Abstract
It is well established that the hormonal milieu of the patient significantly influences the growth rates of certain breast tumors. Clinical observations since the turn of the century indicate that 25%–40% of breast cancers respond to the surgical removal of hormone-producing glands such as the ovaries in the premenopausal woman or the adrenals in the postmenopausal patient. Administration of pharmacologic doses of estrogens and androgens also may bring about breast tumor remissions.
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Wittliff, J.L., Fisher, B., Durant, J.R. (1980). Establishment of Uniformity in Steroid Receptor Analyses Used in Cooperative Clinical Trials of Breast Cancer Treatment. In: Henningsen, B., Linder, F., Steichele, C. (eds) Endocrine Treatment of Breast Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81406-8_30
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DOI: https://doi.org/10.1007/978-3-642-81406-8_30
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