Radiation Carcinogenesis

  • G. W. Dolphin
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 73)


There are two important reasons for studying the risk of induction of thyroid cancer following irradiation. One is for radiological protection purposes, to help in setting radiation exposure limits for the thyroid in children and adults; the other reason is to assess the risk of thyroid cancer following radiation treatment of the head and neck region, which may include the thyroid in the primary or scattered beam, or the use of radioiodines in therapeutic or diagnostic procedures. The purpose of this paper is to review some of the existing data on radiation-induced thyroid cancers and to evaluate the risk.


Thyroid Cancer Relative Biological Effectiveness Radiological Protection Tinea Capitis Endemic Goitre 
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  1. 1.
    Campbell H, Doll WRS, Letchner J (1963) The incidence of thyroid cancer in England and Wales. Thyroid cancer. Br Med J 2: 1370–1373Google Scholar
  2. 2.
    Case RAM, Coghill C, Davies JM, Harley JL, Hytten CA, Pearson JH, Willard SR, Alderson MR (1976) Serial mortality tables. 1. Anaplastic diseases. Institute for Cancer Research, LondonGoogle Scholar
  3. 3.
    Conard RA (1977) Summary of thyroid findings in Marshallese 22 years after exposure to radioactive fallout. In: DeGroot Li (ed) Radiation associated thyroid carcinoma. Grune Stratton, New York, p 241Google Scholar
  4. 4.
    DeSmet MP (1960) Pathological anatomy of endemic goitre. In: Endemic Goitre. WHO, Geneva, p 315Google Scholar
  5. 5.
    Dobyns BM (1977) Radiation hazard — experience with therapeutic and diagnostic iodine-131. In: DeGroot LJ (ed) Radiation associated thyroid carcinoma. Grune Stratton, New York, p457Google Scholar
  6. 6.
    Dolphin GW (1968) The risk of thyroid cancers following irradiation. Health Phys 15: 219PubMedCrossRefGoogle Scholar
  7. 7.
    Halnan KE (1966) Influence of age and sex on incidence and prognosis of thyroid cancer. Cancer 19: 11, 1534PubMedCrossRefGoogle Scholar
  8. 8.
    Hempelmann LH, Hall WJ, Phillips M, Cooper RA, Ames WR (1975) Neoplasms in persons treated with X-rays in infancy: fourth survey in 20 years. J Natl Cancer Inst 55: 519PubMedGoogle Scholar
  9. 9.
    McDougal IR (1974) Thyroid cancer after iodine-131 therapy. JAMA 227: 438Google Scholar
  10. 10.
    Modan B, Ron E, Werner A (1977) Thyroid cancer following scalp irradiation. Radiology 123: 741PubMedGoogle Scholar
  11. 11.
    Parker LN, Belsky JL, Yamamoto T, Kawamoto S, Keehn RJ (1974) Thyroid carcinoma diagnosed between 13 and 26 years after exposure to atomic radiation. Atomic bomb casualty commission, Hiroshima, Jpn. Technical Report No 5–73Google Scholar
  12. 12.
    Roudebush CP, DeGroot LJ (1977) The natural history of radiation associated thyroid cancer. In: DeGroot LJ (ed) Radiation associated thyroid carcinoma. Grune & Stratton, New York, p 97Google Scholar
  13. 13.
    Waterhouse J, Muir C, Correa P, Powell J (1976) Cancer incidence in five continents. Publ international agency for research on cancer, LyonGoogle Scholar
  14. 14.
    Werner A, Modan B, Davidoff D (1968) Doses to brain, skull and thyroid following X-ray therapy for tinea captiis. Phys Med Biol 13: 247PubMedCrossRefGoogle Scholar
  15. 15.
    Winship T, Rosvol R (1961) Childhood thyroid carcinoma. Cancer 14: 734PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • G. W. Dolphin
    • 1
  1. 1.National Radiological Protection BoardHarwell, DidcotGB

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