Abstract
The phase II clinical trial in cancer patients represents an initial step in the investigation of the antitumor potential of new treatments. It is usually considered as a clinical screening designed according to a delicate compromise of the need for meaningful data weighed against exposing the patient to other treatments with possibly greater effectiveness. The definition of this compromise is subject to change resulting in continuous readaptations in the design of these trials.
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Muggia, F.M., Rozencweig, M., Staquet, M.J., McGuire, W.P. (1980). Methodology of Phase II Clinical Trial in Cancer. In: Carter, S.K., Sakurai, Y. (eds) New Anticancer Drugs. Recent Results in Cancer Research, vol 70. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81392-4_5
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DOI: https://doi.org/10.1007/978-3-642-81392-4_5
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