and Parakkal, 1974; Kligman, 1959).

Keywords

Polysaccharide Shrinkage Testosterone Sulfated Acid Methotrexate 

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References

  1. Burgio GR, Nespoli L (1974) Ageing, T lymphocytes, and Down’s syndrome. Lancet II: 1580Google Scholar
  2. Cohen J (1969) Dermis, epidermis and dermal papillae interacting. In: Montagna W, Dobson RL (eds) Advances in biology of skin, Vol 9, Hair growth. Pergamon, Oxford, pp 1–17Google Scholar
  3. Crovato F, Moretti G, Bertamino R (1973) 17-beta-hydroxysteroiddehydrogenases in hair follicles of normal and bald scalp: A histochemical study. J Invest Dermatol 60:126PubMedCrossRefGoogle Scholar
  4. Daman AL, Rosemberg WE, Drake L (1978) Treatment of alopecia areata with dinitrochlorobenzene. Arch Dermatol 114:1036PubMedCrossRefGoogle Scholar
  5. Durward A, Rudall KM (1958) The vascularity and pattern of growth of hair follicles. In: Montagna W, Ellis RA (eds) Biology of hair growth. Academic, New York, pp 189–217Google Scholar
  6. Ellis RA, Moretti G (1959) Vascular patterns associated with catagen hair follicles in the human scalp. Ann NY Acad Sci 83:448PubMedCrossRefGoogle Scholar
  7. Giacometti L, Montagna W (1968) The nerve fibers in male pattern alopecia. In: Baccaredda-Boy A, Moretti G, Frey JR (eds) Biopathology of pattern alopecia. Karger, Basel New York, pp 208–215Google Scholar
  8. Kligman AM (1959) The human hair cycle. J Invest Dermatol 33:307PubMedCrossRefGoogle Scholar
  9. Lillie FR, Wang H (1943) Physiology and development of the feather. VI. The production and analysis of feather-chimerae in the fowl. Physiol Zool 16:1Google Scholar
  10. Lillie FR, Wang H (1944) Physiology and development of the feather. VII. An experimental study of induction. Physiol Zool 17:1Google Scholar
  11. Ludwig E (1969) Separation of the hair from its papilla and connective tissue sheath in plucked anagen hairs. In: Montagna W, Dobson RL (eds) Advances in biology of skin, vol. 9, Hair growth. Pergamon, Oxford, pp 177–182Google Scholar
  12. Lux SE, Johnston RB Jr, August CS, Say B, Pencharzadet VB, Rosen FS, McCusick VA (1970) Chronic neutropenia and abnormal cellular immunity in cartilage-hair hypoplasia. N Engl J Med 282:231PubMedCrossRefGoogle Scholar
  13. Montagna W, Chase HB, Malone JD, Melaragno HP (1952) Cyclic changes in polysaccharides of the papilla of the hair follicle. Q J Micr Sci 93:241Google Scholar
  14. Montagna W, Parakkal PF (1974) The pilary apparatus. In: Montagna W, Parakkal PF (eds) The structure and function of skin. Academic, New York, pp 172–251Google Scholar
  15. Moretti G (1965) Das Haar. In: Stüttgen G (ed) Die normale und pathologische Physiologie der Haut. Fischer, Stuttgart, pp 506–553Google Scholar
  16. Moretti G, Rebora A, Rampini E (1963) Il volume della ghiandola sebacea nell’alopecia areata. Minerva Dermatologica 38:246Google Scholar
  17. Mulay S, Finkelberg R, Pinky L, Solomon S (1972) 4–14C testosterone by serially subcultured human skin fibroblasts. J Clin Endocrinol 34:133CrossRefGoogle Scholar
  18. Oliver RF (1967) Ectopic regeneration of whiskers in the hooded rat from implanted length of vibrissa follicle wall. J Embryol Exp Morphol 17:27PubMedGoogle Scholar
  19. Oliver RF (1969) Regeneration of the dermal papilla and its influence on whisker growth. In: Montagna W, Dobson RL (eds) Advances in biology of skin, vol. 9, Hair growth. Pergamon, Oxford, pp 19–32Google Scholar
  20. Pantelouris EM (1968) Absence of thymus in a mouse mutant. Nature 217:370PubMedCrossRefGoogle Scholar
  21. Parnell JP (1949) Postnatal development and functional histology of the sebaceous glands in the rat. Am J Anat 85:41PubMedCrossRefGoogle Scholar
  22. Rampini E, Bertamino R, Moretti G (1968) Size and shape of sebaceous glands in male pattern alopecia. In: Baccaredda-Boy A, Moretti G, Frey JR (eds) Biopathology of pattern alopecia. Karger, Basel New York, pp 155–165Google Scholar
  23. Rampini E, Moretti G (1973) Cutaneous metabolism of estradiol and testosterone in the newborn rat till puberty. Minerva Dermatologica 108:49Google Scholar
  24. Rampini E, Moretti G, Rebora A (1963) Arteriole e capillari della cute ed alopecia areata. Minerva Dermatologica 38:290Google Scholar
  25. Shames DD, Hirchorn K, New MI (1972) Metabolism of testosterone–14C by culture of human cell. J Clin Invest 51:1499Google Scholar
  26. Van Scott EJ (1958) Response of hair roots to chemical and physical influence. In: Montagna W, Ellis RA (eds) The biology of hair growth. Academic, New York, pp 441–449Google Scholar
  27. Van Scott EJ, Ekel TM (1958) Geometric relationship between the matrix of the hair bulb and its dermal papilla in normal and alopecie scalp. J Invest Dermatol 31:281Google Scholar
  28. Van Scott EJ, Ekel TM, Auerbach R (1963) Determinants of rate and kinetics of cell division in scalp hair. J Invest Dermatol 41:269Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • G. Moretti
    • 1
  • P. Cardo
    • 1
  • V. Moreno
    • 1
  1. 1.Clinica DermatologicaUniversitá di GenovaItaly

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