Lack of Estrogen Receptor Associated with an Increased Response Rate to Cytotoxic Chemotherapy in Metastatic Breast Cancer?
Recent advances in the management of metastatic breast cancer have led to a significant improvement in patient care. A variety of new kinds of endocrine therapy, such as antiestrogen administration or medical adrenalectomy with aminoglutethimide, have reduced the toxicity of endocrine therapy. The use of steroid receptor determinations has improved the selection of patients for endocrine therapy enormously, such that about 75% accuracy in patient assignment for or against endocrine therapy can be anticipated.
KeywordsEstrogen Receptor Endocrine Therapy Metastatic Breast Cancer Cytotoxic Chemotherapy Amino Glutethimide
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