Hirsutism of Ovarian Origin
Polycystic ovarian syndrome was first described by Stein and Leventhal (1935) as an anovulatory syndrome with menstrual cycle disorders, sterility, virilization and increased size of the ovaries. These clinical and anatomical features were quickly found to be an insufficient description, and many authors tried to elucidate the physiopathology of this syndrome, the main question being: Is this syndrome of hypothalamopituitary or ovarian origin? Methodological progress in hormonology, especially radioimmunoassays and dynamic stimulation tests, now allows a better understanding of the mechanism, and even though these tests do not assure the causal lesion, they provide a good definition of the characteristic features of this syndrome at both the hypothalamopituitary and ovarian levels.
KeywordsGranulosa Cell Ovarian Tumour Leydig Cell Polycystic Ovary Polycystic Ovarian Syndrome
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