The Significance of Tumour “Stimulation” by Tamoxifen

  • B. A. Stoll
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 71)

Abstract

Several publications on tamoxifen therapy in advanced breast cancer have reported a “flare” in the tumour soon after the onset of therapy. Although it is said to occur in about 10% of cases, it leads to withdrawal of patients from tamoxifen therapy in less than 0.5% of treated patients (Patterson and Baum, 1978). In this brief presentation, I would like to consider three questions: What is this flare? What does it indicate? Is it safe to continue tamoxifen therapy when it occurs?

Keywords

Corticosteroid Flare Prostaglandin Tamoxifen Prednisolone 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • B. A. Stoll
    • 1
  1. 1.Department OncologySt. Thomas’ HospitalLondonSE1 7EHUK

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