Abstract
Newer regimens including cis-diamminedichloroplatinum (DDP) have shown a striking therapeutic efficacy against advanced testicular cancer [22]. The impact of such chemotherapy on our overall approach to this disease will be described. Preceding the description of current trials, a review of staging concepts and the prognostic implications of histology and stage is essential to understanding the concepts underlying current strategies.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Reference
American Joint Committee for Cancer Staging and End Results Reporting. 1977.
Anderson, T., Waiden, T., Javadpour, N., Anderson, T., Glatstein, E.: Recent advances in diagnosis and therapy of testicular germ cell neoplasms. Ann. Intern. Med. (in press) (1978).
Boden, G. L., Gibb, R.: Radiotherapy and testicular neoplasms. Lancet 1951 II, 1195.
Carter, S. K., Wasserman, T. H.: The chemotherapy of urologic cancer. Cancer 36, 729–749 (1975).
Chary, K., Higby, D., Henderson, E., Swinerton, K.: Phase I study of high dose cis-diamminedichloroplatinum(II) with forced diuresis. Cancer Treat. Rep. 61, 367–370 (1977).
Cheng, E., Cvitkovic, E., Wittes, R., Golbey, R.: Germ cel tumors (II): VAB II in metastatic testicular cancer. Cancer (in press) (1978).
Collins, D. H., Pugh, R. C. B.: Classification and frequency of testicular tumors. Br. J. Urol. 36, [Suppl 1], 1, (1964).
Corder, M. P., Maguire, L. C., Witte, D. L., Panther, S. K., Lovett, J. M., Dietz, B. J.: Weekly outpatient cis-platinum(II) diamminedichloride (CPDD) and diuresis with dose-limiting myelosuppression. Proc. Am. Assoc. Cancer Res./Proc. Am. Soc. Clin. Oncol. 18, 344 (1977).
Cvitkovic, E., Hayes, D., Golbey, R.: Primary combination chemotherapy (VAB III) for metastatic or unresectable germ cell tumors. Proc. Am. Assoc. Cancer Res. 17, 296 (1976) (Abs.).
Dixon, F., Moore, R.: Tumors of the male sex organs. In: Atlas of tumor pathology. Section 8, Part 31b and 32, pp. 48-127. Washington D. C.: Armed Forces Institute of Pathology.
Einhorn, L. H., Donohue, J. P.: Cis-diammine-dichloroplatinum, vinblastine, and bleomycin combination chemotherapy in dissemminated testicular cancer. Ann. Intern. Med. 87, 293–298 (1977).
Hayes, D. M., Cvitkovic, E., Golbey, R. B., Scheiner, E., Helson, L., Krakoff, I. H.: High dose cis-platinum diammine dichloride. Amelioration of renal toxicity by mannitol diuresis. Cancer 39, 1372–1381 (1977).
Higby, D. J., Wallace, H. J., Albert, D., Holland, J. F.: Diamminodichloroplatinum in the chemotherapy of testicular tumors. J. Urol. 112, 100–104 (1974).
Hussey, D. H., Luk, K. H., Johnson, D. E.: The role of radiation therapy in the treatment of germinal cell tumors of the testis other than pure seminoma. Radiology 123, 175–180 (1977).
Javadpour, N., Bergman, S.: Recent advances in testicular cancer. Curr. Probl. Surg. 25, 1–64 (1978).
Lynch, D. F., McCord, L., Nicholson, T., Richie, J., Sargents, C.: Sandwich therapy in testis tumor: current experience. J. Urol. 119, 612–613 (1977).
Maier, J. G., VanBuskirk, K. E.: Treatment of testicular germ cell malignancies. JAMA 213, 97–98 (1970).
Maier, J. G., Mittemeyer, B. T.: Carcinoma of the testis. Cancer 39, 981–986 (1977).
Merrin, C.: A new method to prevent toxicity with high doses of cisdiammine platinum (therapeutic efficacy in previously treated widespread and recurrent testicular tumors). Proc. Am. Assoc. Cancer Res./Proc. Am. Soc. Clin. Oncol. 17, 243 (1976).
Merrin, C.: Multimodal treatment of advanced testicular tumor with cis-diammine dichloroplatinum (CPDD), bleomycin (BLEO), vinblastine (VLB), vincristine (VCR) and actinomycin D. Proc. Am. Assoc. Cancer Res. 18, 298 (1977).
Mostofi, F.: Testicular tumors: epidemiologic, etiologic, and pathologic features. Cancer 32, 1186–1201 (1973).
Muggia, F. M., Jacobs, E. M.: Chemotherapy of testicular cancer: Impact on curability. Princess Takamatsu Symposium (in press) (1978).
Nitschke, R., Starling, K., Land, V., Komp, D.: Cis-platinum (PDD) in childhood malignancies. Proc. Am. Assoc. Cancer Res. 17, 310 (1976).
Osieka, R., Bruntsch, U., Gallmeier, W., Seeber, S., Schmidt, C.: Cis-diamminodichloro-platin in der Behandlung therapieresistenter maligner Hodenteratome. Dtsch. Med. Wochenschr. 101, 191–195 (1976).
Rossof, A. H., Talley, R. W., Stephens, R. L.: Phase II evaluation of single high-dose cis-diamminedichloroplatinum in gynecologic and genitourinary neoplasia. Proc. Am. Assoc. Cancer Res. 18, 97 (1977).
Samuels, M., Lancotti, V., Holoye, P., Howe, G.: Stage III testicular cancer: Complete response by substage to velban plus continuous bleomycin infusion (VB-3). Proc. Am. Assoc. Cancer Res. 18, 146 (1977).
Staubitz, W. J., Early, R., Magoss, I., Murphy, G.: Surgical management of testis tumor. J. Urol. 111, 205 (1974).
Tyrell, C., Peckham, M.: The response of lymph node metastases of testicular teratom to radiation therapy. Br. J. Urol. 48, 363–370 (1976).
Union Internationale Contre le Cancer: TNM classification of malignant tumors, 2nd ed. Geneva, 1974.
Vugrin, D., Cvitkovic, E., Whitmore, W., Golbey, R.: Prophylactic chemotherapy of testicular germ cell carcinomas (non-seminomas) Stage II following orchiectomy and retroperitoneal dissection. Proc. Am. Assoc. Cancer Res. 19, 352 (1978).
Wittes, R. E., Yagoda, A., Silvay, O., Magill, G., Whitmore, W., Krakoff, I., Golbey, R.: Chemotherapy of germ cell tumors of the testis. I. Induction of remissions with vinblastine, actinomycin D, and bleomycin. Cancer 37, 637–645 (1976).
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Muggia, F.M., Jacobs, E.M. (1979). Adjuvant Chemotherapy of Testicular Carcinoma: Need for Evaluation of Curative Strategies. In: Bonadonna, G., Mathé, G., Salmon, S.E. (eds) Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II. Recent Results in Cancer Research, vol 68. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81332-0_29
Download citation
DOI: https://doi.org/10.1007/978-3-642-81332-0_29
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81334-4
Online ISBN: 978-3-642-81332-0
eBook Packages: Springer Book Archive