Skip to main content

Some New Chemotherapeutic Agents and Combinations Possibly Available for New Adjuvant Therapies of Minimal Disease

  • Chapter
Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 68))

Abstract

There are several new chemotherapeutic agents that, as their combinations, are particularly active in advanced disease and should be considered in trials of adjuvant therapies of minimal residual disease (MRD).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Reference

  1. Anderson, T., McMenamin, M. G., Schein, P. S.: Chlorozotocin, [2-(3-2-)3-(2-chloroethyl)-3-nitrosoureido γ-D-glycopyranose], an antitumor agent with modified bone marrow toxicity. Cancer Res. 35, 761–765 (1975).

    PubMed  CAS  Google Scholar 

  2. Dantchev, D., Paintrand, M., Hayat, M., Umezawa, H., Muggia, G., Mathé, G.: Electron microscopy on Golden hamster of compared cardiotoxicity of several anthracyclines. (In preparation) (1978).

    Google Scholar 

  3. Djerassi, I.: High-dose methotrexate (NSC-740) and citrovorum factor (NSC-3590) rescue: background and rationale, Part 3. Cancer Chemother. Rep. 6 3-6 (1975).

    Google Scholar 

  4. EORTC Clinical Screening Group: A phase II clinical trial of peptichemio. Biomedicine 27, 290–294 (1977).

    Google Scholar 

  5. EORTC Clinical Screening Group: A phase II clinical trial of cytembena. Biomedicine 26, 392–395 (1977).

    Google Scholar 

  6. Florentin, I., Mathé, G.: Comparative experimental immunopharmacology of three nitrosoureas: RFCNU, RPCNU and chlorozotocin. (In preparation) (1978).

    Google Scholar 

  7. Gralla, R. J., Young, C. W.: A phase II trial on vindesine in nonsmall cell carcinoma of the lung. International Workshop on Vindesine. Frankfurt, 7. July 1978.

    Google Scholar 

  8. Hayat, M., Mathé, G.: Comparative experimental oncostatic pharmacoly of three nitrosoureas: RFCNU, RPCNU and chlorozotocin. (In preparation) (1978).

    Google Scholar 

  9. Hayat, M., Brule, G., Clavel, B., Chauvergne, J., Cappelaere, P., Cattan, A., Guerrin, J., Pommatau, E., Bayssas, M., Gouveia, J., Mathé, G.: Essai thérapeutique clinique phase II du cisplatinum. Nouv. Presse Méd. (1978) (in press).

    Google Scholar 

  10. Imbach, J. L., Montero, J. L., Moruzzi, A., Serrou, B., Chenu, E., Hayat, M., Mathé, G.: The oncostatic and immunosuppressive action of new nitrosourea derivatives containing sugar radicals. Biomedicine 23, 410–413 (1975).

    PubMed  CAS  Google Scholar 

  11. Jasmin, C., Mathé, G.: Comparative experimental hematopharmacology of three nitrosoureas: RFCNU, RPCNU and chlorozotocin. (In preparation) (1978).

    Google Scholar 

  12. Mathé, G., Serrou, B., Hayat, M., De Vassal, F., Misset, J. L., Schwarzenberg, L., Machover, D., Ribaud, P., Belpomme, D., Jasmin, C., Musset, M., Montero, J. L., Imbach, J. L.: Preliminary results of phase I and II clinical trials of RFCNU, a new nitrosourea sugar derivative in digestive tract tumours. Biomedicine 27, 294–297 (1977).

    PubMed  Google Scholar 

  13. Mathé, G., Bayssas, M., De Vassal, F., Gouveia, J.: Phase II trials of three oncostatic nitrosoureas: RFCNU, RPCNU and chlorozotocin. (In preparation) (1978).

    Google Scholar 

  14. Mathé, G., Misset, J. L., De Vassal, F., Hayat, M., Gouveia, J., Machover, D., Belpomme, D., Schwarzenberg, L., Ribaud, P., Pico, J. L., Musset, M., Jasmin, C., De Luca, L.: Traitement de leucémies et hématosarcomes par la vindésine. Résultats d’un essai phase II en termes d’induction de rémission. Nouv. Presse Méd. 7, 525–528 (1978).

    Google Scholar 

  15. Mathé, G., Misset, J. L., De Vassal, F., Gouveia, J., Hayat, M., Machover, D., Belpomme, D., Pico, J. L., Schwarzenberg, L., Ribaud, P., Musset, M., Jasmin, C., De Luca, L.: Phase II clinical trial with vindesine for remission induction in acute leukemia, blastic crisis of chronic myeloid leukemia, lymphosarcoma and Hodgkin’s disease: absence of cross-resistance with vincristine. Cancer Treat. Rep. 62, 805–809 (1978).

    PubMed  Google Scholar 

  16. Mathé, G., Misset, J. L., Bayssas, M., Gouveia, J., De Vassal, F., Hayat, M., Delgado, M., Gil, M. A., Machover, D.: Does adriamycin increases survival in metastatic breast patients? Preliminary evaluation. Cancer Chemother. Pharmacol. (1978) (in press).

    Google Scholar 

  17. Mathé, G., Bayssas, M., Gouveia, J., De Vassal, F., Dantchev, D.: A propos de la Revue Générale de Jacquillat et al.: l’aclacynomyciine, une nouvelle anthracycline non alopéciante et moins cardiotoxique que l’adriamycine. Nouv. Presse Méd. (1978) (in press).

    Google Scholar 

  18. Misset, J. L., De Vassal, F., Hayat, M., Machover, D., Belpomme, D., Schwarzenberg, L., Ribaud, P., Musset, M., Jasmin, C., Mathé, G.: Phase II clinical trial with vindesine for remission induction in acute leukaemia, blastic crisis of chronic myeloid leukaemia, lymphosarcoma and Hodgkin’s disease. Absence of cross resistance with vincristine. Med. Oncol. 3, S21 (1977).

    Google Scholar 

  19. Powles, T., Smith, I. E.: Vindesine in the treatment of breast cancer. International Workshop on Vindesine. Frankfurt, 7. July 1978.

    Google Scholar 

  20. Retsas, S., Newton, K. A., Westbury, G.: Vindesine in treatment of advanced malignant melanoma. International Workshop on Vindesine. Frankfurt, 7. July 1978.

    Google Scholar 

  21. Schwarzenberg, L., Mathé, G., Hayat, M., De Vassal, F., Amiel, J. L., Cattan, A., Schneider, M., Schlumberger, J. R., Jasmin, C., Ngo Minh Man: Une nouvelle combinaison de méthotrexate-acide folinique pour le traitement des cancers (leucémies et tumeurs solides). Presse Méd. 77, 385 (1969).

    PubMed  CAS  Google Scholar 

  22. Serrou, B., Imbach, J. L., Hayat, M., Mathé, G., Macieira-Coelho, A. M.: Experimental screening and pharmacology of new sugar derivatives of nitrosourea. Proc. Am. Assoc. Cancer Res. 18, 223 (Abs. 892) (1977).

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Mathé, G. et al. (1979). Some New Chemotherapeutic Agents and Combinations Possibly Available for New Adjuvant Therapies of Minimal Disease. In: Bonadonna, G., Mathé, G., Salmon, S.E. (eds) Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II. Recent Results in Cancer Research, vol 68. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81332-0_65

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-81332-0_65

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81334-4

  • Online ISBN: 978-3-642-81332-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics