Activity of a Rat Uterus Proteinase Inhibitor During Pregnancy and Involution Its Possible Importance in Control of Proteolysis in the Myometrium
The weight of the rat uterus, like that of other mammals, increases several-fold during gestation, which in the rat lasts 21 days, and the highest rate of growth occurs in the last third of this period (Fig.1). The major portion of this increase in weight is due to the growth of the muscle layer of the uterus, the myometrium. Conversely, immediately after delivery there is a dramatic involution of the uterus, and in the rat the nonpregnant uterine weight is reached within four days (1).
KeywordsHydrolysis Filtration Estrogen Titration Cysteine
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- 5.Pennington RT (1977) Proteinases of muscle. In: Barrett AJ (ed) Proteinases in mammalian cells and tissues. North Holland Publishing Co, New York p 515–543Google Scholar
- 15.Roth M, Becker ML, Afting EG (1976) Actomyosin degrading activities in myometri¬um of rat and pig. Hoppe Seylers Z Physiol Chem 357: 277Google Scholar
- 19.Heimburger N (1975) Proteinase inhibitors of human plasma, their properties and control functions. In: Reich E, Rifkin DB, Shaw E (eds) Proteases and biological control. Cold Spring Harbor Lab, p 367–386Google Scholar
- 20.Fritz H, Tschesche H, Greene LJ, Truscheid E (eds) (1974) Proteinase inhibitors, section I, plasma proteinase inhibitors. Springer Verlag, Berlin, p 14–116Google Scholar
- 21.Vogel R, Trautschold I, Werle E (1968) Natural proteinase inhibitors. Academic Press, London New York, p 57–73Google Scholar