Adjuvant Therapy of Operable Primary Osteosarcoma-Cancer and Leukemia Group B Experience

  • E. P. Cortes
  • J. F. Holland
  • O. Glidewell
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 68)


The major therapeutic approach to primary osteogenic sarcoma has, for many years, been radical surgery. Despite differences in pretherapeutic work-up, surgical techniques, and demography, the overall survival rates in the review of Friedman and Carter was 19.7% (253 of 1286 patients) [8]. The range was fairly small, 16%–23% in the series published. Radiologic evidence of pulmonary metastases occurs at a median of 8.5 months after potentially curative amputation [10]. The patient usually dies within 6 months from the onset of detectable pulmonary metastases [13].


Pulmonary Metastasis Protocol Deviation Leukemia Group Protocol Adherence Primary Osteogenic Sarcoma 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1979

Authors and Affiliations

  • E. P. Cortes
  • J. F. Holland
  • O. Glidewell

There are no affiliations available

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