Abstract
The retinae of anaesthetised Dutch rabbits were exposed to light of various known intensities for one hour. Immediately after exposure the animals were killed and retinal and choroidal tissues were taken for investigation by electron microscopy from selected sites within the previously illuminated area.
Initial qualitative observations suggested that a considerable variation in the degree of cellular damage had occurred even within retinal and choroidal tissues taken from the same eye.
This variability of damage appeared to be related to intensity of illumination and patency of the choroidal vasculature. The mechanisms which could be underlying this variation of damage and possible methods of quantification are discussed.
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Basinger S, Hoffman N, Matthes M (1976) Photoreceptor shedding is initiated by light in the frog retina. Science 194:1074
Besharse JC, Hollyfield JG, Rayborn ME (1977) Turnover of rod photoreceptor outer segments: membrane addition and loss in relationship to light. J Cell Biol 75:507
Bunt AH (1978) Fine structure and radio-autography of rabbit photoreceptor cells. Invest Ophthal 17:90–104
Friedmann E, Kuwabara T (1968) The retinal pigment epithelium IV. The damaging effects of radiant energy. Arch Ophthalmol 80:265–279
Fuller D, Machemer R, Knighton RW (1978) Retinal damage produced by intraocular fibre optic light. Am J Ophthalmol 85(4): 519–537
Gorn RA, Kuwabara T (1967) Retinal damage by visible light: A physiologic study. Arch Ophthalmol 77: 115–118
Grignolo A, Orgalesi N, Castellazzo R, Vitone P (1969) Retinal damage by visible light in albino rats. An electron microscope study. Ophthalmologica 157: 43–59
Hansson HA (1970) A histochemical study of oxidative enzymes in rat retina damaged by visible light. Exp Eye Res 9:285–296
Hansson HA (1970) Ultrastructural studies on rat retina damaged by visible light. Virchows Archiv (Cell Pathol) 6:247–262
Hansson HA (1971) A histochemical study of cellular reactions in rat retina transiently damaged by visible light. Exp Eye Res 12:270–274
Hochheimer BF, D’Anna SA, Calkins JL (1977) Retinal damage from light. Am J Ophthalmol 88:1039–1044
Hollyfield JG, Besharse JC, Rayborn ME (1976) The effect of light on the quantity of phagosomes in the pigment epithelium. Exp Eye Res 23:623–635
Hughes A (1972) A schematic eye for the rabbit. Vision Res 12: 123–138
Kuwabara T, Gorn RA (1968) Retinal damage by visible light: An electron microscopic study. Arch Ophthalmol 79:69–78
LaVail MM (1976) Rod outer segment disc shedding in relation to cyclic lighting. Exp Eye Res 23:277–280
McKechnie NM, Foulds WS (1978) Some aspects of radiant energy damage to the retina. Albrecht v. Graefes Arch klin exp Ophthal 208: 109–124
Noel WK, Walker VS, Kang BS, Berman S (1966) Retinal damage by light in rats. Invest Ophthal 5: 450–473
Noel WK, Albrecht R (1971) Irreversible effects of visible light on the retina: Role of Vitamin A. Science 172:76–80
O’Steen WK, Shear CR, Anderson KV (1972) Retinal damage after prolonged exposure to visible light: A light and electron microscope study. Am J Anat 134: 5–22
Sjostrand FS, Nilsson SE (1964) In: The rabbit in eye research. (JH Prince, ed), Thomas, Springfield, Illinois
Weibel ER (1969) Stereological principles for morphemetry in electron microscopic cytology. Int Rev Cytol 26: 235–302
Young RW (1978) The daily rhythm of shedding and degradation of rod and cone outer segment membrane in the chick retina. Invest Ophth Visual Sci 17: 105–116
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© 1981 Springer-Verlag Berlin · Heidelberg
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McKechnie, N.M., Foulds, W.S. (1981). Qualitative Observations on the Variation of Light Induced Damage to the Rabbit Retina. In: Lee, W.R. (eds) Transactions of the 8th Annual Meeting of the European Club for Ophthalmic Fine Structure in West Berlin, Maren 28 and 29,1980. Current Research in Ophthalmic Electron Microscopy, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81614-7_10
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DOI: https://doi.org/10.1007/978-3-642-81614-7_10
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