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Modellstudie zur Hämopoetischen Stammzellregulation — Ergebnisse und Probleme

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Modelle in der Medizin

Part of the book series: Medizinische Informatik und Statistik ((MEDINFO,volume 22))

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Zusammenfassung

Das hämopoetische System gliedert sich in eine Reihe morphologisch und funktionell zu unterscheidende Compartments. Die morphologisch nicht eindeutig identifizierten Knochenmarkstammzellen bilden dabei einen sich selbst reproduzierenden Zellpool, aus dem sich über verschiedene Differenzierungs-, Teilungs- und Reifungsstufen die Blutzellen (Erythrozyten, Thrombozyten und Leukozyten) entwickeln. Die Anzahl dieser Funk-tionszellen regelt über ein oder mehrere Hormone die Proliferation der Vorstufen. In Abb. 1 ist dieser Regelkreis für eines der drei Zellsy-steme dargestellt.

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Authors and Affiliations

  1. Medizinische Universitätsklinik, Köln, Deutschland

    M. Löffler & H. E. Wichmann

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  1. M. Löffler
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  2. H. E. Wichmann
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Editors and Affiliations

  1. Institut für medizinische Statistik und Biomathematik der medizinischen Einrichtungen, Universität Düsseldorf, Moorenstraße 5, 4000, Düsseldorf, Deutschland

    H.-J. Jesdinsky

  2. Institut für medizinischen Dokumentation und Statistik, Universität zu Köln — IMDS —, Joseph-Stelzmann-Straße 9, 5000, Köln 41, Deutschland

    V. Weidtman

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© 1980 Springer-Verlag Berlin · Heidelberg

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Löffler, M., Wichmann, H.E. (1980). Modellstudie zur Hämopoetischen Stammzellregulation — Ergebnisse und Probleme. In: Anderson, J., et al. Modelle in der Medizin. Medizinische Informatik und Statistik, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81512-6_31

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  • DOI: https://doi.org/10.1007/978-3-642-81512-6_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10255-7

  • Online ISBN: 978-3-642-81512-6

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